Browsing by Author "Tunckiran, Ahmet"

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Continuous positive airway pressure therapy is associated with improvement in overactive bladder symptoms in women with obstructive sleep apnea syndrome
(2016) Ipekci, Tumay; Cetintas, Gulgun; Celik, Orcun; Ekin, Rahmi Gokhan; Sarac, Sema; Tunckiran, Ahmet; Ilbey, Yusuf Ozlem; 27123331
Introduction To evaluate the impact of continuous positive airway pressure (CPAP) therapy on overactive bladder (OAB) symptoms in women with obstructive sleep apnea syndrome (OSAS). Material and methods One-hundred and fifty women underwent an overnight polysomnography study between May 2014 and September 2014. Their voiding symptoms were evaluated using the OAB symptom score (OABSS) and International Consultation on Incontinence Questionnaire Short-Form at OSAS diagnosis and approximately 3-months after CPAP therapy. OSAS severity was assessed according to the apnea-hypopnea-index. Results We evaluated 140 women and 111 of them (79.3%) reported symptoms consistent with OAB. There were no statistically significant differences between OSAS severity with a prevalence of OAB (p = 0.92). The prevalence of urinary incontinence (UI) was 35.7% (n = 50) and 39.6% (n = 44) in all patients and patients with OAB, respectively. There were no statistically significant differences between UI with OAB (p = 0.58). Baseline OABSS is comparable between OSAS severity (p = 0.143). After 3-months CPAP therapy, OABSS and ICIQ-SF sum scores were significantly decreased in patients with severe and moderate OSAS (p < 0.01), however, change of OABSS sum score was insignificant in patients with mild OSAS (p = 0.44). Conclusions CPAP therapy improves the OAB, OABSS and ICIQ-SF scores in women with severe and moderate OSAS. OSAS-induced OAB may be alleviated following CPAP therapy.
The Impact of Hypoxemia on Serum Total and Free Prostate-Specific Antigen Levels in Patients with Chronic Obstructive Pulmonary Disease
(2015) Ozge, Cengiz; Bozlu, Murat; Ozgur, Eylem Sercan; Tek, Mesut; Tunckiran, Ahmet; Muslu, Necati; Ilvan, Ahmet; 0000-0001-7303-7064; 25837435; V-6440-2019
Prostate-specific antigen (PSA) is the most important biochemical marker in the diagnosis and follow-up of patients with prostate cancer. In recent years, a relationship between PSA levels and hypoxic conditions has been described. However, no study has investigated the PSA levels in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the impact of hypoxemia on serum total (tPSA) and free PSA (fPSA) levels in patients with COPD. Between January 2010 and January 2014, 95 male patients who hospitalized for acute exacerbations of COPD and 80 control subjects were enrolled in the study. Serum tPSA and fPSA levels and f/tPSA ratios were determined in all patients on the first day of hospitalization (exacerbation) and 7 days after the treatment (stable state). Statistical analysis included paired t test and Mann-Whitney U test. No statistically significant differences were found between COPD and control groups with regard to the baseline characteristics, except for smoking status. The levels of serum tPSA and fPSA during exacerbation of COPD were significantly higher than the levels of the stable period (p < 0.01), whereas f/tPSA ratio did not change (p > 0.05). Hypoxemia during acute exacerbation of COPD can cause a rise in serum tPSA and fPSA levels, but f/tPSA ratio is not affected. Acute exacerbation of COPD may be added to list of the events in which PSA measurements must be interpreted with caution.
Is Preoperative Neutrophil Lymphocyte Ratio a Reliable Prognostic Parameter for Localized Prostate Cancer?
(2017) Ipekci, Tumay; Tunckiran, Ahmet; Yuksel, Mustafa; Ucar, Murat; Kozacioglu, Zafer; Akman, Ramazan Yavuz; 0000-0001-7303-7064; 0000-0002-2755-0526; V-6440-2019; AAB-2986-2020; AAD-3028-2020
Objective: In spite of all efforts, prostate cancer is still the 2nd highest cause of cancer-related deaths in men. For this reason new developments are needed in diagnosis, treatment and follow-up of prostate cancer. Neutrophil/lymphocyte (N/L) ratio is a cheap and effective parameter used for research into many solid tumors; but there are not enough studies on the reliability of this parameter in prostate cancer. In this study we researched the efficacy of N/L ratio in localized prostate cancer. Materials and Methods: Between March 9, 2012 and April 23, 2017, the data of 140 patients who underwent radical prostatectomy with localized prostate cancer were screened retrospectively. The patients' ages, preoperative prostate specific antigen (PSA) and N/L ratio, pathologic stage, pathologic Gleason score, tumor volume, lymph node involvement, surgical margin positivity and presence or absence of 3rd month biochemical recurrence were noted. The correlations between N/L ratio with age, PSA, pathologic parameters, surgical margin positivity and biochemical recurrence were investigated. Results: The mean age of patients was 63.0 +/- 5.9 years, mean PSA value was 10.8 +/- 8.5 ng/mL and mean N/L ratio was 2.5 +/- 1.9. There was no correlation found between N/L ratio and PSA, pathologic stage, Gleason score, lymph node involvement, tumor volume, surgical margin positivity and biochemical recurrence (p>0.05). Conclusion: In our study investigating 140 patients with localized prostate cancer, we did not identify any correlation between N/L ratio and PSA, surgical stage and Gleason score, surgical margin positivity, and 3rd month biochemical recurrence. When the literature is investigated, it appears that N/L ratio is effective for metastatic prostate cancer. To provide a more accurate judgment of the role of N/L ratio in localized prostate cancer, there is a need for new studies with broader patient series.
