Wos Açık Erişimli Yayınlar
Permanent URI for this collectionhttps://hdl.handle.net/11727/10754
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Item Antioxidant treatment of increased sperm DNA fragmentation: Complex combinations are not more successful(2020) Ozer, Cevahir; 0000-0002-7850-6912; 33348968; AAM-2222-2020Objective: Oral antioxidant supplementation is part of the treatment of infertility associated with oxidative stress-related sperm damage. It is possible to assume that the combined use of antioxidants will be better than single agent use. The purpose of this study was to compare the effectiveness of different antioxidant combinations in infertile men with increased sperm DNA fragmentation. Materials and methods: We retrospectively reviewed the records of 637 patients who underwent antioxidant support therapy for increased sperm DNA damage between 2014 and 2019. Patients with DNA damage of 30% or more were included study. Result: A total of 163 patients with follow-up data and who fulfilled the study criteria were included in the study. There were four different treatment groups. No statistically significant differences were found between the groups. After 3 months of antioxidant treatment, there was a statistically significant decrease in sperm DNA damage in all treatment groups. However, there was no statistically significant difference between the treatment groups. Conclusions: The complexity of the antioxidant combination may not contribute to the success of the treatment or may cause possible side effects, increase the cost of treatment and decrease patient compliance.Item Clinical results of shock wave lithotripsy treatment in elderly patients with kidney stones: Results of 1433 patients(2020) Ozer, Cevahir; Tekin, Mehmet Ilteris; 0000-0002-7850-6912; 33348965; AAM-2222-2020Objective: In this study, it was aimed to evaluate the efficacy and safety of SWL treatment in elderly patients with kidney stones. Materials and methods: Data from a total of 3024 patients who underwent SWL treatment for urinary tract stone disease in three centers of our university were evaluated retrospectively. A total of 1433 patients in the adult age group treated for single kidney stones were included in the study. The patients were divided into 3 groups (18-40, 41-64 and >= 65) years depending on their age. Demographic data, stone parameters, stone-free rate (SFR) and clinically insignificant residual fragment (CIRF) rate, number of SWL sessions and complication rate were analyzed according to the age groups. Results: The mean age of the patients was 47.38 +/- 13.24 years. Stone size was significantly lower in the 18-40 years age group compared to other groups (p = 0.000) and the stones were mostly located on the right side in this age group (p = 0.007). There was no significant relationship between age groups and gender, stone localization, and number of SWL sessions. The overall SFR was 66.4%. Although the SFR was lower (61.4%) and the rate of multiple sessions (27.2%) was higher in >= 65 years group, there was no statistically significant difference between age groups regarding SFR, CIRF, need for additional sessions, and complication rates. Conclusions: Due to its similar clinical results, treatment of SWL should not be ignored as a treatment option in the geriatric patient group with kidney stones.Item Transurethral Resection of Ejaculatory Duct in Primary Infertile Men with Distal Ejaculatory Duct Obstruction(2019) Ozer, Cevahir; Goren, Mehmet Resit; 0000-0001-6037-7991; 0000-0002-7850-6912; 0000-0002-2001-1386; AAM-2222-2020; Y-6143-2019Objective: We evaluated the outcome of transurethral resection for the treatment of distal ejaculatory duct obstruction with primary infertile men. Materials and Methods: We retrospectively evaluated 23 primary infertile men, who had distal ejaculatory duct obstruction, between June 2006 and July 2018. All patients were treated by transurethral resection of the ejaculatory duct. Results: The mean age of the patients was 31.82 +/- 5.01 years. Preoperative and postoperative seminal parameters were compared. There was a statistically significant increase in ejaculate volume, sperm concentration, sperm