Browsing by Author "Tugcu, Ali Ulas"

Now showing 1 - 11 of 11

Acupressure at BL60 and K3 Points Before Heel Lancing in Preterm Infants
(2015) Abbasoglu, Aslihan; Cabioglu, Mehmet Tugrul; Tugcu, Ali Ulas; Ince, Deniz Anuk; Tekindal, Mustafa Agah; Ecevit, Ayse; Tarcan, Aylin; 0000-0002-2232-8117; 0000-0002-4060-7048; 0000-0002-4369-2110; 26242287; ABI-2113-2020; AAJ-4616-2021; U-9270-2018; I-6746-2016
Context: Acupressure is an ancient Chinese healing art. In this pain-relieving method, the fingers are used to press key acupuncture points on the skin surface that stimulates the body's regulatory processes. Objective: The aim of this study was to investigate the effect of acupressure at Kun Lun (UB60) and Taixi (K3) points for pain management in preterrn infants prior to heel lancing for blood collection. Design: This was a prospective, randomized controlled study. Setting: The study setting was the neonatal intensive care unit at Baskent University Hospital in Turkey. Patients: A total of 32 preterm infants between 28 and 36 weeks' gestational age were randomly assigned to one of two groups: an acupressure group (n = 16) or a control group (n = 16). Intervention: In the acupressure group, immediately before the heel prick, acupressure was applied for three minutes at UB60 and K3 points. Main Outcome Measures: A behavioral pain score was determined using the Premature Infant Pain Profile (PIPP) scale. Results: There were no significant differences between the groups with respect to gestational age, birth weight, sex, mode of delivery, age at time of procedure, weight at time of procedure, or PIPP score. Mean duration of procedure and mean duration of crying were both shorter in the acupressure group (both P = .001). Conclusions: Applying acupressure at the BL60 and K3 points before heel lancing was associated with shorter procedural time and shorter duration of crying in preterm infants.
Complete Fetal Atrioventricular Block Associated with Maternal Autoinflammatory Diseases: Case Report and Literature Review
(2020) Tugcu, Ali Ulas; Ince, Deniz Anuk; Esin, Sertac; Turan, Ozden; Erdogan, Ilkay; Ecevit, Ayse; 0000-0002-2232-8117; 0000-0002-7707-1881; 0000-0001-9577-4946; 0000-0002-4369-2110; 31903011; AAJ-4616-2021; AAJ-2333-2021; AAJ-2305-2021; AAI-8810-2021; I-6746-2016
Evaluation of Moro reflex with an objective method in late preterm and term infants
(2019) Ince, Deniz Anuk; Ecevit, Ayse; Yildiz, Metin; Tugcu, Ali Ulas; Ceran, Burak; Tekindal, Mustafa Agah; Turan, Ozden; Tarcan, Aylin; 0000-0002-4369-2110; 0000-0002-2554-6953; 30660088; I-6746-2016
Evaluation of peripheral perfusion in term newborns before and after Yintang (EX-HN 3) massage
(2015) Tugcu, Ali Ulas; Cabioglu, Tugrul; Abbasoglu, Aslihan; Ecevit, Ayse; Ince, Deniz Anuk; Tarcan, Aylin; 26742308
OBJECTIVE: To identify how acupressure on the acupoint Yintang (EX-HN 3) impacts oxygen saturation, pulse rate, and peripheral perfusion in term-born infants without underlying disease. METHODS: Infants born between weeks 37 and 42 of gestation were included in this study. The polyclinic's neonatology room was noise-controlled and made half-dark to prevent the perfusion index from being confounded. A pulse oximeter was linked to the baby's left lower extremity. Acupressure was applied on Yintang (EX-HN 3) for 30 s clockwise, held for 30 s, and then acupressure was applied for another 30 s counterclockwise. The baby's SaO(2), pulse rate, and perfusion index were recorded for each minute before and after acupressure. RESULTS: When pre- and post-acupressure pulse rate values were compared, a significant decrease in pulse rate values after acupressure application was observed. When pre- and post-acupressure oxygen saturation values were compared, a significant increase in post-acupressure oxygen saturation was observed. In addition, peripheral perfusion increased significantly after acupressure. CONCLUSION: Acupressure application has been used in traditional medicine for many years. However, it is not yet widely used in modern medicine. This study shows the impact of acupressure on neonatal skin perfusion, oxygen saturation, and pulse rate. (C) 2015 JTCM. All rights reserved.
