Browsing by Author "Yurdakul, Pinar"

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    The Effect of Different Polishing Sequences on the Adhesion of Streptococcus mutans to Feldspathic Porcelain
    (2016) Yuzugullu, Bulem; Celik, Cigdem; Ozcelik, Tuncer Burak; Erkut, Selim; Yurdakul, Pinar; Ocal, Yesim; Sener, Burcin; https://orcid.org/0000-0002-5936-0196; AAA-1576-2021
    The aim of this research was to determine whether extra-oral surface treatments on feldspathic porcelain surfaces influence initial adhesion of Streptococcus mutans. Ninety-six porcelain specimen discs were fabricated and divided into six equal groups according to surface treatment: fine-grit diamond polishing (Group 1); self-glazing (Group 2); overglazing (Group 3); overglazing followed by a finishing procedure and then overglazing (Group 4); Pearl Surface polishing (Group 5); and Diamond Twist SCLTM polishing (Group 6). Surface roughness and hydrophobicity were assessed. An S. mutans suspension was incubated on each specimen group and evaluated. A one-way analysis of variance, post-hoc Tukey honestly significantly different test, Friedman test, and t-test were used for statistical analysis. Group 1 showed the highest surface roughness (p < 0.001) and bacterial adhesion (p < 0.05). Groups 5 and 6 specimen surfaces presented significantly higher contact angles (p < 0.05). Group 1 had the highest S. mutans adhesion, followed by Groups 3, 5, 6, 2, and 4 (p < 0.05). Reglazing after grinding may therefore decrease bacterial adhesion beneficially.
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    Molecular Methods for Detection of Invasive Fungal Infections and Mycobacteria and Their Clinical Significance in Hematopoietic Stem Cell Transplantation
    (2014) Yurdakul, Pinar; Colakoglu, Sule; 24473787
    Infection remains an important source of morbidity and mortality in patients who undergo hematopoietic stem cell transplantation (HSCT). In the immune reconstitution period after transplantation, HSCT recipients are most likely to have bacterial or fungal infections. Invasive fungal infections (IFIs) and mycobacterial infections (MBIs) are among the complications of HSCT, with high morbidity and mortality rates. Early diagnosis of both is crucial in order to manipulate the disease and to avoid fulminant outcomes. This chapter reviews the current knowledge on the molecular diagnosis of IFIs and MBIs in HSCT recipients, describing two different polymerase chain reaction (PCR)-based methods, one commercial (qPCR, Roche) and one in-house IS6110-based protocol.