Wos İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4807
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Item Effects of Renal Transplantation and Hemodialysis on Patient's General Health Perception and Oral Health-Related Quality of Life: A Single-Center Cross-Sectional Study(2020) Oduncuoglu, Bahar Fusun; Alaaddinoglu, Emine Elif; Colak, Turan; Akdur, Aydincan; Haberal, Mehmet; 0000-0002-8726-3369; 0000-0002-8372-7840; 0000-0002-3462-7632; 0000-0003-0647-9481; 32113695; AAA-3068-2021; AAJ-8554-2021; AAJ-8097-2021; AAQ-4792-2020Background. Patients with end-stage renal disease have a lower quality of life compared to the general population. Oral health-related quality of life (OHRQoL) is of particular interest as good oral health could influence general health. This study aimed to compare dental and periodontal health status, OHRQoL, and general health perception of renal transplant (TX) and hemodialysis patients (HD) with that of healthy controls. Methods. The study included 64 TX, 63 HD, and 61 healthy patients. TX patients were also grouped according to the time elapsed after transplantation and currently use of immunosuppressive agents. The numbers of decayed, missing, and filled teeth were recorded as DMFT, and periodontal health status was evaluated. Patients' general health perceptions and OHRQoL were assessed using Short Form-36, Oral Health Impact Profile-14, and OHRQoL-United Kingdom questionnaires. Results. The HD groups presented significantly higher DMFT scores and periodontal scores than TX and control groups. OHRQoL-United Kingdom total scores of TX and HD groups were lower than controls (P < .05). Oral Health Impact Profile-14 total scores revealed that HD groups' OHRQoL was significantly lower than TX and control groups (P < .05). Perceptions of general health of TX patients were higher than in the HD group. Conclusions. Renal transplantation has shown to increase quality of life and OHRQoL compared to hemodialysis therapy. Neither the immunosuppressive agent nor the time elapsed after transplantation were observed to be significant factors affecting OHRQoL.Item Wage inequality, skill-specific unemployment and trade liberalization(2020) Koymen-Ozer, SedaLabour market outcomes of trade liberalization are at the heart of the policy debate. In this model, the long-run effects of trade liberalization and trade-induced skill-biased technological change on wage inequality and unemployment are studied by augmenting a heterogeneous firm trade model with job search and unemployment. In the model, there are two types of workers-skilledandunskilled-and two types of technologies-lowandhigh. Firms draw their productivities from a common distribution and, conditional on their productivity, decide on the entry, export and type of technology. Then they post the optimal number of vacancies and engage in individual wage bargaining with workers. In the case of two symmetric partners, trade liberalization leads more firms to enter foreign markets while leading the least-productive firms to exit. Moreover, with lower technology-adoption costs and/or a higher initial level of liberalization, more firms upgrade their technology after a reduction in variable trade cost. The redistribution of market shares toward more-productive firms increases the demand for both skilled and unskilled workers. This, in turn, raises wages and reduces unemployment rates for both types of workers. Nevertheless, trade liberalization has asymmetric wage effects on workers: it increases wage inequality in favour of skilled workers. Further, the unemployment rate in the skilled labour market falls to a greater extent, implying a change in the skill composition of unemployed workers in both trade partners. Resume Inegalite salariale, chomage lie aux competences specialisees et liberalisation. Les consequences de la liberalisation des echanges sur le marche du travail sont au c oe ur du debat politique. Dans ce modele, nous etudions les effets a long terme de la liberalisation des echanges et des evolutions technologiques induites par le commerce, lesquelles favorisant les competences specialisees, a la fois sur les inegalites salariales et le chomage. A cette fin, nous avons augmente un modele commercial d'entreprises heterogenes en y ajoutant la recherche d'emploi et l'inactivite professionnelle. Dans ce modele, nous nous appuyons sur deux types de travailleurs, les travailleurs qualifies et non qualifies, et sur deux types de technologies, les technologies rudimentaires et les hautes technologies. Les entreprises tirent leur productivite d'une distribution commune, et en fonction de cette meme productivite, peuvent decider de l'introduction, de l'exportation et du type de technologie. Ensuite, ces entreprises proposent un nombre optimal d'emplois a pourvoir et s'engagent dans une negociation salariale individuelle avec les travailleurs. Dans le cas de deux partenaires symetriques, la liberalisation des echanges conduit davantage d'entreprises a integrer les marches etrangers tout en poussant les moins productives a en sortir. De plus, avec des couts d'adoption technologiques plus faibles et/ou avec un niveau de liberalisation initial plus eleve, de plus en plus d'entreprises modernisent leur