Wos İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4807
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Item Is There a Relationship Between Insulin Resistance and Breast Cancer-Related Lymphedema? A Preliminary Study(2021) Doruk Analan, Pinar; Kaya, Emine; 33761281Background: High blood insulin levels, insulin resistance (IR), and obesity are components of metabolic syndrome (MetS). The literature has indicated a high risk of breast cancer in patients with MetS. However, no studies have been conducted evaluating the relationship between breast cancer-related lymphedema (BCRL), one of the most frequently encountered postbreast cancer treatment conditions, and IR. Therefore, the aim of this study was to evaluate whether there is a relationship between BCRL and IR. Methods and Results: A total of 28 patients diagnosed with breast carcinoma were included in this preliminary study. Patients were divided into BCRL (n = 15; mean age: 55.2 +/- 11.2 years) and non-BCRL (control) groups (n = 13; mean age: 55.17 +/- 6.57 years). Body mass index (BMI), waist and hip circumference, and fasting blood glucose and blood insulin levels of all patients were recorded. The Homeostasis Model Assessment (HOMA) test was used for the calculation of IR measurement with a value of 2.5 taken as an indicator of IR. Parameters were compared between groups. BMI, waist circumference measurements, blood insulin, and HOMA-IR levels were statistically significantly higher in the BCRL group than the control group (p < 0.05). HOMA-IR values >2.5 were found in 14 patients in the BCRL group. In the control group, only three patients had IR based on HOMA-IR criteria (p = 0.000). Hip circumference measurements and fasting blood glucose levels were similar between the groups (p > 0.05). Conclusions: BCRL appears to be associated with waist circumference, fasting blood insulin level, and HOMA-IR levels. In routine clinical practice, evaluation of IR may be important in the follow-up of this patient population.Item BMI, Physical Activity, Sleep Quality, Eating Attitudes, Emotions: Which One is Affected by Mindful Eating?(2021) Kose, Gizem; Tayfur, MuhittinPresent study, it was aimed to examine the eating attitude and mindful eating status of students and to examine the change of mindful eating status' besides informing with nutrition course. The study was executed by 318 healthy students aged 18-45 years, randomly selected among students studying at Uskudar University between September 2015 and May 2016. In addition to a survey form containing personal and health information of the students, the Eating Attitudes Test (EAT-40) was conducted by Savasir and Erol, and the Mindful Eating Questionnare-30 (MEQ-30) scale conducted by Turkish Kose et al. The mean age of the participants was 21.56 +/- 3.82 year. The mean score of the participants' EAT-40 score was found to be 24.22 +/- 13.98 and the mean score of the MEQwas 98.11 +/- 13.81. As the EAT-40 scores decreased, MEQ scores increased, but this relationship was not statistically significant (p> 0.05). It has been shown that 28.9% of students have an eating disorder risk. There was no statistically significant difference between men's (23.33 +/- 15.60) and women's (24.48 +/- 13.50) mean EAT-40 scores (p>0.05). Overweight-obese group was found to be having higher EAT-40 scores than the other BMI classes (p <0.05). While the students' body weight and BMI increased, the risk of eating disorder increased (r = 0.112, p <0.05 and r = 0.139, p <0.05), and mindful eating decreased (p> 0.05). A significant relationship was found between weight, BMI and MEQ subscales (r =-0.252, p <0.01 and r =-0.208, p<0.01). As food preferences evaluated, 33.3% of students that is vegan, 26.4% of the students that have no food preference and 24.1% of the students that don't eat red meat were at risk of eating disorder (p <0.05). There was no statistically significant difference between the EAT-40 score groups according to walking status of the participants (p> 0.05). There was a statistically significant relationship between walking status and emotional eating that is one of MEQ subscales (r = -0.159, p <0.01). As having nutrition course, EAT-40 score decreased and the score of MEQ increased (p> 0.05). There was no statistically significant relationship between the level of taking the course and EAT-40, MEQ or the subscales of MEQ (p> 0.05). In