Experience with Continuous Venovenous Hemodiafiltration in Four Newborns: A Case Series and Review of the Literature
(2015) Tugcu, Ali Ulas; Kantar, Asli; Abbasoglu, Aslihan; Ecevit, Ayse; Tarcan, Aylin; Baskin, Esra; 0000-0002-2232-8117; 0000-0003-4361-8508; 25330394; ABI-2113-2020; AAJ-4616-2021; B-5785-2018
When conventional methods for treating complicated problems such as acute and chronic renal failure or metabolic diseases fail, the therapy of choice is peritoneal dialysis (PD) in neonatal period. However, in cases that involve technical difficulties, such as bulky lesions in the abdomen or complications from previous abdominal surgeries, it is not always possible to place a peritoneal catheter. In such situations, continuous venovenous hemodiafiltration (CVVHDF) can be effective. This case series presents our experience in 2013 with the administration of CVVHDF to four patients in our neonatal intensive care unit who could not undergo PD for various reasons.
Goniometer Measurements of Oral Labial Angle and Evaluation of Oral Motor Reflexes in Preterm Infants: Comparison to Findings in Term Infants
(2015) Ince, Deniz Anuk; Tugcu, Ali Ulas; Ecevit, Ayse; Ciyiltepe, Muzeyyen; Kurt, Abdullah; Abbasoglu, Aslihan; Tekindal, Mustafa Agah; Tarcan, Aylin; 0000-0002-4430-444X; 0000-0002-2232-8117; 0000-0002-4369-2110; 0000-0003-4161-8117; 0000-0002-4060-7048; 25792430; HIU-0129-2022; AAJ-4616-2021; I-6746-2016; Q-1547-2019; U-9270-2018; ABI-2113-2020
To date, no study has evaluated changes in oral labial angle as preterm infants mature. The main purpose of this study was to document goniometer measurements of the labial angle of the mouth in preterm infants, to assess changes with development, to compare to findings in healthy term infants, and also evaluate oral motor reflexes in these groups. Seventy-eight preterm infants and 45 healthy term infants were recruited for the prospective study. Labial angle was assessed via goniometer, and oral motor reflexes and the volume of milk ingested were evaluated. There was significant difference between term and preterm infants' labial angles (P < .01). The distribution of preterm infants' angles were similar to term infants' by 36 to 40 weeks' postmenstrual age. Goniometer measurements of the oral labial angle may reveal oral motor performance in preterm infants and may be relevant for feeding skills assessment in this group of infants.
Hemolytic anemia caused by non-D minor blood incompatibilities in a newborn
(2019) Tugcu, Ali Ulas; Ince, Deniz Anuk; Turan, Ozden; Belen, Burcu; Olcay, Lale; Ecevit, Ayse; 31692740
Hyperbilirubinemia is one of the most widely seen cause of neonatal morbidity. Besides ABO and Rh isoimmunization, minor blood incompatibilities have been also been identified as the other causes of severe newborn jaundice. We report a newborn with indirect hyperbilirubinemia caused by minor blood group incompatibilities (P1, M, N, s and Duffy) whose hemolysis was successfully managed with intravenous immunoglobulin therapy. A thirty-two gestational weeks of preterm male baby became severely icteric on postnatal day 11, with a total bilirubin level of 14.66 mg/dl. Antibody screening tests revealed incompatibility on different minor groups (P1, M, N, s and Duffy (Fya ve Fyb)). On postnatal day thirteen, the level of bilirubin increased to 20.66 mg/dl although baby was under intensive phototherapy. After the administration of intravenous immunoglobulin and red blood cell transfusion, hemoglobin and total bilirubin levels became stabilised. Minor blood incompatibilities should be kept in mind during differential diagnosis of hemolytic anemia of the newborn. They share the same treatment algorithm with the other types hemolytic anemia. New studies revealed that intravenous immunoglobulin treatment in hemolytic anemia have some attractive and glamorous results. It should be seriously taken into consideration for treatment of minor blood incompatibilities.
