Wos İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/11727/4807

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Author: search.filters.author.Ozcan, Derensearch.filters.applied.f.language: search.filters.language.eng

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    Pediatric Androgenetic Alopecia: A Retrospective Review Of Clinical Characteristics, Hormonal Assays And Metabolic Syndrome Risk Factors In 23 Patients
    (2022) Ozcan, Deren; https://orcid.org/0000-0002-7450-6886; 35033390; AAQ-6649-2021
    Background: Androgenetic alopecia in the pediatric population is rarely discussed in the literature. Although the prevalence of the metabolic syndrome is increased in patients with early-onset androgenetic alopecia, the presence of metabolic syndrome risk factors in pediatric androgenetic alopecia is unknown. Objective: To evaluate the demographics, medical and family histories, clinical and trichoscopic features, androgenic hormones, and metabolic syndrome risk factors in pediatric androgenetic alopecia. Methods: The medical reports of pediatric patients with androgenetic alopecia were reviewed. Results: The study included 23 patients (12 females and 11 males) with a mean age of 15,3 +/- 2,1 years. Sixteen patients had adolescent androgenetic alopecia and seven, had childhood alopecia. Nine patients reported a family history, all of whom had adolescent androgenetic alopecia. Hyperandrogenism was noted in three patients with adolescent androgenetic alopecia. The most common hair loss pattern was diffuse thinning at the crown with preservation of the frontal hairline which was noted in 10 patients (43.5%), six of whom were males. Fourteen patients (60.9%) had at least one metabolic syndrome risk factor. The most common risk factor was obesity or overweight (47.8%) followed by insulin resistance (21.7%), high fasting blood glucose (13%), high blood pressure (4.4%) and lipid abnormalities (4.4%). Study limitations: Retrospective study; lack of a control group. Conclusion: Pediatric androgenetic alopecia is often associated with metabolic syndrome risk factors. Therefore, androgenetic alopecia in the pediatric population may indicate a future metabolic syndrome which warrants an accurate and prompt diagnosis for early screening and treatment. (C) 2021 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
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    Comparison of 10 versus 20 sessions tap water iontophoresis efficacy in the treatment of palmoplantar hyperhidrosis
    (2022) Vural, Ayse Tuncer; Ozcan, Deren; Gulec, Ayse Tulin; https://orcid.org/0000-0001-8770-5721; 34982502; AAQ-4123-2021
    Background Tap water iontophoresis (TWI) is an effective treatment option for palmoplantar hyperhidrosis (HH). However, the optimal number and frequency of TWI sessions to control profuse sweating are unclear. Objective To compare the efficacy of 10 and 20 sessions of TWI in patients with palmoplantar HH and determine the adequate number of sessions to achieve a favorable clinical response. Methods Eighty patients treated with TWI for palmoplantar HH were included. The alteration in sweating intensity considering the mean value of gravimetric measurement and mean visual analog scale (VAS) scores after the 10th and 20th session of TWI were calculated. The difference between performing 10 and 20 sessions of TWI in providing improvement of HH was analyzed. We also conducted a telephone-based inquiry to determine the patients' outcome. Results The reduction in sweating intensity was significant both after the 10th (p < 0.001) and 20th (p < 0.001) sessions when compared with the basal level considering gravimetry and VAS. When the mean sweating intensity after the 10th and 20th sessions were compared, no difference was observed gravimetrically (p = 0.03); the difference between the mean score of VAS after the 10th and 20th sessions (p < 0.001) was significant. Eleven and nine patients not considering a maintenance or an alternative treatment had lower and same sweating intensity as compared with the baseline, respectively. Conclusion Ten TWI sessions within two weeks for managing palmoplantar HH are adequate to achieve a clinical response. However, the patients are more satisfied when they receive 20 sessions instead of 10 sessions of TWI.
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    N-Acetylcysteine for Managing Neurotic Excoriation: Encouraging Results in Two Patients
    (2021) Ozcan, Deren; 0000-0002-7450-6886; 33781651; AAQ-6649-2021
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    Two cases of fibrosing alopecia in a patterned distribution after coronavirus disease 2019
    (2021) Ozcan, Deren; Vural, Ayse Tuncer; Ozen, Ozlem; 0000-0002-7450-6886; 0000-0001-8770-5721; 34491674; AAQ-6649-2021; AAQ-4123-2021
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    Adult Still's disease: An unusual case with atypical skin and histopathological findings
    (2020) Vural, Ayse Tuncer; Ozcan, Deren; Tepeoglu, Merih; 0000-0002-9894-8005; AAK-5222-2021
    Adult Still's disease is a rare, acute systemic inflammatory disease characterized by a sudden rising fever, arthralgia/arthritis, neutrophilic leukocytosis and a typical salmon-colored macular or maculopapular rash associated elevated fever. Recently, atypical skin lesions with broad spectrum clinical features and distinctive histopathological findings have been reported in a rare case with active disease. Herein, we report an unusual case of Adult Still disease was presented and the characteristic features of atypical disease were highlighted.
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    Platelet-rich plasma for treatment resistant frontal fibrosing alopecia: A case report
    (2019) Ozcan, Deren; Vural, Ayse Tuncer; Ozen, Ozlem; 0000-0002-7450-6886; 31443128