sum, nutrition courses influence students' eating attitudes and mindful eating positively. In addition, gaining mindfulness of eating will be helping manage to weight status.Item Evaluation of clinical, endocrine and metabolic findings in obese children with and without hepatosteatosis(2021) Basarir, Gunce; Ozcabi, Bahar; Sayman, Ozden Aksu; Akay, Hatice Ozturkmen; Yildiz, Feyza M.; 34142516Objectives: Non-alcoholic fatty liver disease (NAFLD) is a common obesity-related comorbidity in childhood. In this study, we aimed to evaluate predictors of NAFLD by comparing clinical, endocrine and metabolic findings in obese children with and without hepatosteatosis. Methods: Two hundred and eight obese children aged 6-18 years were included. The patients were divided into group 1 (patients with NAFLD, n=94) and group 2 (patients without NAFLD, n=114). Anthropometric measurements, pubertal stage, lipid profiles, fasting glucose and insulin, homeostatic model of assessment for insulin resistance (HOMA-IR), uric acid, total bilirubin, alanine aminotransferase (ALT), blood urea nitrogen, thyroid-stimulating hormone and free thyroxine parameters were compared retrospectively. Results: The mean body weight, body mass index (BMI), height, tri-ponderal mass index (TMI), insulin, HOMA-IR, triglyceride, ALT and uric acid values were significantly higher, while high-density lipoprotein-cholesterol (HDL-C) values were significantly lower in group 1. The 70.7% of obese children with hepatosteatosis and 83.9% of those without hepatosteatosis were correctly estimated by parameters including age, gender, ALT, HDL-C, fasting insulin and uric acid values. Conclusions: Since obesity-associated hepatosteatosis induces various long-term metabolic impacts in children, early detection is of critical importance. Age, gender, TMI, BMI, ALT, HDL-C, fasting insulin and uric acid values may help to predict the risk of hepatosteatosis. Besides, we assessed whether TMI compared to BMI does not have a better utility in estimating obesity-induced hepatosteatosis in children. This is the first study to show the association between TMI and hepatosteatosis in children.Item Outcome of Gastric Fundus and Pylorus Botulinum Toxin A Injection in Obese Patients Class I-II with Normal Pyloric Orifice Structure: A Retrospective Analysis(2021) Ferhatoglu, Murat Ferhat; Kartal, Abdulcabar; Filiz, Ali Ilker; Kebudi, AbutBackground: Any deterioration in pyloric muscle activity has the potential to influence gastric emptying. In such a case, gastric emptying time would also be changed due to the paralysis of pyloric muscles, which is the botulinum toxin's effect mechanism. This study aimed to investigate how the pyloric orifice structure influences the success of intragastric botulinum toxin type A injection (GBI) therapy in Class I-II obese patients for weight loss.Methods: The GBI applied patients were categorized according to pyloric orifice structure during upper gastrointestinal system endoscopy: Group A: the patients whose pylorus had normal peristaltic activity and closed completely and Group B: the patients whose pylorus did not close properly or were nonperistaltic. We measured the body mass index (BMI) of the patients before and 6 months after the procedure and expressed postprocedure weight loss in terms of the percentage of excess BMI (E-BMI%) loss. We compared preprocedure and sixth-month BMI and E-BMI% values. We applied the Student's t-test to analyze the differences among study groups, and p < 0.05 was accepted as statistically significant.Results: Seventy-seven patients completed the 6-month follow-up period. The measurements without considering the pyloric orifice structure showed that the mean BMI decrease in female patients (from 36.4 +/- 5.4 to 32 +/- 7.2 kg/m(2)) was significant (p < 0.05). And the BMI and E-BMI% loss in Group A were statistically significant (p < 0.05).Conclusion: We advise being selective and applying GBI to class I-II obese patients with normal pyloric orifice structure.Item Is Body Adiposity Index a Better and Easily Applicable Measure for Determination of Body Fat?