Başkent Üniversitesi Makaleler

Permanent URI for this collectionhttps://hdl.handle.net/11727/13096

Browse

Filters

2003 - 200912020 - 20231

Settings

Subject: search.filters.subject.Egypt

Search Results

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    The Relationship Between HLA Typing and HCV Infection and Outcome of Renal Transplantation in HCV Positive Patients
    (Başkent Üniversitesi, 2003-06) Hadhoud, Alaa; Abdulaziz, Azza M.; Al Menawi, Lubna; Shaheen, F.A.; Abdulghaffar, Aliah; Abas, Fahd Al; F. Al Mobrak, Mohammed
    The role of Human Leukocytic Antigen (HLA) antigens in susceptibility to Hepatitis C Virus (HCV) infection is still being debated. We analyzed HLA phenotype frequencies in two major ethnic groups, namely Egyptian and Saudi nationals. The Egyptian group included 110 patients of whom 55 were HCV positive and the other 55 HCV negative (control group). The Saudi group included 146 HCV positive patients and 122 HCV negative individuals (control group). The results for the Egyptian population revealed increased frequencies of some HLA phenotypes and decreased frequencies of others but without any statistically significant difference. In contrast, in the Saudi population, the HLA-A19 phenotype was significantly increased in HCV positive patients when compared with the control group while significantly decreased frequencies were found for HLA-B8, HLA-DRI and HLA DR3. Our data suggest that there was no significant association between HLA phenotypes and susceptibility to HCV infection among the Egyptian population while the overall data of the Saudi population seem to indicate that the expression of particular HLA alleles could be associated with susceptibility or resistance to the HCV infection. Further studies on larger numbers of patients are needed to support the role of the HLA system in HCV infection. A total of 108 HCV positive patients underwent renal transplantation at the Jeddah Kidney Center and the results were compared with 100 age and sex-matched controls. Graft survival at 36 months was 82% and 86% for HCV positive and control subjects respectively while patient survival was respectively 90% and 91%. Our data suggest that the outcome, at least in the short-time, of renal transplantation in HCV positive patients is very good.
  • No Thumbnail Available
    Item
    Geriatric Burns in Ain Shams University Burn Unit: A Comparative Epidemiological Study
    (Başkent Üniversitesi, 2023-09) Amr Mabrouk; Mai Raafat Hammad; Adel Mabrouk; Mohamed Samir Badawy
    ABSTRACT OBJECTIVES: In Egypt, the geriatric burn population faces unique challenges, and understanding the problem is crucial for effective management. Here, we examined the epidemiology and outcomes of geriatric patients presenting to the Ain Shams University burn unit, over a period from January 2019 to July 2022. MATERIALS AND METHODS: This prospective study investigated all patients older than 60 years of age who presented to the Ain Shams University Burn Unit from January 2019 to July 2022; we compared findings with our previous work published 20 years ago, in which we examined the same population from May 1995 to October 2001. The parameters investigated were patient characteristics/demographics, seasonal and day/hour variations in burn incidence, place of residence and site where burn injury occurred, type and extent of burns, treatment and hospital stay, and morbidity/mortality rates. RESULTS: Despite the number of geriatric patients presenting to our burn unit being higher, a lower percentage required admission. Early excision and grafting were performed with a higher frequency, which may be attributed to the fewer patients with chronic illnesses. There was a reduction in both morbidity and mortality. CONCLUSIONS: Substantial changes have been made in recent years in the approach to geriatric burns, including with prevention strategies and early intervention, which have led to a reduction in both morbidity and mortality among our patients. Multidisciplinary care, involving a team of health care professionals, including burn and plastic surgeons, geriatricians, and occupational therapists, is necessary to address the complex needs of this population.