Browsing by Author "Ucar, Yildiz"

Now showing 1 - 5 of 5

Association between Red Blood Cell Distribution Width and Acute Pancreatitis
(2014) Karabulut, Keziban Ucar; Narci, Huseyin; Ucar, Yildiz; Uyar, Mehmet; 25428195
Background: We aimed to determine whether there are any alterations in red blood cell width in patients diagnosed with acute pancreatitis. Material/Methods: This was a retrospective study of records of patients treated in emergency units and diagnosed with acute pancreatitis between January 2011 and April 2013. Records were investigated regarding patient age, sex, and causes of acute pancreatitis. Red blood cell width and amylase values obtained from the patients during diagnosis and after a full recovery from acute pancreatitis were added to the records. Results: Recorded red blood cell width and amylase values of 104 patients diagnosed with acute pancreatitis were statistically compared according to the time of sample collection. Samples were collected in the post-diagnostic period and after full recovery. Values of red blood cell width and amylase were found to be significantly higher in samples collected during hospital admission in comparison to those obtained from patients after fully recovering from acute pancreatitis (p<0.05). Conclusions: An increase in red blood cell width value is a marker of acute pancreatitis; therefore, we suggest that red blood cell width can be used as a tool for the early diagnosis and assessment of disease progression.
The change of neutrophils/lymphocytes ratio in migraine attacks: A case-controlled study
(2016) Karabalulut, Keziban Ucar; Egercioglu, Tomris Ugur; Uyar, Mehmet; Ucar, Yildiz; 0000-0001-9188-0266; 27551404; AAJ-5618-2021
Objective: As commonly seen symptoms, headaches are among the most frequently encountered health challenges in emergency rooms by healthcare professionals. Among one of the most commonly seen and primary headaches is migraine. Migraines are mostly accompanied by functional deficits. Aims: To observe the changes of neutrophil/lymphocyte ratio occurring during migraine attacks. Method: This is a retrospective study where hospital records of patients previously diagnosed with migraine and admitted to the emergency with the complaints of attacks between May 2014 and January 2015 were investigated. All patients in the study were evaluated as to age, gender and complete blood count. Additionally, a healthy control group was formed with individuals with no disorders. By also evaluating the same features in the controls, the values found in the patients and controls alike were compared. Results: The values of white blood cell, lymphocyte, neutrophil, hemoglobin, thrombocyte and neutrophil/lymphocyte ratio determined in the patient group (n = 92) were statistically compared with those of the controls (n = 67). Neutrophil/lymphocyte ratio during the attacks was found higher in the patients, compared to the controls. Conclusion: Neutrophil/lymphocyte ratio is a sign of inflammation, and we consider that this ratio will also increase during migraine attacks, as with other inflammatory and acute processes. (C) 2016 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
Correlation of Histological Diagnosis and Laboratory Findings in Distinguishing Acute Appendicitis and Lymphoid Hyperplasia
(2022) Karabulut, Keziban Ucar; Erinanc, Hilal; Yonar, Aynur; Kisinma, Alpaslan; Ucar, Yildiz; 0000-0003-1681-9398; 0000-0001-9188-0266; 36452309; S-3177-2018; AAJ-5618-2021
Purpose: Acute appendicitis (AA) is one of the most frequent causes of abdominal surgery encountered in emergency rooms. However, reactive lymphoid hyperplasia (RLH) is one of the appendicular pathologies often misdiagnosed. It is quite challenging to distinguish between AA and RLH in terms of planning treatment in an emergency. Therefore, this retrospective study aimed to compare the histological and laboratory findings of AA and RLH. Methods: The retrospective data included in the study were obtained from patients diagnosed with AA. Complete blood count (CBC) and C-reactive protein (CRP) levels of patients with AA and RLH were compared before the surgery based on the histological diagnosis of the patients. Results: A total of 187 patients who previously underwent appendectomy were included in the study. Histopathological examination revealed that 152 patients (81.3%) were diagnosed with AA, and 35 (18.7%) with RLH. While white blood cell count (P < 0.001), neutrophil (P < 0.001), and neutrophil/lymphocyte ratio (P < 0.001) were found to be significantly higher in those with AA; lymphocyte (P = 0.003) and eosinophil counts (P = 0.033) were detected to be significantly higher in those with RLH. CRP level was also significantly higher in those with AA (P = 0.002) Conclusion: We consider that CBC and CRP levels may be predictive in distinguishing between AA and RLH. We consider that these parameters may be valuable in making a distinction between patients before surgery.
The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department
(2016) Karabulut, Keziban Ucar; Gul, Mehmet; Ucar, Yildiz; Erdem, Sami
Purpose: There are difficulties observed in the diagnosis of acute pancreatitis in emergency departments due to its different clinical properties and the insufficiencies in the methods of diagnosis. Since there is no specific biochemical indicator, the diagnosis is made usually late or with difficulty. Neopterine is an enzyme secreted from the macrophages and is an indicator of cellular immunity activation. The aim of this study was to determine the role of neopterine in the early diagnosis of acute pancreatitis. Material and Methods: 39 patients, who had been hospitalized with the complaints of abdominal pain and diagnosed as acute pancreatitis via laboratory and screening methods, and 30 healthy controls were included in the study. Amylase, lipase, cholesterol and neopterine were measured in the patients' samples. The diagnoses were confirmed with abdominal ultrasound and computed tomography. Results: The neopterine values in patients with acute pancreatitis were significantly higher than those of the control group. Conclusion: Neopterine is an indicator which is elevated in certain inflammatory and autoimmune situations. We believe that it is important in the early diagnosis of acute pancreatitis. Further experimental and clinical studies should be conducted on the subject.
The Significance of Mean Platelet Volume in Acute Pancreatitis
(2016) Karabulut, Keziban Ucar; Ozden, Hale Turan; Ucar, Yildiz
Aim: Acute pancreatitis is a high-mortality disease carrying significant risk of complications and characterized by intra-acinar cell activation of digestive enzymes, followed by a subsequent response via the release of proin-flammatory cytokines. Here, we aimed to investigate the development of mean platelet volume in patients diagnosed with acute pancreatitis. Material and Method: The study was performed in patients admitted to the emergency room with the complaint of abdominal pain and diagnosed with acute pancreatitis. A total of 116 patients were included in the study. Mean platelet volume, leucocytes or white blood cells and lipase values were investigated and compared after all patients had been diagnosed with acute pancreatitis and regained good health. Also, the values of mean platelet volume, white blood cells and lipase were recorded twice for these patients. Results: After diagnosis and complete treatment, the mean platelet volume, white blood cells and the lipase values of 116 acute pancreatitis patients were statistically compared it was found that the values on admission were higher than after the treatment. Discussion: Mean platelet volume is an indicator that increases in acute pancreatitis so, we consider that mean platelet volume may be beneficial in the diagnosis and in monitoring the course of acute pancreatitis.