PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4810
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Item Evaluation of choroidal thickness in children with acute asthma attack by optical coherence tomography(2021) Kurultay, Isil; Sancakli, Ozlem; 34482738Objective: To evaluate the change in central choroidal thickness in children with asthma attack before and after treatment with beta(2) agonists. Materials and methods: About 100 eyes of 50 patients (5-17 years old) with visual acuity of 20/20 who had no retinal, choroidal, and systemic comorbidity were examined by enhanced depth optical coherence tomography (EDI-OCT) before and after asthma attack treatment. Sixty eyes of 30 healthy children of similar age and gender were evaluated as the control group. The central choroidal thickness, peak expiratory flow (PEF), forced expiratory volume 1(FEV1), oxygen saturation, and heart rate were evaluated. Results: The mean age of the patients was 9.2 +/- 3.1 years, and the mean saturation values of patients was 97.2 +/- 1.3 before treatment, and it increased to 98.3 +/- 0.9 after treatment with a statistically significant difference. The mean FEV1 values were 80.8 +/- 15.2 before, and 92.7 +/- 12.9 after the treatment and PEF values were 75.9 +/- 18.6 before and 89.3 +/- 18.9 after treatment. This differences were statistically significant (p < 0.001). The average choroidal thickness before the treatment were 310.4 +/- 34.2 mu m and decreased to 302.7 +/- 34.4 mu m after the treatment, this decrease was statistically significant (p < 0.001). The mean choroidal thickness of the control group was 303.0 +/- 7.3 mu m and compared to the pre-treatment and post-treatment values, it was more similar to the post-treatment values, although there was no statistically difference. Conclusion: In our study, it was shown that choroidal thickness was significantly reduced in children with asthma who received attack treatment with beta(2) agonists, and it was similar to the control group after the treatment.Item Spectral domain optical coherence tomography findings of patients with ankylosing spondylitis(2020) Kal, Ali; Ulusoy, Mahmut Oguz; Orturk, Caner; 0000-0001-7544-5790; 32533454; AAJ-4936-2021Purpose The aim of this study is to evaluate the possible effects of (ankylosing spondylitis) AS on choroidal thickness (CT) and other retinal layers using spectral domain optical coherence tomography (SD-OCT). Methods This cross-sectional study group comprised 41 AS patients and age and sex-matched 46 control subjects. None of our patients had active anterior uveitis during the measurements. We evaluated and compared CT, retinal nerve fiber layer (RNFL) thickness, ganglion cell complex (GCC) thickness, focal loss volume (FLV) and global loss volume (GLV) of the participants. Results The CT of the patients at 1500 mu m (286.20 mu m +/- 65.81), 1000 mu m (309.55 mu m +/- 85.33) nasally to the fovea and subfoveal layer (339.93 mu m +/- 69.93) were thicker than in controls (p = 0.007,p = 0.037,p = 0.008). Except nasal layer, all RNFL layers were significantly thinner than controls (p < 0.001). GCC and macular thickness were also thinner than controls (p < 0.001). Conclusion In conclusion, present findings may suggest that the AS disease may affect the choroidal, RNFL and GCC thickness by disease's own inflammatory effect, independently from the uveitis history.Item Structural Analysis of the Retina and Choroid before and after Carotid Artery Surgery(2019) Bayar, Sezin Akca; Ozturker, Zeynep Kayaarasi; Pinarci, Eylem Yaman; Ercan, Zeynep Eylul; Akay, Hakki Tankut; Yilmaz, Gursel; 0000-0002-9915-3781; 31507205; AAQ-3136-2020Purpose: To evaluate retinal and choroidal changes in patients with internal carotid artery stenosis who had undergone carotid artery stenting or endarterectomy. Methods: The study included 43 patients with internal carotid artery (ICA) stenosis that required stenting or endarterectomy and 40 healthy controls. Patients were divided into two groups according to the degree of stenosis evaluated by magnetic resonance angiography. Group 1 consisted of patients having ICA stenosis of 50 to 70%, and Group 2 has more than 70%. Enhanced depth imaging optical coherence tomography (EDI-OCT) was used to measure the retinal thickness (RT) and choroidal thickness (CT) in all subjects before surgery and at 1, 3, and 6 months after surgery. Results: Subfoveal and parafoveal CT were significantly lower in patients with ICA stenosis than the control group (p < .05, respectively). Patients with 50-70% stenosis had a significant increase in the CT at 1, 3, and 6 months after ICA stenting or endarterectomy (p < .05). Patients with >%70 stenosis did not have a significant increase in the CT at any time after ICA stenting or endarterectomy. Retinal thickness was not statistically different between the patients with ICA stenosis and the control subjects, and RT showed no significant change in patients with ICA stenosis before and after the surgery. Conclusion: Choroidal thickness was significantly thinner in patients with internal carotid artery stenosis. ICA stenting provided a recovery in the choroidal thickness in patients with moderate to advanced stenosis.