Browsing by Author "Turker, Perim Fatma"

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The Correlation Of Uric Acid Levels With Biochemical Parameters And Dietary Factors In Individuals With Asymptomatic Hyperuricemia And Gouty Arthritis
(2022) Turker, Perim Fatma; Hoca, Mustafa; Ozduran, Gulsen; Ok, Mehtap Akcil; Celebi, Merve Demir; 35300582
Diet may play an important role in the development of asymptomatic hyperuricemia (ASH) and gouty arthritis (GOUT). However, the association between dietary factors and hyperuricemia remains unclear. Serum uric acid levels are affected by dietary factors. This study aimed to evaluate the correlation of uric acid levels with biochemical parameters and dietary factors in individuals with ASH and GOUT. This study was conducted in 145 individuals with ASH and GOUT. General characteristics of individuals were collected via face-to-face interviews. Food frequency questionnaire was used to obtain energy, macro- and micronutrients intakes. Biochemical parameters were obtained from patient files. The incidence of gout was higher in men comparing to women. Individuals in the GOUT group consumed more alcohol and higher serum levels of vitamin B-12, C-reactive protein (CRP), triglyceride, and uric acid. Individuals in the GOUT group had higher intakes of energy, protein, carbohydrate, fat, fructose, vitamin C, and vitamin B-12. Triglyceride, uric acid, CRP, vitamin B-12, and homeostatic model assessment of insulin resistance were found to be affected by high uric acid levels. Dietary factors can pose a risk for health problems in addition to GOUT and ASH, such as cardiovascular disease, diabetes, and obesity.
The Effects of Glucose and Fructose on Body Weight and Some Biochemical Parameters in Rats
(2018) Koseler, Esra; Kiziltan, Gul; Turker, Perim Fatma; Saka, Mendane; Ok, Mehtap Akcil; Bacanli, Didem; Aydos, Tolga Resat; Bayraktar, Nilufer; Ozdemir, Handan; 0000-0002-4254-3711; 0000-0002-1832-9336; 0000-0002-7886-3688; AAZ-8170-2020; AAJ-7279-2020; Y-8758-2018
Objective: Dietary fructose from added sugar as high fructose corn syrup may causes major risks in obesity, hyperlipidemia, cardiovascular diseases, hyperuricemia and fatty liver. The aim of this study was to investigate and compare the effects of high fructose and high glucose intake on body weight and some biochemical parameters in rats. Subject and methods: The study was conducted on adult, 32 Wistar albino male rats (300-350 g weeks) which fed with standard laboratory chow. In each group, 8 rats was selected randomly and which was be composed four groups. The rats in each group, in addition to standard meal, different amount of glucose and fructose containing solutions (10% and 30% glucose-fed group, 10% and 30% fructose-fed group) was given by oral gavage for 6 weeks. At baseline and after 6 weeks total cholesterol, VLDL-cholesterol, triglycerides, uric acid, AST and ALT as biochemical parameters and liver histopathological examination of rats were determined. Body weight of the rats was evaluated every week. Results: The 30% fructose group caused higher AST levels according to 10% glucose group, 30% glucose group and 10% fructose group. At the end of 6 weeks, the mean body weight in the fructose-fed groups was higher than the glucose-fed groups (p>0.05). No statistically significant difference between rat groups' portal inflammation rates were found and the moderate and severe ballooning were observed in 30% fructose rats (p<0.05). Conclusions: As a result, dietary fructose from added sugar as high fructose corn syrup may causes major metabolic disorders.
Effects of Nutrition Education Given to Persons with Multiple Sclerosis and Their Families on Diet Quality and Anthropometric and Biochemical Measurements
(2022) Uzdil, Zeynep; Turker, Perim Fatma; Terzi, Murat
Objective In this study, it was aimed to investigate the effects of nutrition education given to persons with multiple sclerosis and their families on anthropometric and biochemical measurements and diet quality. Methods Data from 51 persons with multiple sclerosis were analysed in this intervention study. The study was conducted with 3 groups. The education group consisted of only persons with multiple sclerosis, the family education group consisted of persons with multiple sclerosis and a family member living with them, and the control group consisted of persons with multiple sclerosis who had not received an education. Anthropometric and biochemical measurements and dietary quality assessments were made before (T1) and immediately after education (T2) and also 3 months after education (follow-up, T3). Results The distribution of family education group diet quality scores showed a significant increase from "poor" to "needs improvement" at T3 compared to T1. The upper middle arm circumference measurements of the female control group were decreased at T2 and T3 [from 29.0 (23-34) cm to 28.0 (22-31) cm and to 27.5 (22-31) cm]. Women in family education group, levels of serum haemoglobin and haematocrit were higher than in control group at T2 and T3. Also, men in family education group, levels of alanine aminotransferase were lower than those in education group at follow up. Levels of total cholesterol and low-density lipoprotein cholesterol in education group were higher than those control group at T1, T2, and T3. Conclusion This study indicates that nutrition education affects some biochemical and anthropometric measurements in persons with multiple sclerosis. Diet quality improved when receiving education together with families.
