Wos İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4807
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Item Anxiety, depression, and sexual dysfunction in patients with psoriasis(2022) Dogan, Yusuf; Kilic, Fatma; Ozcelik, SinanBackground: There are few studies investigating the association between psoriasis and depression, anxiety, sexual dysfunction in the literature. Aims: We aimed to investigate depression, anxiety, and sexual dysfunction in patients with psoriasis and the association between the psychiatric comorbidity and the severity and involvement sites of psoriasis. Materials and Methods: A total of 200 participants, including 100 psoriasis patients and 100 healthy volunteers as a control group, were included in the study. All participants were questioned about sociodemographic characteristics, smoking, alcohol use, and comorbidities. All participants completed the Dermatology Life Quality Index, Beck Depression Scale, Beck Anxiety Scale, Arizona Sexual Experiences Scale, Female Sexual Function Scale/International Erectile Function Index. Results: In the psoriasis group, an increased risk for depression and anxiety was observed, regardless of the clinical features and severity of psoriasis, and a positive correlation was detected between the severity of the disease and impaired quality of life. An increased risk for sexual dysfunction regardless of clinical features and severity in male patients with psoriasis was detected compared with the control group. It was found that the risk for erectile dysfunction in patients with psoriasis increased regardless of the risk factors such as smoking, alcohol, diabetes, hypertension, and cardiovascular disease. Conclusion: Our study shows that psoriasis increases the risk for impaired quality of life, depression, anxiety, and sexual dysfunction in individuals. This increase is not always associated with the clinical characteristics of psoriasis such as severity, duration, and sites of involvement. Therefore, dermatologists should consider not only the skin findings of psoriasis but also the psychosocial status of the patient and refer the patient to psychiatry if necessary.Item The mid-term effects on quality of life and foot functions following pilon fracture(2020) Yaradilmis, Yuksel Ugur; Okkaoglu, Mustafa Caner; Kilic, Alparslan; Haberal, Bahtiyar; Demirkale, Ismail; Altay, Murat; 0000-0002-1668-6997; 32946104; W-9080-2019BACKGROUND: Although pilon fractures are uncommon, they are of importance to orthopaedic surgeons because of the difficulty of treatment. Poor outcomes and high complication rates are seen despite various surgical methods. This study aims to examine the changes affecting the quality of life and foot functions in patients applied with open reduction and internal fixation (ORIF) for a pilon fracture. METHODS: In this study, a total of 45 patients treated with ORIF for a pilon fracture in our clinic between January 2010 and December 2016 were evaluated with AOFAS and SF-12 in a total of 10 categories according to demographic data, fracture classification and surgical technique. In addition to functional values, patient records were examined regarding complications, including infection, soft-tissue defect, malalignment, non-union, arthrosis and Sudeck atrophy. In patients with AOFAS <85 and low SF-12 scores, variables were examined and the relationship with complications was evaluated. RESULTS: The mean follow-up period was 3.7 years (range 2 to 7). The AOFAS value was determined to fall to <85 when the Ruedi Allgower classification increased (p=0.010), when AO classification increased (p=0.020), when there was a concomitant lateral malleolar fracture (p=0.028), and when the status was non-anatomic according to the Ovadia Bell criteria (p=0.031). The SF-12 PCS value was observed to decrease when the Ruedi Allgower classification increased ( p=0.018) and when the status was non-anatomic according to the Ovadia Bell criteria (p=0.012). A correlation was determined between the SF-12 PCS and the AOFAS values (p=0.000). CONCLUSION: The reasons for the failure of ORIF in tibia pilon fractures were found to be Ruedi 3 classification, concomitant lateral malleolar fracture, and non-anatomic surgical reduction. Failure in foot functions has a direct effect on quality of life in both the short and mid term.Item Association Between Familial Mediterranean Fever and Cachexia in Females(2020) Durmaz, Yunus; Ilhanli, Ilker; Cengiz, Ahmet Kivanc; Kaptanoglu, Ece; Ozkan Hasbek, Zekiye; Hizmetli, Sami; 33758804Objectives: This study aims to investigate the association between familial Mediterranean fever (FMF) and cachexia in females. Patients and methods: The study included 32 female FMF patients (median age 27.50 years; range, 18 to 50 years) and 30 female healthy controls (median age 32 years; range, 18 to 50 years). Patients were classified according to Tel-Hashomer criteria. Circumference of arm, waist, and thigh was recorded. Short form 36 (SF-36) and Multidimensional Assessment of Fatigue (MAF) scale were applied. Composition of the body was measured with dual X-ray absorption. Muscle strength was measured with an isokinetic dynamometer, and strength of hand grip was measured from dominant hand with a hand dynamometer. C-reactive protein, erythrocyte sedimentation rate, fibrinogen and serum creatinine kinase (CK) levels were recorded. Results: Body mass index was significantly higher in controls. Twelve patients and one control had cachexia. CK level was significantly higher in