Browsing by Author "Yildiz, Ali"

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    Efficacy of Silodosin in the Treatment of Distal Ureteral Stones 4 to 10 Mm in Diameter
    (2015) Yuksel, Mustafa; Yilmaz, Serdar; Tokgoz, Husnu; Yalcinkaya, Soner; Bas, Serkan; Ipekci, Tumay; Yildiz, Ali; Ates, Nihat; Savas, Murat; 0000-0002-3068-4699; 0000-0002-2755-0526; 0000-0003-0293-9989; 26770537; AAD-5570-2019; AAB-2986-2020; GWC-8116-2022
    Purpose: Few studies have investigated the efficacy of silodosin, a recently introduced selective alpha 1-A adrenoceptor antagonist, in medical expulsive therapy (MET) for ureteral calculi. The results of these studies, which all evaluated the efficacy of 8 mg/day, indicate that silodosin is a potential treatment for ureteral calculi. This study investigated the efficacy of 4 mg/day of silodosin for MET of distal ureteral stones 4 to 10 mm in diameter. Material and Method: After 70 patients had been randomized into 2 groups of 35 patients each, both the control and experimental groups (groups 1 and 2, respectively) were advised to take 75 mg/day of diclofenacsodiumas needed for pain relief but only the experimental group to take 4 mg/day of silodosin. After 21 days, the groups were compared regarding the stone expulsion rate and duration, number of renalcolicepisodes, and analgesicdosage. Results: The median expulsion rates were 71.4% and 91.4% in groups 1 and 2, respectively, and the difference between them was significant (P= 0.031). The median expulsion durations were 12.91 +/- 6.14 and 8.03 +/- 4.99 days, respectively, and the difference between them was significant (P< 0.001). No significant differences were found regarding the median number of renal colic episodes or median analgesic dosage. While no patients in group 1 experienced side effects, 5 patients (14%) in group 2 experienced retrograde ejaculation. Conclusion: These results indicate that 4 mg/day of silodos in facilitates the expulsion of distal ureteral stones 4 to 10 mm in diameter but does not significantly reduce the number of renal colic episodes or analgesic dosage.
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    An Extremely Rare Kidney Tumor: Primary Intraparenchymal Squamous Cell Carcinoma
    (2017) Ipekci, Tumay; Yuksel, Mustafa; Yildiz, Ali; Inal, Gulsah; Ipekci, Oncel; 0000-0002-2755-0526; AAB-2986-2020
    Primary squamous cell carcinoma of the renal parenchyma is a rare entity and only 4 cases have been reported in the literature. A 73-year-old female patient presented to our clinic with the complaint of right flank pain. On radiologic evaluation, a 6x5x4 cm hypodense mass showing heterogeneous contrast enhancement was observed in the upper pole of the right kidney. An uneventful laparoscopic radical nephrectomy was performed. Final pathologic diagnosis was squamous cell carcinoma. No pathological involvement was observed on postoperative positron emission tomography/ computed tomography. Our patient is still alive and she has not received any adjuvant treatment.