Publication Rates and Citation Analysis of Oral and Poster Presentations at the First Congress of the Society of Urological Surgery in Turkiye
(2018) Ipekci, Tumay; Yuksel, Mustafa; Karamık, Kaan; Anil, Hakan; Tunckiran, Ahmet; 0000-0002-2755-0526; 0000-0001-7303-7064; AAB-2986-2020; V-6440-2019
Objective: Publications of congress presentations (oral/poster) contribute to the literature by creating new information. In this study, we examined the publication rate of poster and oral presentations at the 1st Congress of the Society of Urological Surgery in Turkiye held in 2012. Materials and Methods: We investigated the congress booklet belonging to the 1st Congress of the Society of Urological Surgery in Turkiye held in 3-7 October 2012. We investigated the publication rates of 176 poster and 103 oral presentations under the headings of uro-oncology, andrology, pediatric urology, endourology, transplantation, continence and other by searching the PubMed and Science Citation Index Expanded (SCI-E) databases. Results: Of the 176 poster and 103 oral presentations, 79 (28.3%) were subsequently published. The publication rate in journals included in the SCI-E was 24.3%. While 33% of oral presentations were published, 25.5% of poster presentations became publications and this difference was not found to be statistically significant (p= 0.48). The mean duration from presentation to publication was 21.1 months. Conclusion: The publication rate of presentations at the 1st Congress of the Society of Urological Surgery in Turkiye was higher than in most national congresses in different disciplines, but lower than many international congresses in the field of urology. Future studies investigating congress data from several consecutive years will provide clearer results.
Publication rates of dissertations written in medical faculties of Turkey in the field of urology between the years 2008, and 2011, and citation analysis: A cross-sectional study
(2018) Ipekci, Tumay; Tunckiran, Ahmet; Yuksel, Mustafa; 29799403; V-6440-2019
Objective: In our country, preparing dissertation is essential for the research assistants in order to complete their expertise in medicine. It is aimed to produce hypothesis for researchers via writing their dissertations, to collect data for the hypothesis established, to make the analysis and interpretation of these data, and to gain the ability for the comparison of the findings obtained with the literature. In this study, we want to investigate the publication rates and citations of urology dissertations that are written at the university hospitals in our country between 2008 and 2011. Material and methods: Urology dissertations that are written at the university hospitals between 2008 and 2011 were reviewed by entering the website of Board of Higher Education Dissertation between 23-27 March 2017 and 229 dissertations were reported. The publication rates of these dissertations were analysed. Results: Hundred and fourteen of 229 dissertations (49.7%) analysed were published. Of these publications, 75 (32.7%) in Science Citation Index Expanded, 24 (10.4%) in international, 15 (6.5%) are published in national indexed peer-reviewed journals. While the publication rate of 81 dissertations written in universities located in 3 metropolitan cities (Istanbul, Ankara, and Izmir) of Turkey was 50.6%, the publication rate of 148 dissertations written in remaining universities was 49.3%; and no statistically significant difference was found between the two groups (p=0.96). Conclusion: Preparing dissertation is a challenging process that requires considerable effort and time. At the end of this process, it is necessary to publish the dissertation in order to have it reach more people and to contribute to the literature. Even though publication rate of dissertations written in urology at university hospitals in Turkey was at acceptable level, there have still been problems required to solve.
Top cited articles in urology from Turkey
(2017) Ipekci, Tumay; Yuksel, Mustafa; Tunckiran, Ahmet; 0000-0002-2755-0526; 28270953; AAB-2986-2020
Objective: Citation is the name given for a scientific publication in order to be used as a reference by another publication. In this study, we reviewed the most frequently cited publications in urology from Turkey. Material and methods: On March 7-14, 2016, 51 studies with highest number of citations from Turkey are determined from Science Citation Index Expanded database index and the journals in which studies are published, the authors of the publications, their cities and departments, study types, publication date of the studies and the number of citations are recorded. Results: The most frequently encountered subjects in the publications that are mostly cited from Turkey are urolithiasis (23.5%), infertility (15.6%), benign prostatic hyperplasia (11.7%), sexual dysfunction ( 11.7%) and bladder carcinoma/urothelial carcinoma (9.8%). Distribution of 51 publications is as follows: 18 case series, 11 randomized study, 7 non-randomized study, 6 study, 3 review, 3 cross-sectional studies and 3 survey studies. Of all the studies, 68.6% are from Ankara, Istanbul and Izmir and 72.5% of them have originated from the university hospitals. Conclusion: It is important to show the most cited Turkish publications in order to show the contribution in the world literature regarding to urology. The most cited publications in Turkey belong to urolithiasis and andrology areas. When the citation analysis publications in urology and different areas both in Turkey and in the world, it is observed that the number of our qualified publications is at acceptable levels.