patients than controls. Mass of muscle without fat was significantly higher in patients than controls. Peak torque values of extension and flexion at the velocity of 60 degrees/second [Newton meter (Nm)], and value of total work during extension at the velocity of 240 degrees/second (Nm) in isokinetic measures were significantly higher in controls. MAF score was significantly higher in patients with cachexia than patients without cachexia where the subscale scores of SF-36, except the vitality score, were significantly lower in patients with cachexia. However, Tel-Hashomer score was significantly higher in patients with cachexia. Conclusion: This study pointed at a significant association between cachexia and FMF in females. Muscle endurance was not affected in FMF patients with cachexia; however, decreased muscle strength, impaired quality of life and increased fatigue were observed in these patients.Item Parents' View on Quality of Life after Cochlear Implantation in Children with Auditory Neuropathy(2019) Tokat, Taskin; Catli, Tolgahan; Bozkurt, Ergun Basaran; Atsal, Gorkem; Muderris, Togay; Olgun, Levent; 31846909OBJECTIVES: The aim of this study is to evaluate the quality of life in pediatric patients with auditory neuropathy according to the perspective of their parents after cochlear implantation. MATERIALS and METHODS: The pediatric patients, who underwent cochlear implantation with the diagnosis of auditory neuropathy at Izmir Bozyaka Training and Research Hospital ENT Clinic between January 1997 and May 2017, were included to the study. "Parents' Perspective tonnaire" developed by Nottingham Pediatric Cochlear Implant Programme was used in the study. The questionnaire was composed of 11 subscales and 58 questions in total. RESULTS: The study included 26 pediatric patients (14 female, 12 male) who used cochlear implant for at least 1 year. The mean age of patients was 10.91 +/- 3.85(4.3-17.3 years old) and implantation age varied between 14 months and 80 months. (median; 35.65 +/- 20.03 months). Patients who attended school had more self-confidence, and also those having implant use over 6 years had a better self confidence and social relationship. CONCLUSION: Cochlear implantation not only improves the ability of hearing but also provides development of speech and language skills and therefore enhancing the patient's quality of life. From the perspective of parents, the use of cochlear implant in the children with auditory neuropathy improves the quality of life in many different ways. The perspective of parents can provide a multidimensional evaluation about the child's progress, therefore, it should be taken into consideration by the staff in implant centers.Item Effects of right ventricular dysfunction on exercise capacity and quality of life and associations with serum NT-proBNP levels in COPD: an observational study(2014) Ozdemirel, Tugce Sahin; Ulasli, Sevinc Sarinc; Yetis, Begum; Karacaglar, Emir; Byraktar, Nilufer; Ulubay, GayeObjective: During the course of chronic obstructive pulmonary disease (COPD), pulmonary hypertension (PH) and right ventricular (RV) failure may develop due to elevated afterload of the RV. In those patients, exercise capacity is reduced due to pulmonary and cardiac limitations. We investigated relationships between serum N-terminal of proB-type natriuretic peptide (NT-proBNP) and RV functions with exercise capacity and quality of life in patients COPD. Methods: An observational case-control study was conducted. We enrolled 31 moderate and severe COPD patients, and 20 subjects without chronic diseases as control group. Parameters reflecting the right ventricular diastolic and systolic functions by echocardiography along with serum NT-proBNP levels were assessed. Cardiopulmonary exercise testing and Short Form-36 (SF-36) were applied. Results: Serum NT-proBNP levels were higher in COPD patients than control group (p=0.003). Serum NT-proBNP level was found to be related with pulmonary arterial pressure. Serum NT-proBNP levels were negatively correlated with anaerobic threshold oxygen uptake (AT VO2) and peak oxygen uptake (PVO2) values. Early ventricular filling velocity (Em) was lower in COPD patients. Em wave was significantly correlated with O-2 pulse. There was a positive relationship between tricuspid E/A ratio and VO2 value at AT. SF-36 domains of physical functioning, general health and role limitation due to physical disorder were significantly correlated with AT VO2, PVO2 and O-2 pulse. Conclusion: Exercise limitation may be predicted by assessment of right ventricule functions and NT-proBNP levels and exercise limitation impairs quality of life in COPD patients.Item Is Clipping Superior to Cauterization in the Treatment of Palmar Hyperhidrosis?