Browsing by Author "Yilmaz, Murat"

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The Correlation of TWEAK Level And with Involved Area on MRI in Stroke
(2017) Yilmaz, Muhittin Serkan; Yilmaz, Murat; Isik, Bahattin; Yel, Cihat; Kavalci, Cemil; Demirci, Burak; Inan, Selim; Kavak, Rasime Pelin; Balamir, Ilhan; Turhan, Turan; 0000-0003-2529-2946; 0000-0001-6658-7260; AGG-1308-2022; AAD-2829-2021; ABG-1934-2020
The aim of this study was to value of TWEAK protein in stroke diagnosis and the correlation between Tweak level and lesion size on diffusion MRI in patients admitted to emergency department for acute stroke. Our study was prospectively conducted in a group of patients diagnosed with stroke in the emergency department and a control group between 1 June 2014 and 31 August 2014. Age, sex, vital parameters, comorbid conditions, neurological deficit level, Tweak level, and involved volume on D-MRI were analyzed. Age, sex, vital parameters, comorbid conditions, and Tweak levels were compared between the patient and control groups. Tweak level was compared with neurological deficit and diffusion on D-MRI imaging in the patient group. The results were evaluated in a confidence interval of 95% and at a significance level of p<0.05. There were no significant differences between both groups with respect to age and sex distribution. The median Tweak level of the patient group was significantly higher (912.1 pg/ml vs 808.3 pg/ml, p<0.05). In the patient group NIHSS score had a positive correlation to MRI lesion size (p<0.05) but not to Tweak level (p>0.05). There was no correlation between Tweak level and the involved area on diffusion MRI (p>0.05). In conclusion, Tweak appears as a parameter that can be used in patients with a clinical presentation consistent with Stroke. It can be used for diagnostic purposes when cranial CT does not support the diagnosis or for supporting diagnosis when D-MRI is not available.
Left-Sided Atrial Septal Pouch and Risk of Cryptogenic Stroke
(2016) Yilmaz, Murat; Vural, Mustafa Gokhan; Karcaaltincaba, Musturay; Yoldas, Tahir Kurtulus; Yilmaz, Muhittin Serkan; Kavalci, Cemil; https://orcid.org/0000-0003-2529-2946; AGG-1308-2022
Introduction: Stroke is the second most cause of death worldwide after coronary artery disease. Left-sided atrial septal pouch (LASP) is associated with potential cardioembolic stroke. This study determines the association between LASP and cryptogenic stroke (CS) using cardiac multi-detector computed tomography (cMDCT) angiograms. Materials and methods: This study included 40 patients with CS (23 males, mean age: 403 +/- 10.4 years) and 40 age- and sex matched healthy controls. cMDCT examinations by dual-source 64-slice MDCT with 0.6-mm slice thickness were performed for all patients and controls. The association between LASP and risk of CS was assessed after adjustment for other stroke risk factors. Results: Patients with LASP were younger than control subjects (41.3 +/- 7.2 years vs 44.2 +/- 5.7 years; p = 0.066), with a comparable prevalence of hypertension (42.5% vs 35%; p = 0.491) and other risk factors. There were no differences in the prevalence of LASP between patients and controls (32.5% vs 25%; p = 0.621). LASP was observed in 43.5% (n = 10) of normotensive stroke patients compared to 15.4% (n = 4) of normotensive controls (Odds Ratio (OR): 4.23, 95% CI: 1.09-16.27, p = 0.063). On the other hand, LASP was detected in 17.6% (n = 3) of hypertensive CS patients compared to 42.9% (n = 6) of hypertensive controls (OR: 028, 95% CI: 0.05-4.23, p = 0.253). The presence of LASP was not associated with an increased risk of CS. Conclusion: This study suggests that LASP is associated with CS. However, in normotensive individuals, LASP may be a minor risk factor for CS.
Management of Humoral Rejection in Renal Transplantation: Results of A Single Center
(2016) Ayvazoglu, Ebru H.; Kirnap, Mahir; Yilmaz, Murat; Moray, Gokhan; https://orcid.org/0000-0002-0993-9917; https://orcid.org/0000-0003-2498-7287; AAC-5566-2019; AAH-9198-2019; AAE-1041-2021