Browsing by Author "Yilmaz, Alev"

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Camouflage Treatment of a Severe Open Bite Case
(2014) Yilmaz, Alev; Arman-Ozcirpici, Ayca
Comparison of short-term effects of mini-implant-supported maxillary expansion appliance with two conventional expansion protocols
(2015) Yilmaz, Alev; Arman-Ozcirpici, Aya; Erken, Seda; Polat-Ozsoy, Omur; 25564504
Objective: This study evaluates the dentoskeletal effects of a mini-implant-supported maxillary expansion (MISME) appliance in comparison with two types of conventional expansion methods. Methods: Records of 42 patients with bilateral or unilateral posterior crossbite were included in this study. The patients were divided into three groups. In group 1, four miniscrews were placed to the palatal region and an acrylic expansion device was bonded on these screws. A bonded maxillary expansion appliance was used in group 2, while a banded expansion appliance was used in group 3. Measurements from cephalometric, postero-anterior radiographs, and dental casts taken before and after expansion were evaluated statistically. Results: ANB angle increased significantly in group 1 and 3. MISME group also showed an increase of SNA angle. Measurements regarding the vertical dimension did not change with MISME but significant posterior rotation was found in group 2 and 3. Overbite value showed a significant decrease in group 2 and 3, but remained stable in group 1. The nasal, maxillary, maxillary intermolar widths showed significant increases in all groups. The difference between MISME group and other groups in maxillary width was significant indicating more skeletal expansion in MISME group. The maxillary molars showed significant buccal tipping in group 2 and 3, while lingual tipping of molars was found in MISME group. Conclusions: MISME can be a better alternative to bonded expansion particularly in patients with vertical growth patterns and lack of anchorage teeth.
Eculizumab treatment and discontinuation in pediatric patients with atypical hemolytic uremic syndrome: a multicentric retrospective study
(2022) Baskin, Esra; Fidan, Kibriya; Gulhan, Bora; Gulleroglu, Kaan; Canpolat, Nur; Yilmaz, Alev; Parmakiz, Gonul; Ozcakar, Birsin Z.; Ozaltin, Fatih; Soylemezoglu, Oguz; 35060104
Introduction Eculizumab is effective treatment of pediatric atypical hemolytic uremic syndrome (aHUS). However, the optimal duration of treatment is not clearly defined. The aim of this study was to retrospectively analyze the outcome of pediatric patients with aHUS, who started eculizumab treatment but discontinued it during the follow-up period. Methods The clinical and laboratory findings of the pediatric patients with aHUS were recorded on a web-based, national registry system, known as the Turkish aHUS Registry. The study included 63 patients who had to have received more than four doses of eculizumab during the acute phase of the disease. Results The median age at diagnosis was 3.62 (IQR: 1.29-6.14) years. During the follow-up period, 39 patients continued to receive standard eculizumab treatment (standard treatment group, treatment every 2 weeks) while 24 received an extended dose of eculizumab at three-four-week intervals (non-standard treatment group). There was no significant difference between both groups in terms of clinical and laboratory parameters. Eculizumab treatment was discontinued in 18 patients (30.7%, F/M:11/7), and the median age of these patients at diagnosis and their median follow-up duration were 4.0 (IQR:2.7-10.2) and 4.2 (IQR:2.2-7) years respectively. The median eGFR at the last visit was 110 (84.7-146.1)ml/min/1.73 m(2). Fourteen patients remained in remission without any sign of the disease. Recurrence occurred in four (22.2%) patients, in which eculizumab was immediately started again and complete remission was achieved. Conclusion Eculizumab is a successful treatment option in pediatric patients with aHUS and it can be safely discontinued with close monitoring in a selected group of patients. In case of recurrence, eculizumab should be restarted immediately to achieve complete remission. [GRAPHICS] .