technologie apres avoir reduit leurs couts commerciaux variables. La redistribution des parts de marche vers les entreprises les plus productives provoque une augmentation de la demande de travailleurs qualifies et non qualifies. Par voie de consequence, les salaires augmentent et le taux de chomage diminue pour les deux types de travailleurs. Neanmoins, la liberalisation des echanges engendre un effet asymetrique quant au salaire des travailleurs car elle augmente les inegalites salariales en faveur des travailleurs les plus qualifies. De plus, le taux de chomage des travailleurs qualifies diminue bien davantage, modifiant ainsi la composition des competences de la main d'oe uvre des travailleurs sans emploi pour les deux partenaires commerciaux.Item Evaluation of quality of life after implantation of a new trifocal intraocular lens(2019) Akman, Ahmet; Asena, Leyla; Ozturk, Caner; Gungor, Sirel Gur; 0000-0001-6178-8362; 0000-0002-6848-203X; 30612749; E-5914-2016; AAD-5967-2021Purpose: To evaluate the vision-related quality of life (QOL) after implantation of a new trifocal intraocular lens (IOL), by using the National Eye Institute Visual Function Questionnaire-14 (VF-14 QOL questionnaire). Setting: Baskent University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey. Design: Prospective noncomparative case series. Methods: Consecutive patients who had a new trifocal IOL (Pan-Optix) bilaterally implanted were included in the study. The vision-related QOL was assessed 3 months after the surgery in the second eye. The VF-14 QOL questionnaire was used, with a grading scale of 0, no difficulty; 1, a little difficulty; 2, moderate difficulty; 3, quite difficult; 4, impossible to perform. A subgroup of 14 patients, with an interval of at least 3 months between the surgery in the first eye and the surgery in the fellow eye, were also interviewed 3 months after the monocular IOL implantation. In this subgroup, the QOL with monocular and binocular implantation was compared. Results: The study comprised 48 patients. Reading small print, driving at night, and doing fine handwork were the most difficult tasks to perform, with the mean values of the VF-14 QOL questionnaire being 0.94 +/- 0.81 (SD), 0.89 +/- 0.68, and 0.64 +/- 0.67, respectively. Binocular implantation was associated with improvement in vision-related QOL when compared with monocular implantation, with significant differences in doing fine handwork such as sewing (P = .02) and using a computer (P = .03). Conclusions: With mean values of 1.00 or lower for each question, the results of the VF-14 QOL questionnaire indicated that patients who have the new trifocal IOL bilaterally implanted have an overall high satisfaction rate and a high vision-related QOL. (C) 2018 ASCRS and ESCRSItem Prognostic significance of lymphovascular space invasion in low-risk endometrial cancer(2019) Ayhan, Ali; Sahin, Hanifi; Sari, Mustafa Erkan; Yalcin, Ibrahim; Haberal, Ali; Meydanli, Mehmet Mutlu; 30665899Objective The purpose of this study was to assess the prognostic significance of lymphovascular space invasion in women with low-risk endometrial cancer. Methods A dual-institutional, retrospective department database review was performed to identify patients with 'low-risk endometrial cancer' (patients having <50% myometrial invasion with grade 1 or 2 endometrioid endometrial cancer according to their final pathology reports) at two gynecologic oncology centers in Ankara, Turkey. Demographic, clinicopathological and survival data were collected. Results We identified 912 women with low-risk endometrial cancer; 53 patients (5.8%) had lymphovascular space invasion. When compared with lymphovascular space invasion-negative patients, lymphovascular space invasion-positive patients were more likely to have post-operative grade 2 disease (p<0.001), deeper myometrial invasion (p=0.003), and larger tumor size (p=0.005). Patients with lymphovascular space invasion were more likely to receive adjuvant therapy when compared with lymphovascular space invasion-negative women (11/53 vs 12/859, respectively; p<0.001). The 5-year recurrence-free survival rate for lymphovascular space invasion-positive women was 85.5% compared with 97.0% for lymphovascular space invasion-negative women (p<0.001). The 5-year overall survival rate for lymphovascular space invasion-positive women was significantly lower than that of lymphovascular space invasion-negative women (88.2% vs 98.5%, respectively; p<0.001). Age >= 60 years (HR 3.13, 95% CI 1.13 to 8.63; p=0.02) and positive lymphovascular space invasion status (HR 6.68, 95% CI 1.60 to 27.88; p=0.009) were identified as independent prognostic factors for decreased overall survival. Conclusions Age >= 60 years and positive lymphovascular space invasion status appear to be important prognostic parameters in patients with low-risk endometrial cancer who have undergone complete surgical staging procedures including pelvic and para-aortic lymphadenectomy. Lymphovascular space invasion seems to be associated with an adverse prognosis in women with low-risk endometrial cancer; this merits further assessment on a larger scale with standardization of the lymphovascular space invasion in terms of presence/absence and quantity.