(2020) Yesil, Esen; Kose, Beril; Ozdemir, Merve; 32155104Objective: The BAI can be used to reflect %body fat. This study aimed to compare BAI with other methods used in the determination of body fat. Materials and Methods: A cross-sectional study was conducted in Turkish adults. BAI, BMI, WHR, WHtR, body weight, hip and waist circumference (WC), skinfold thicknesses (biceps, triceps, subscapular, suprailiac) were measured. Body fat was measured using Bioelectric Impedance Analysis. Results: The Bland-Altman analyses conducted in this study showed that for % body fat estimations, BIA was in excellent agreement with skinfold measurements (p = 0.131) without proportional bias (p = 0.082), but that BAI was not in agreement with BIA and skinfold measurement. There were a statistically significant positive correlation between BAI and other measurements in terms of females and males and also regardless of sex. Conclusion: BAI was not in agreement with BIA and skinfold measurement methods for % body fat estimations, it had a significantly stronger correlation with % fat calculated using BIA and skinfold thickness.Item Effects of reproductive and sociodemographic factors on obesity in Turkish women: a pilot study(2019) Bayram, Sinem; Koseler, Esra; Kiziltan, Gul; Ok, Mebtap Akcil; Yesil, Esen; Kose, Beril; Ozdemir, Merve; Muftuoglu, Selen; Saka, Mendane; Aksoydan, Emine; Tayfur, Muhittin; Turker, Perim Fatma; Ercan, Aydan; 0000-0003-1569-7747; 0000-0002-4254-3711; AAF-4491-2021; AAG-6763-2020Background and aim: Obesity has become a global epidemic. The current research aimed to determine sociodemographic and reproductive predictors of obesity among Turkish women. Materials and methods: Eligible subjects (n:833) were 40-64 years-old women living in Turkey. A questionnaire consisted of questions about sociodemographic and reproductive factors and the International Physical Activity Questionnaire were applied to participants by face to face interviews. Multivariate logistic regression examined the risk of being obese with a range of sociodemographic and reproductive factors. All analyses were performed with SPSS software (version 17.0; SPSS, Chicago, Ill., USA). Results: The mean BMI of women aged 51-64 years was 30.59 +/- 6.35 kg/m(2). After adjustments for all other variables, increased obesity risk remained significant in women who had two children, housewifes, minimum active ones, ex smokers and had less than high school education. For multiple regression analysis sociodemographic factors from the bivariate analyses were entered, controlling for menarch age, menopausal age, hormone RT, parity, number of stillbirth, abortion. There was significant association between family income, occupation, education and BMI. Conclusion. In summary these findings showed comparable patterns of association of sociodemographic and reproductive factors with obesity in Turkey. Specific healthy lifestyle counseling is important for decreasing obesity in childbearing age women.Item Comparison of obese and non-obese patients in terms of self-esteem, body perception, body weight perception and sociodemographic components(2019) Engur, Sevgi; Karagol, ArdaObjective: The aim of the study is to compare the randomly selected obese patients from the endocrinology outpatient clinic of a university hospital and the randomly selected non-obese patients from the general internal diseases outpatient clinic of the same hospital in the sense of self-esteem, body perception, body weight perception and some other sociodemographic features. Methods: The study included a total of 350 patients, of whom 175 were obese (147 female patients, 84%) and 175 were non-obese (115 female patients, 65.7%). The body mass indexes of the patients who were included in the study were measured. While the Rosenberg Self Esteem Scale was used to assess self-esteem, the body perception scale was used to assess the body perception of these patients. The consistency between the body mass index classifications and the self-body weight perceptions of the patients was also assessed. Results: The obese patients were found to have lower self-esteem and be less pleased about their bodies, and tend to perceive their body weights lower than their actual body weight when compared with the non-obese group. The non-obese patients in our study were found to be more pleased about their bodies whereas they showed higher levels of self-esteem and perceived their body weights more accurately. Discussion: In the light of these findings, obese patients should be evaluated in terms of psychiatry and get psychiatric help if needed. Eventually, obesity is an important issue which should be addressed multidisciplinary.