Wos İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11727/4807
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Item Comparison of Epicardial Fat, Carotid and Femoral Intima-Media Thicknesses Between Hypertensive, Pre-Hypertensive and Control Groups(2020) Gunesli, Aylin; Yilmaz, Mustafa; 0000-0002-2557-9579; S-6973-2016Objective: The aim of this study was to evaluate whether pre-hypertension is a risk factor for cardiovascular events. For this reason epicardial fat thickness (EFT), carotid intima-media thickness (CIMT) and femoral intima-media thickness (FIMT), known as markers for subclinical atherosclerosis and cardiovascular risks were measured and compared among the pre-hypertensive, hypertensive and control groups. Material and methods: This cross-sectional study included 57 healthy controls (group 1), 58 pre-hypertensive patients (group 2) and 56 hypertensive patients (group 3). Pre-hypertension is defined as systolic blood pressure (SBP) 120-140 mm Hg and diastolic blood pressure (DBP) 80-90 mm Hg. Hypertension is defined as SBP>140 mm Hg and/or DBP>90 mm Hg. EFT, CIMT and FIMT were measured and compared among these groups. Results: There was a statistically significant difference among the groups in terms of EFT and CIMT (p<0.001, for both comparison). In addition there was a statistically significant difference between groups 2 and 1, and between groups 3 and 2 in terms of EFT and CIMT (p<0.001, for all comparisons). When we compared the all groups in terms of FIMT, we found a statistically significant difference (p<0.001). There was a statistically significant difference between groups 3 and 2 (p=0.001). However, there was not a statistically significant difference between groups 2 and 1 (p=0.773). Conclusion: These results may indirectly suggest that subclinical atherosclerosis and cardiovascular risks may be increased in pre-hypertensive patients. However, atherosclerosis in the carotid arteries may be affected by lower blood pressure than the femoral arteries.Item Assessment of Carotid Artery Distensibility and Elasticity After Laparoscopic Sleeve Gastrectomy: a Prospective Study(2020) Gunesli, Aylin; Yilmaz, Mustafa; Altin, Cihan; Gezmis, Esin; Yabanoglu, Hakan; Erol, Varlik; 0000-0002-2557-9579; 0000-0002-8337-6905; 0000-0002-1161-3369; 0000-0002-1001-6028; 0000-0003-0268-8999; 32813160; S-6973-2016; AAK-3065-2021; AAJ-7865-2021; AAE-8301-2021; AAK-2011-2021Purpose Although it is well known that obesity increases the risk of atherosclerosis in carotid arteries, it is not clear whether this risk changes after obesity surgery. The aim of this study was to investigate whether weight reduction with a laparoscopic sleeve gastrectomy (LSG) has any effect on distensibility and elasticity which show subclinical atherosclerosis in the carotid arteries of obese individuals. Materials and Methods This prospective study included 130 patients (body mass index (BMI) 48.21 +/- 6.97 kg/m(2)) who underwent LSG. The patients were followed up for 1 year. Comparisons were made of the distensibiliy and elasticity values calculated preoperatively and at 1, 3, 6, and 12 months, postoperatively. Results There was a statistically significant increase in distensibility and elasticity values from baseline to 1, 3, 6, and 12 months postoperatively (p < 0.001 for both comparisons). The multiple linear regression analysis was used to find the variables affecting both distensibility and elasticity. According to the results, the presence of BMI decreases distensibility percentage change level by 0.38 units (beta= - 0.38, 95% CI - 0.51;- 0.25,p < 0.001). The presence of fasting plasma glucose decreases elasticity percentage change level by 0.20 units. (beta= - 0.20, 95% CI - 0.39; - 0.01,p = 0.037). Conclusion Carotid artery distensibility and elasticity values increase after LSG, and this change could be caused by the change in metabolic parameters and heart geometry. These results may indirectly suggest that subclinical atherosclerosis in carotid arteries has decreased after obesity surgery.