The Influence of Igm-Enriched Immunoglobulin Therapy on Neonatal Mortality and Hematological Variables in Newborn Infants with Blood Culture-Proven Sepsis
(2014) Abbasoglu, Aslihan; Ecevit, Ayse; Tugcu, Ali Ulas; Yapakci, Ece; Tekindal, Mustafa Agah; Tarcan, Aylin; Ecevit, Zafer; https://orcid.org/0000-0002-4060-7048; 25341598; ABI-2113-2020; U-9270-2018
The aim of this study was to determine the effects of adjuvant immunoglobulin M (IgM)-enriched intravenous immunoglobulin (IVIG) therapy on mortality rate, hematological variables and length of hospital stay in newborn infants with blood culture-proven sepsis. Demographic and clinical features and outcome measures of 63 newborn infants with blood culture-proven sepsis were documented retrospectively from the medical records. The patients were divided into two groups according to their treatment history. The patients in Group 1 received antibiotic therapy only and the patients in Group 2 received both antibiotic and adjuvant IgM-enriched IVIG. The study revealed that mortality rates were 28.1% and 12.9% in Group 1 and Group 2, respectively. The mortality rate was lower in Group 2, but the difference between the two groups was not statistically significant (p=0.21). Coagulase-negative Staphylococcus was the most common type of bacteria isolated from the blood culture in both groups. When changing laboratory results were compared between the two groups, hemoglobin, leukocyte count and C-reactive protein levels were different during the first three days of antibiotic treatment. Our study revealed that if diagnosed at an early stage and treated aggressively with appropriate and effective antibiotics, adjuvant IgM-enriched IVIG treatment has no additional benefits in neonatal sepsis.
Laser Acupuncture Before Heel Lancing for Pain Management in Healthy Term Newborns: A Randomised Controlled Trial
(2015) Abbasoglu, Aslihan; Cabioglu, Mehmet Tugrul; Tugcu, Ali Ulas; Yapakci, Ece; Tekindal, Mustafa Agah; Tarcan, Aylin; 0000-0002-4060-7048; 26438556; AIC-4823-2022; ABI-2113-2020; U-9270-2018
Background Healthy term newborns commonly undergo painful procedures during routine follow-up visits. Non-pharmacological strategies have currently become more important than pharmacological analgesic agents in neonatal pain management. Acupuncture is a new non-pharmacological method for preventing pain in newborns. Objective We aimed to investigate the effect of laser acupuncture (LA) at the Yintang point before heel lancing as a non-pharmacological intervention for procedural pain management in infants. MethodsForty-two term newborns, who were undergoing heel lancing between postnatal days 3 to 8 as part of routine neonatal screening, were randomly assigned to the LA group or the oral sucrose group. In the LA group, 2 min before the heel lancing, 0.3 J of energy was applied to the Yintang point using a Laser PREMIO-30 unit for 30 s. In the sucrose group, each infant received 0.5 mL of 24% sucrose orally via syringe 2 min before the heel lancing. Each baby's behaviour was scored using the Neonatal Infant Pain Scale (NIPS), assessed blinded to group. Results There were no significant differences between the LA and oral sucrose groups with respect to means for gestational week of age at birth, birth weight, actual weight, or Apgar score. Mean procedure time was significantly shorter in the LA group; however, mean crying time was longer and NIPS score was lower compared to the oral sucrose group. Conclusions Our results indicate that 0.3 J of LA at the Yintang point before heel lancing is less effective than oral sucrose for reducing the discomfort of this procedure.
