Browsing by Author "Turan Ozden, Hale"

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    Factors Affecting Inadequate Empirical Antimicrobial Therapy and the Clinical Course of Upper Urinary Tract Infections in Elderly Patients: A Multicenter Study
    (2020) Turan Ozden, Hale
    Introduction: In this study, we aimed to determine the risk factors associated with inadequate empirical antibiotherapy (IEAT) and hospital-related mortality in elderly patients being treated for upper urinary tract infections (UTI). Materials and Methods: This study included individuals aged 65 years and over who were hospitalized after being diagnosed of community-acquired UTI or community-onset healthcare-associated UTI and followed-up in clinics and/or intensive care units (ICU) of 33 hospitals between March and September 2017. Results: A total of 525 patients (48% males; mean age: 76.46 +/- 7.93 years) were included in the study. Overall, 68.2% of the patients were hospitalized through the emergency department and 73.9% of patients were followed-up for pyelonephritis. Gram-negative, Gram-positive, and Gram-negative and positive mix growths were determined in 88%, 9.3%, and 2.7% of urine cultures, respectively. Fifty-six (10.7%) of the patients died. In multivariate analysis, the presence of chronic obstructive pulmonary disease [Odds ratio (OR): 2.278], age 85 years and over (OR: 2.816), admission to the ICU (OR: 14.831), and IEAT (OR: 2.364) were independent factors that significantly affected mortality. The presence of a urinary catheter, being followed-up in the ICU, benign prostate hypertrophy, use of antibiotics other than piperacillin-tazobactam and carbapenem were determined as independent factors that significantly affected IEAT (p<0.05). Conclusion: In our study, we found a direct correlation between IEAT and mortality. Therefore, knowing the most frequent microorganisms and antibiotic susceptibility profiles observed in the UTI of elderly patients may help to decrease the mortality and morbidity associated with these infections.
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    The Ways to How Patients with Chronic Hepatitis C Find Out Their Disease and Risk Factors
    (2019) Turan Ozden, Hale
    Introduction: Transmission routes and seroprevalence of hepatitis C virus (HCV) may vary between countries and geographic regions. In this study, we planned to investigate patients with chronic hepatitis C admitted to our hospital in order to identify associated risk factors of HCV transmission in our region. Materials and Methods: Eighty-two patients who were admitted to the Infectious Diseases and Clinical Microbiology Outpatient Clink of our hospital between January 2011-December 2014 and who were diagnosed with chronic hepatitis C and/or liver cirrhosis were included into the study. Results: Forty-six (56.1%) of the patients were female and 36 (43.9%) were male patients. Mean age was 60.8 +/- 10.0 (26-81) year. Most common risk factors were surgical intervention (58.5%) and dental treatment (31.7%). Vast majority of the patients found out about their illnesses during routine examinations (81.7%). Conclusion: Early detection of the HCV infection is important in the follow-up and treatment of the disease. This study also emphasized the importance of routine screening in the detection of anti-HCV positivity.