Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/11727/4809

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    Evaluation of Iridocorneal Angle, Choroidal Thickness, and Retinal Nerve Fiber Layer Thickness in Children With a History of Retinopathy of Prematurity
    (2020) Ulusoy, Mahmut Oguz; Kivanc, Sertac Argun; Kal, Ali; 31790064
    Purpose: Retinopathy of prematurity (ROP) is proliferative retinopathy affecting premature infants associated with abnormal maturation of the retinal vasculature. We sought to evaluate iridocorneal angle, choroidal thickness, and retinal nerve fiber layer thickness (RNFLT) of the children that have a history of ROP using spectral-domain optical coherence tomography. Patients and Methods: Fifty eyes of 28 children with a history of ROP and 46 eyes of 23 healthy school-aged children were included in this study. RNFLT, choroidal thickness, and iridocorneal angle parameters [trabecular iris angle, angle opening distance (AOD500), and trabecular iris space area (TISA500) 500 mu m from the scleral spur] were evaluated using spectral-domain optical coherence tomography. Student t test was used to compare the mean of the parameters. Correlations between the variables were investigated based on the Pearson or Spearman correlation coefficient. Results: Subfoveal (ROP: 253.98 +/- 42.5; control: 286.2 +/- 71.9; P=0.045), 500 mu m (ROP: 242.04 +/- 41.8; control: 276.7 +/- 45.3; P=0.003), 1000 mu m (ROP: 237 +/- 39.7; control: 270.15 +/- 55.93; P=0.007), and 1500 mu m (ROP: 224.16 +/- 37.5; control: 259.75 +/- 55.2; P=0.003) temporal choroidal thicknesses were significantly thinner in ROP history children. None of the RNFLT parameters and ganglion cell complex thickness were different between groups. Iridocorneal angle parameters were significantly lower in children with ROP history. (trabecular iris angle: ROP=31.35 +/- 3.9 degrees, control=35.4 +/- 4.5 degrees, P<0.001; TISA500: ROP=0.167 +/- 0.05 mm(2), control=0.21 +/- 0.05 mm(2), P=0.003; AOD500: ROP=480.96 +/- 160.4 mu m, control=542.95 +/- 161.2 mu m, P=0.035). Conclusions: ROP is associated with differences in the iridocorneal angle. Possible iridocorneal angle pathology should be a consideration in children with a history of ROP.
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    Spectral domain optical coherence tomography findings of patients with ankylosing spondylitis
    (2020) Kal, Ali; Ulusoy, Mahmut Oguz; Orturk, Caner; 0000-0001-7544-5790; 32533454; AAJ-4936-2021
    Purpose The aim of this study is to evaluate the possible effects of (ankylosing spondylitis) AS on choroidal thickness (CT) and other retinal layers using spectral domain optical coherence tomography (SD-OCT). Methods This cross-sectional study group comprised 41 AS patients and age and sex-matched 46 control subjects. None of our patients had active anterior uveitis during the measurements. We evaluated and compared CT, retinal nerve fiber layer (RNFL) thickness, ganglion cell complex (GCC) thickness, focal loss volume (FLV) and global loss volume (GLV) of the participants. Results The CT of the patients at 1500 mu m (286.20 mu m +/- 65.81), 1000 mu m (309.55 mu m +/- 85.33) nasally to the fovea and subfoveal layer (339.93 mu m +/- 69.93) were thicker than in controls (p = 0.007,p = 0.037,p = 0.008). Except nasal layer, all RNFL layers were significantly thinner than controls (p < 0.001). GCC and macular thickness were also thinner than controls (p < 0.001). Conclusion In conclusion, present findings may suggest that the AS disease may affect the choroidal, RNFL and GCC thickness by disease's own inflammatory effect, independently from the uveitis history.
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    Retinal vascular density evaluation of migraine patients with and without aura and association with white matter hyperintensities
    (2019) Ulusoy, Mahmut Oguz; Horosanli, Bahriye; Kal, Ali; 30762208
    Underlying pathophysiological mechanism of migraine is not all clear; however, recent reports suggested that neurovascular system is involved. We aimed to evaluate the retinal vessel densities of migraine patients with and without aura and the associations with white matter hyperintensities (WMH), using optical coherence tomography angiography (OCTA). We recruited 28 migraine with aura (MWA) patients, 26 migraine without aura (MWO) and age and sex-matched 34 healthy controls in our study. All participants were evaluated with optical coherence tomography (OCT) and OCTA for optic nerve parameters and retinal vessel densities with RTVue XR AVANTI. On macular OCTA, superficial and deeper retinal foveal vessel density (VD) were significantly lesser in MWA and MWO than controls. On optic nerve OCTA, whole optic disc, peripapillary, superior hemisphere, superior layer and temporal layer VD were significantly lesser in MWA and MWO. In group of MWA with the WMH, deeper foveal VD and superior hemisphere VD, average RNFL, superior hemisphere and superior layer were significantly lesser and also foveal avascular zone was significantly larger than the group of without WMH. Alterations of VD in patients with migraine are showed in our study. In addition, in group of MWA these alterations have associations with WMH. Supporting these findings with further reports can be useful to understand the pathophysiology of this disease.