Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/11727/4809

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Author: search.filters.author.Kuru, IlhamiHas files: No

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    Prediction of disability in trigger finger: a cross-sectional and longitudinal study
    (2023) Namaldi, Seda; Kuru, Cigdem Ayhan; Kuru, Ilhami; 36324191
    The aim of this prospective study of 55 patients was to analyse the cross-sectional and longitudinal relationship between disability and physical and psychological variables after conservative treatment of trigger finger and to determine the predictive factors for the post-treatment disability score and change in disability score. The primary outcome measure was the Disabilities of the Arm, Shoulder, and Hand questionnaire. Potential predictive factors included pain, number of triggering events, depression, anxiety and kinesiophobia. Disability correlated strongly with anxiety, moderately with pain and depression and weakly with triggering and kinesiophobia. The change in depression score correlated significantly with the change in disability score. Post-treatment pain and anxiety scores accounted for 47% of the explained variance in disability score. Improvement in depression after treatment accounted for 18% of the explained variance in disability change score. Psychological variables appear to be potential predictors of disability.
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    The effectiveness of intra-articular bleomycin versus methotrexate in a chronic synovitis model
    (2020) Maralcan, Gokhan; Inan, Ulukan; Kuru, Ilhami; Aktepe, Fatma; Isik, Cengiz; 0000-0002-1268-1451; AAJ-4341-2021
    Objective: To compare the effectiveness of methotrexate which was proven to be effective for rheumatoid arthritis and bleomycin in a synovitis model. Our aim was to show whether bleomycin could be used for chemical synovectomy purposes. Design: Experimental study Setting: Department of Orthopedics and Traumatology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey Subjects: Fifteen mature New Zealand rabbits were studied. Synovitis was induced by repeated injections of lambda carrageenan. Interventions: Knees of the subjects were grouped as sham, bleomycin and methotrexate. After synovitis occurred, sterile saline injected knees formed the sham group, bleomycin and methotrexate injected knees composed the study groups. In the 9th week of the study, animals were euthanised. Standard specimens were harvested from all knees. Immunoperoxidase staining was performed. Main outcome measures: The intensity of synovitis was evaluated with thickness of the synovial cell layers, intensity of inflammatory infiltrate and iNOS expression in cells. Results: Thickness of the synovial cell layers was greater in the sham group than in the study groups (p<0.05). Intensity of inflammatory infiltrate, lymphoplasmacytoid infiltrate, and histiocytes in the sham group were greater than in the study groups (p<0.05). iNOS expression in histocytes and plasma cells was significantly decreased in the study groups compared to sham operated group (p<0.05). There was no statistically significant difference between bleomycin and methotrexate groups with respect to synovial cell layer thickness and lymphoplasmacytoid infiltrate. Conclusions: According to these results, intraarticular bleomycin seems as effective as methotrexate in experimental synovitis model.