motility and total motile sperm count. Conclusion: Transurethral resection of the ejaculatory duct improved sperm parameters in most of the primary infertile men with distal ejaculatory duct obstruction. Transurethral resection may also decrease the need for assisted reproduction methods and allow in-vitro fertilization/intracytoplasmic sperm injection with ejaculated sperm in some azoospermic patients.Item Varicocelectomy in Patients with Non-obstructive Azoospermia(2019) Ozer, Cevahir; Goren, Mehmet Rasit; Gul, Umit; Tunc, Tahsin; Guvel, Sezgin; 0000-0001-6037-7991; AAM-2222-2020Objective: We evaluated the outcomes of varicocelectomy in men with non-obstructive azoospermia (NOA) and a palpable varicocele. Materials and Methods: We retrospectively evaluated 25 male patients with NOA having a palpable varicocele, between May 2006 and December 2018. Age, duration of infertility, testicular volume, grade and side of varicocele, varicocelectomy technique, and serum follicle-stimulating hormone, serum luteinizing hormone and serum testosterone levels were analyzed. Results: The mean age of the patients was 30.68 +/- 3.91 years. Of the 25 patients, 5 (20%) had motile sperm in the ejaculate in the postoperative semen analysis. There were no predictive factors affecting the appearance of the sperm in the ejaculate. Conclusion: Varicocelectomy should be considered a treatment option for men with NOA having a palpable varicocele.Item Papillary renal cell carcinoma within a renal oncocytoma: Case report of very rare coexistence(2014) Ozer, Cevahir; Goren, Mehmet Resit; Egilmez, Tulga; Bal, Nebil; 25553171Renal oncocytomas accounts for 3% to 9% of primary renal neoplasms. The coexistence of renal cell carcinoma (RCC) within the oncocytoma is extremely rare. We report the case of an asyptomatic 74-year-old man with papillary RCC within oncocytoma managed with left radical nephrectomy.Item Author response: Papillary RCC and oncocytoma: Longer follow-up reported(2015) Ozer, Cevahir; Goren, Mehmet Resit; Egilmez, Tulga; Bal, Nebil; 26085864Item Bilateral renal leiomyoma with 5 year follow-up: Case report(2015) Goren, Mehmet Resit; Erbay, Gurcan; Ozer, Cevahir; Goren, Vinil; Bal, Nebil; 26664510Renal leiomyomas are exceptionally rare benign tumours of the kidney. Although the renal leiomyomas usually do not metastasize, the differential diagnosis between renal leiomyomas and malign lesions (leiomyosarcoma or renal cell carcinoma) cannot be done by radiological examinations, but is possible by histological examination. Surgery is the preferred treatment. After surgery, the prognosis is excellent without recurrence. Although uterine leiomyomas can be multicentric, renal leiomyomas have been single lesions. We report an incidentally detected case of bilateral renal leiomyoma in a 50-year-old woman with a 5-year follow-up. We also review the literature and discuss clinical, radiological and histological features of renal leiomyomas.Item Bariatric Surgery and Urinary Stone Disease(2016) Ozer, Cevahir; Egilmez, Tulga; 0000-0002-7850-6912; 0000-0001-5644-5672; 0000-0001-6037-7991; AAM-2222-2020; AAK-9166-2021Obesity is a major public health problem and has been suggested to play a role in the etiology of urinary tract stone disease. Furthermore, the increasingly widespread use of surgery in the treatment of obesity also is related with urinary stone disease. In daily practice, patients to whom obesity surgery has been planned or who have undergone obesity surgery are seen more frequently. This review aims to highlight the urological evaluation and management of this patient group.Item Retroperitoneal Schwannoma: A Case Report(2017) Ozer, Cevahir; Goren, Mehmet Resit; Hasbay, Bermal; Erbay, Gurcan; 0000-0002-7850-6912; 0000-0002-2001-1386; 0000-0002-1706-8680; AAM-2222-2020; Y-6143-2019; AAK-5370-2021Schwannomas are benign tumors originating from Schwann cells of the neural sheaths. Only 0.3% to 3% of the schwannomas are located the retroperitoneal space. Most schwannomas are asymptomatic and often found incidentally. The ideal treatment is complete surgical excision. Here, we report a case of a 49-year-old woman with retroperitoneal schwannoma.