Wos Açık Erişimli Yayınlar
Permanent URI for this collectionhttps://hdl.handle.net/11727/10754
Browse
3 results
Search Results
Item Hypothenar hammer syndrome: a case series and literature review(2015) Sahin, Mehmet Sukru; Ozyurekoglu, Tuna; Cakmak, Gokhan; 25741914Objectives: This study aims to report our experience regarding patients who were surgically treated due to hypothenar hammer syndrome and review the related literature. Patients and methods: The study included 11 hands of eight patients (5 males, 3 females; mean age 48 years; range 29 to 60 years) who underwent surgery due to hypothenar hammer syndrome between September 2004 and March 2013. Mean follow-up period was 50 months (range 3-103 months). The time of symptom onset, occupational history, and detailed physical examination findings were recorded. Surgery was performed under sedation and axillary anesthesia. Distal segment of the forearm, all thrombosed segments of the Guyon and superficial arch were removed. Reconstruction of the ulnar artery and the superficial arch was performed using vein grafts obtained from the forearm. Results: While all patients' dominant hand was affected, both hands were affected in three patients. All patients complained of pain and color change in one finger or multiple fingers. While minimal amputation and debridement of fingertip pulp was performed in two patients, all other patients recovered uneventfully. Patency of the ulnar artery was uneventful at follow-up in five of the eight patients, whereas three patients were performed revision surgery for a new vein graft. Most patient complaints resolved during the follow-up period. Conclusion: Hypothenar hammer syndrome is a disease of the upper extremities that should be considered in patients with digital ischemia, and a history of manual labor and smoking. Although this disease can be treated with conservative therapy, advance-stage patients who fail to respond to conservative treatment can be treated surgically with vein grafts.Item Effect of pentoxifylline on healing of segmental bone defects and angiogenesis(2015) Cakmak, Gokhan; Sahin, Mehmet Sukru; Ozdemir, B. Handan; Karadeniz, Emre; 26511696Objective: The aim of this study was to determine the effect of pentoxifylline (PTX) on angiogenesis and the healing of a critical-sized segmental defect of the radius diaphysis in a rat model, using radiological and histological grading systems. Methods: The study included 24 female Sprague-Dawley rats (weight: 300 +/- 20 g) divided into 4 groups. A critical-sized segmental defect was created in the radius diaphysis in all rats. In Group 1, morcellized iliac crest autografts were used to fill the segmental bone defect. In Group 2, segmental bone defects were filled using morcellized iliac crest autografts, and 25 mg/kg/day PTX was applied intraperitoneally. In Group 3, the segmental bone defects were not filled, and in Group 4 the segmental bone defects were left unfilled, and an intraperitoneal (IP) dose of 25 mg/kg/day PTX was applied. Rats were sacrificed at postoperative Week 8, and defects were evaluated using radiographic, histological and immunohistochemical methods. Results: There were significant differences between Group 1 and 2 according to radiological evaluation (p = 0.003) and quality of union at the defect site (p = 0.01). Union quality was higher in Group 4 than Group 3 (p = 0.01). Cluster of differentiation 31 (CD31) and vascular endothelial growth factor (VEGF) levels were higher in Group 2 than in Groups 3 and 4. Conclusion: According to radiological and histological parameters, PTX appears to improve angiogenesis and healing of segmental cortical bone defects of the radius in a rat model.Item Sciatic Schwannoma-Rare Cause of Sciatica: A Case Report(2015) Cakmak, Gokhan; Ulusal, Ali E.; Bilgic, Serkan; Tuncay, Cengiz; 0000-0001-5856-8895; AAF-3988-2021Schwannoma are the most common benign tumors of the peripheral nervous system. In this article we reported a case of sciatic nerve schwannoma, cause of nondiscogenic sciatica, which was treated successfully with surgical excision.