(2014) Findikcioglu, Alper; Kilic, Dalokay; Hatipoglu, Ahmet; 23839873Background Endoscopic thoracic sympathectomy has been accepted as the most effective treatment for palmar hyperhidrosis (PH). However, there is a debate regarding the surgical techniques in terms of effectiveness, recurrence, and reversibility. In this study, sympathetic chain disruptions were compared in terms of whether the clipping or ablation technique had an effect on the long-term outcomes of patients who underwent thoracic sympathectomy for primary PH. Patients and Methods All patients who underwent video-thoracoscopic sympathectomy for PH between May 2008 and October 2011 were included. Single-port bilateral sympathectomy was performed depending on the sweat distribution. As a standard approach, rib-based terminology was used to describe the blockade level of the sympathetic ganglia, and single-level R3 sympathectomy (between R3 and R4) was performed in all patients. The type of sympathectomy was changed. Monopolar electrocautery was first performed and 5-mm clips were then used for nerve disruption. Both techniques were evaluated and compared in terms of effectiveness, reversibility, and recurrence. Results Cauterization of the sympathetic chain was applied in 28 (47%) (Group A) patients and clipping in 32 (53%) patients (Group B). CH was the most common adverse effect and was observed in 43 (71.6%) patients (Group A, 71.4%; Group B, 71.8%; p = 0.8). The success rate was 93% for Group A and 100% for Group B (p = 0.15). The satisfaction rate for Group A was 83% and for Group B was 86% (p = 0.77). In Group A two patients (7%), and in Group B three patients (9%) requested reversibility because of severe compensatory hyperhidrosis. Overly dry hands were the other most common side effect and were identified in 12 (25%) patients. Recurrences were observed in 11 patients in Group A and 4 patients in Group B (19 vs. 6%; p = 0.01). The mean follow-up time was 33 +/- 10.5 months (range, 13-53 months). Conclusion Both clipping and cauterization are highly effective for the treatment of PH. The methods are comparable in terms of effectiveness and side effects despite the fact that the recurrence rate was higher in the cauterization group. Potential reversibility of compensatory sweating was not observed in our series. Identification of ideal candidates for surgery and education of patients about the permanent side effects of sympathectomy might make these techniques more convenient.Item Correlation Between Life Events and Quality of Life in Patients with Medication-Overuse Headache(2015) Altintas, Ebru; Goksel, Basak Karakurum; Taskintuna, Nilgun; Sariturk, Cagla; 28360716Introduction: The present study aimed to determine (a) the correlation between type and number of stressful life events and quality of life in patients with medication-overuse headache (MOH) and (b) whether stressful life events could be attributed to medication overuse and the conversion of headache to a chronic type. Methods: The present study included 114 patients aged between 15 and 65 years who met the criteria for headache classification of International Headache Society (IHS). The patients were divided into three groups according to the revised 2004 IHS classification; MOH (n= 64), chronic migraine (n=25) and episodic migraine (n=25). Detailed data on clinical and sociodemographic characteristics were recorded. Neurological and physical examinations were performed for differential diagnosis. The patients underwent structured clinical interviews for DSM-IV Inventory (SCID-I), Beck Anxiety Inventory, Beck Depression Inventory, Short Form-36 (SF-36) and Life Events List. Scores of these inventories were statistically compared. Results: Comparing MOH group with episodic migraine group via SF36, statistically significant decreases were observed in the subscales of physical role limitation (p=.024), pain (p=.0001), general health (p=.043) and social functioning (p=.004). There was a statistically significant correlation between the number of life events and the time the disease became chronic in the patient group with non-MOH chronic migraine (p=.027). Moreover, a statistically significant correlation was observed between stressful family life events and the body pain subscale of quality of life scale (p=.038). Conclusion: The present study demonstrates that stressful life events impair quality of life in patients with MOH. It was also found that number of stressful life events could be attributed to the conversion of headache to a chronic type.Item Psychiatric factors associated with normal coronary angiography among angina like chest pain patients(2016) Alttinbas, Ebru; Yiğit, FatmaPurpose: This psychiatric and cardiological study aim to compared patients with normal coronary angiography and coronary hearth disease patients with respect to sociodemografic features, psychiatric comorbidities, anxiety and depression level, mental and physical quality of life. We also determined associated factors with normal coronary patients. Material and Methods: Eighty-seven patients with normal coronary angiography (NCA) and thirty-one coronary artery disease (CAD) patients were included the study after coronary angiography. Groups were compared with regard to sociodemographic characteristics, comorbid psychiatric disorders and Beck Anxiety (BAI) and Beck Depression (BDI) Inventories and Health Related Quality of Life (SF-36) scale scores. Results: There was statistically significant difference between the groups in terms of age, gender, marital status, occupation, family history for psychiatric disorders. Mental disorders were found in 82.8% of the patients with NCA and in 48.1% of the patients with angiographic coronary disease. The patients with NCA have a higher prevalence of psychiatric comorbidity, family history of psychiatric disorder, are relatively young, female and unmarried. There was significant difference in pain, general health and social function subgroups of quality of life scale between groups. The impact of mental and physical quality of life with NCA patients were as significant as those with CAD. Conclusion: The present study revealed that prevalence of psychiatric co morbidities is high and impairment in quality of life is notable in the patients with NCA patients.