Effects of Nutritional Knowledge of Informal Caregivers on Depression and Metabolic Outcomes of Hemodialysis Patients
(2021) Kiziltan, Gul; Turker, Perim Fatma; Beyaz, Esra Koseler; Saka, Mendane; Sayin, Cihat Burak; 0000-0001-8287-6572; 34459351; J-3707-2015
Chronic renal failure (CRF) makes significant changes in the life of patients and their families. A good family support has a positive effect on successful patients' adaptation to the treatment and compliance with dietary regimen. This study aimed to examine the effects of nutritional knowledge of informal caregivers on depression and metabolic outcomes of hemodialysis patients. This was a cross-sectional study conducted at Baskent University Hemodialysis Center with 116 hemodialysis patients and their informal caregivers. Findings revealed that the caregivers who were the couple of the patients had the highest nutritional knowledge level than the other caregivers (p < .05). The postgraduate caregivers were more likely to have high nutritional knowledge level than the others (p < .05). The inflammation marker of the patients was significantly lower in the group of caregivers with higher level (T3 group) of nutritional knowledge than the others (p < .05). The mean CES-D scores were also more likely to be low in T3 group than in the others (p < .05). These findings highlight that the nutritional knowledge of caregivers of hemodialysis patients may have an additional benefit on patients' nutritional management and metabolic outcomes.
Effects of reproductive and sociodemographic factors on obesity in Turkish women: a pilot study
(2019) Bayram, Sinem; Koseler, Esra; Kiziltan, Gul; Ok, Mebtap Akcil; Yesil, Esen; Kose, Beril; Ozdemir, Merve; Muftuoglu, Selen; Saka, Mendane; Aksoydan, Emine; Tayfur, Muhittin; Turker, Perim Fatma; Ercan, Aydan; 0000-0003-1569-7747; 0000-0002-4254-3711; AAF-4491-2021; AAG-6763-2020
Background and aim: Obesity has become a global epidemic. The current research aimed to determine sociodemographic and reproductive predictors of obesity among Turkish women. Materials and methods: Eligible subjects (n:833) were 40-64 years-old women living in Turkey. A questionnaire consisted of questions about sociodemographic and reproductive factors and the International Physical Activity Questionnaire were applied to participants by face to face interviews. Multivariate logistic regression examined the risk of being obese with a range of sociodemographic and reproductive factors. All analyses were performed with SPSS software (version 17.0; SPSS, Chicago, Ill., USA). Results: The mean BMI of women aged 51-64 years was 30.59 +/- 6.35 kg/m(2). After adjustments for all other variables, increased obesity risk remained significant in women who had two children, housewifes, minimum active ones, ex smokers and had less than high school education. For multiple regression analysis sociodemographic factors from the bivariate analyses were entered, controlling for menarch age, menopausal age, hormone RT, parity, number of stillbirth, abortion. There was significant association between family income, occupation, education and BMI. Conclusion. In summary these findings showed comparable patterns of association of sociodemographic and reproductive factors with obesity in Turkey. Specific healthy lifestyle counseling is important for decreasing obesity in childbearing age women.
Fetal Programming: Could Intrauterin Life Affect Health Status in Adulthood?
(2021) Ozturk, Hande Nur Onur; Turker, Perim Fatma; 34670066
Intrauterine life is one of the most important periods of life. As the development of the fetus continues, the mechanisms that affect adult health also begin to mature. With the hypothesis denoted "fetal programming," it is thought that the presence of endocrinological disorders, toxins, infectious agents, the nutritional status of a mother, and nutrients related to placental functionality all have an effect on future life. Therefore, the fetus must adapt to the environment for survival. These adaptations may be involved the redistribution of metabolic, hormonal, or cardiac outputs in an effort to protect the brain, which is one of the important organs, as well as the slowing of growth to meet nutritional requirements. Unlike lifestyle changes or treatments received in adult life, the early developmental period tends to have a lasting effect on the structure and functionality of the body. In this review, fetal programming and the effects of fetal programming are discussed.