Evaluation Of Patients With Primary Hyperoxaluria Type 1: A Multicenter Study
(2018) Bakkaloglu, Sevcan A.; Buyykkaragoz, Bahar; Saygili, Seha; Comak, Elif; Yildirim, Zeynep Y.; Akinci, Nurver; Bayazit, Aysun Karabay; Tufan, Asli Kavaz; Akman, Sema; Yilmaz, Alev; Dursun, Ismail; Noyan, Aytul; Agbas, Ayse; Serdaroglu, Erkin; Delibas, Ali; Elmaci, Ahmet Midhat; Tasdemir, Mehmet; Sever, Lale; AAD-5713-2021
Maxillary Expansion Via Palatal Mini-Implants: A Preliminary Study
(2014) Arman-Ozcirpici, Ayca; Yilmaz, Alev; Polat-Ozsoy, Omur
Objective: This study evaluates the skeletal and dental effects of a mini-implant supported maxillary expansion (MISME) appliance that applied forces directly to the maxilla. Materials and Method: Records of 9 patients (5 female and 4 male patients; mean age = 12 years 8 months) with indications of maxillary expansion were included in this study. After insertion of four miniscrews (1.6 mm in diameter, 7 mm in length), an acrylic expansion device was bonded on the screws. Two miniscrews were placed in the anterior palate bilaterally, 3-4 mm lateral to the suture and 3-4 mm posterior to the incisive foramen. Two miniscrews were placed bilaterally between the second premolar and first molar roots in the palatal alveolus. The MISME appliance was activated with a semi-rapid protocol until the desired expansion was achieved. The average treatment duration was 97.1 +/- 62.2 days. Measurements from cephalometric, posteroanterior radiographs and dental casts taken before and after expansion were evaluated statistically. The nonparametric Wilcoxon test was used for not normally distributed parameters (i.e., Nperp-A), and the parametric paired t test was performed for normally distributed parameters. A finding of p < 0.05 was considered to be statistically significant. Results: Forward movement of the maxilla (p<0.05) as well as an increase in nasal and maxillary skeletal and dental widths (p<0.001) were observed in the sample group. Maxillary intermolar, intercanine, and palatal widths also increased (p<0.001) without buccal tipping of molars. A slight posterior rotation of the mandible was seen. Dentoalveolar measurements did not show any significant changes. Conclusion: The MISME appliance showed successful expansion of the maxilla without such side effects as buccal tipping of molars and bite opening. This appliance, which provides parallel expansion, can be a simple and economic alternative to transpalatal distraction.
Results of Turkish Multicentric National Cystinosis Registry
(2015) Topaloglu, Rezan; Gulhan, Bora; Ozaltin, Fatih; Bodur, Ilknur; Besbas, Nesrin; Dursun, Hasan; Yilmaz, Alev; Gurgoze, Metin Kaya; Gokce, Ibrahim; Akinci, Nurver; Erdogan, Ozlem; Dursun, Ismail; Canpolat, Nur; Donmez, Osman; Cayci, Fatma Semsa; Serdaroglu, Erkin; Comak, Elif; Nalcacioglu, Hulya; Gok, Faysal; Yuksel, Selcuk; Soylu, Alper; Bahat, Elif; Hacihamdioglu, Duygu Ovunc; Candan, Cengiz; Bastug, Funda; AAW-8783-2020
Short-Term Evaluation of Nasal Changes After Maxillary Surgery
(2014) Yilmaz, Alev; Polat-Ozsoy, Omur; Arman-Ozcirpici, Ayca; Uckan, Sina
Objective: To determine the nasal soft-tissue profile changes in skeletal Class III patients who underwent maxillary or bimaxillary orthognathic surgery. Materials and Method: This clinical retrospective study consists of 40 patients (19 male and 21 female) who had undergone orthognathic surgery. All patients received single jaw maxillary (9 patients) or bimaxillary surgery (31 patients). Standardized lateral cephalograms obtained before operation and at least 6 months after the operation were used. Twelve measurements (4 skeletal and 8 soft-tissue measurements) were made. The distributions of the variables were checked by Shapiro-Wilk test. Paired-samples t test was used for parametric data and Wilcoxon sign rank test for nonparametric data, to analyze the differences between pre- and postoperative measurements. Results: After orthognathic surgery, SNA and ANB increased; SNB decreased significantly. A significant reduction in nasofrontal angle, TH-Prn, and nasal tip projection and a significant increase in nasofacial angle were found. In addition, superior movement of the nasal tip was found, and as a result, the nasal hump decreased. The N-Sn/Pr ratio, nasal tip angle, and nasolabial angle did not show any significant changes. Conclusion: It can be concluded that more vertical nasal changes rather than sagittal nasal changes are observed after maxillary surgery.
Turkish Atypical Hemolytic Uremic Syndrome Registry: Eculizumab Treatment İn Ahus Patients
(2018) Baskin, Esra; Canpolat, Nur; Gulleroglu, Kaan; Yilmaz, Alev; Melek, Engin; Yuksel, Selcuk; Gulhan, Bora; Kalyoncu, Mukaddes; Parmaksiz, Gonul; Ozcakar, Birsin; Ozaltin, Fatih; Soylemezoglu, Oguz; https://orcid.org/0000-0003-4361-8508; https://orcid.org/0000-0003-1434-3824; https://orcid.org/0000-0003-2373-1837; B-5785-2018; F-3294-2013; AAM-2935-2021
Turkish Society of Pediatric Nephrology - February 6th Earthquakes Disaster Management
(2023) Bakkaloglu, Sevcan; Yavascan, Onder; Yilmaz, Alev; Gulleroglu, Kaan; Kasap Demir, Belde; Ertan, Pelin; Poyrazoglu, Hakan; 0000-0003-1434-3824; F-3294-2013