Neonatal Thyrotoxicosis with Severe Supraventricular Tachycardia: Case Report and Review of the Literature
(2015) Abbasoglu, Aslihan; Ecevit, Ayse; Tugcu, Ali Ulas; Erdogan, Ilkay; Kinik, Sibel Tulgar; Tarcan, Aylin; 0000-0002-2232-8117; 0000-0001-6887-3033; 25153577; AAJ-2305-2021; AAJ-4616-2021; ABB-2220-2021; ABI-2113-2020
Neonatal thyrotoxicosis is a rare condition caused by the transplacental passage of thyroid stimulating immunoglobulins from mothers with Graves' disease. We report a case of neonatal thyrotoxicosis with concurrent supraventricular tachycardia (SVT). The female infant, who was born by section due to breech delivery and meconium in the amniotic fluid at 36 weeks of gestation, presented with tachycardia on day 7. Her heart rate was between 260 and 300 beats/min, and an electrocardiogram revealed ongoing SVT. Sotalol was effective after two cardioversions in maintaining sinus rhythm. Thyroid function studies revealed hyperthyroidism in the infant, and her mother was found to have Graves' disease. Since symptoms and signs can vary, especially in preterm infants with neonatal hyperthyroidism, we want to emphasize the importance of prenatal care and follow-ups of Graves' disease associated pregnancies and management of newborns after birth.
Prenatal Evaluation and Postnatal Early Outcomes of Fetal Ventriculomegaly
(2014) Tugcu, Ali Ulas; Gulumser, Cagri; Ecevit, Ayse; Abbasoglu, Aslihan; Uysal, Nihal Sahin; Kupana, Ebru Sebnem; Yanik, Fatma Filiz; Tarcan, Aylin; https://orcid.org/0000-0002-2232-8117; https://orcid.org/0000-0001-5385-5502; 25135472; AAJ-4616-2021; AAA-9475-2020
Objective: This study aims to determine the incidence, etiology, diagnostic criteria and early outcomes of prenatally diagnosed fetal ventriculomegaly (VM). Methods: Diagnostic criteria for the fetal VM was atrial diameter of lateral ventricle measuring >= 10 mm, independent from gestational age. Results of our patients from ultrasonography (USG), karyotyping, congenital infections, and associated abnormalities were noted. Progress during pregnancy, postnatal USG results and neurobehavioral outcomes were recorded. Results: In our study, 40 subjects of fetal VM were recorded. 16 and 24 of those were bilateral (40%) and unilateral (60%) respectively. Female to male fetus ratio was 19/21 (0.9). Median gestational age at the diagnosis was 22 weeks (ranging between 16 and 34 weeks). While 21 VM subjects were isolated (52.5%) only 19 of the total were shown associated structural abnormalities in (47.5%) in addition to VM. Toxoplasmosis were diagnosed only in One subject (2.5%). Nineteen subjects had amniocentesis (47.5%) and 2 of them were showed abnormalities (10.5%) as follows; "inversion and duplication 8 (p11.2p23)" and "deletion 3". VM got back in to normal size during pregnancy in 24 subjects (24/40, 60%). Eight pregnancies were terminated (8/40) (20%). Five babies passed away during neonatal and postneonatal period. Some other structural abnormalities were diagnosed after the birth at six babies who classified as mild "isolated" VM. Conclusions: Our study revealed that amongst mild VM subjects, incidence of associated abnormalities and termination rate were higher. Although most of mild VM subjects are thought to be benign, associated abnormalities should be carefully evaluated and determined pre- and postnatally. (C) 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.