Nutritional Support in Older Patients with Esophageal Cancer Undergoing Chemoradiotherapy
(2022) Dogan Akagunduz, Digdem; Turker, Perim Fatma; 35786221
Esophageal cancer (EC) is the eighth most prevalent malignancy and the sixth leading cause of cancer-related death worldwide. The proportion of older adults with EC has increased dramatically in recent decades due to increased life expectancy. Older patients with EC are at a highest risk of malnutrition and this predicts early death. In older patients with EC, dysphagia is a common symptom; additionally, comorbidities, polypharmacy, and physiological changes of aging such as decreased muscle mass and geriatric issues including altered cognition, mobility, and mood contribute to malnutrition. Chemoradiotherapy (CRT) is the primary treatment for unresectable locally advanced EC patients, as it successfully reduces local recurrence and distant metastases while also extending survival. In older patients with EC, nutrition is an interventional condition, unlike many other geriatric risk factors. Optimizing nutritional support may reduce treatment toxicity and facilitate the completion of definitive or neoadjuvant CRT. The relevance of nutritional status and food intake is becoming more widely acknowledged, and it now encompasses the entire spectrum of EC treatment in older patients, from diagnosis to perioperative care to long-term care. This review aims to discuss the current research on nutritional support in older patients with esophageal cancer undergoing CRT.
The Relationship Between Body Image and Anthropometric Measurements Among Adolescent Girls During Menstrual and Non-menstrualtime Periods: A Cross-Sectional Study
(2022) Turker, Perim Fatma; Caliskan, Hilal; Bayram, Sinem
Introduction: In recent studies, it has been suggested that anxiety about body image increases during menstruation in adolescents and may affect nutritional status. This study aimed to evaluate the relationship between adolescents' body images, body perceptions and anthropometric measurements during menstrual and non-menstrual time periods.Methods: This cross-sectional study was carried out in a private high school between September November 2021. Participants were adolescent girls aged 14-18. The questionnaire included information about menstruation, anthropometric measurements, and the Body Cathexis Scale (BCS) and Stunkard Figure Rating Scale.Results: The mean age (total=291) was 15.9(1.13) years, body mass index (BMI) was 21.13(3.33) kg/m2, waist circumference was 70.48(8.87) cm and the BCS was 97.39(24.59). The majority of students have normal BMI. However, according to waist circumference 28.5% of the them were obese (>= 90th percentile). Difference between actual BMIs and body image in the menstrual period was significant (p<0.001), the agreement with each other was slight (K=0.172). There was a significant difference (p<0.001) between actual BMIs and body image in the non-menstrual period and the agreement with each other was moderate (K=0.474). During non-menstrual periods, 79.7% of students with normal BMI perceived their body images as normal, and 70.5% of overweight students perceived as overweight.Conclusions: Since the menstruation is a period in which body image is perceived differently than it is, special consideration of adolescent girls in terms for eating disorders should be encouraged.
The relationship between quality of life and anthropometric measurements in premenopausal and postmenopausal among turkish women
(2019) Kose, Beril; Yesil, Esen; Turker, Perim Fatma; Ok, Mehtap Akcil; Bayram, Sinem; Beyaz, Esra Koseler; Ozdemir, Merve; Muftuoglu, Selen; Tayfur, Muhittin; Aksoydan, Emine; Ercan, Aydan; Saka, Mendane; Kiziltan, Gul; 0000-0003-1569-7747; AAG-6763-2020
The aim of this work was to investigate whether there is a relationship between anthropometric measurements and quality of life scores during pre and postmenopouse period. A descriptive study was carried out on 1276 women (40-64 years). Demographic features, socioeconomic attributes and anthropometric measurements were considered using a validated instrument the Turkish version of the EUROHIS (WHOQOL-8.Tr) was performed. Significant body mass index (BMI), height, waist circumference, hip circumference, waist/ height ratio differences were determined by comparing pre and postmenopausal women (p <0.05). Significantly lower quality of life scores were observed in premenopausal women (p<0.05). BMI was determined as significant predictor for quality of life for each group. The number of pregnancy, number of live birth, number of stillbirth and waist/height ratio did not show significant association with quality of life. The age of first pregnancy was stated as significant predictor for quality of life just for premenopausal women. In our study, quality of life increased as the BMI decreased in pre and postmenopausal women. Significantly lower WHO-8 EUROHIS scores were observed in premenopausal women. The age of first pregnancy affected the life quality in positive way in just premenopausal women. As the age of first pregnancy increased, quality of life score increased in premenopausal women.