Browsing by Author "Tokmak, Naime"

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    Evaluation of brain perfusion in Alzheimer disease with perfusion computed tomography and comparison to elderly patient without dementia
    (2016) Yildirim, Tulin; Karakurum Göksel, Basak; Demir, Senay; Tokmak, Naime; Tan, Meliha; 27513264
    Background/aim: The aim of this study was to evaluate perfusion computed tomography (PCT) findings in patients with Alzheimer disease and to compare them with those of patients without dementia. Materials and methods: PCT was performed in 35 patients: 20 with Alzheimer disease (mean age, 69.7 +/- 5.5 years) and 15 control subjects (mean age, 67.5 +/- 3.5 years). Control subjects were elderly individuals with no cognitive problems who were admitted with headaches. All PCT examinations were performed on a 4-slice CT unit. The PCT analysis software program was used to calculate regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV), regional time-to-peak (rTTP) values in the bilateral frontal, temporal, and occipital cortices, and bilateral lentiform nucleus. Results: rCBF values in the bilateral frontal and temporal cortices and bilateral lentiform nucleus were significantly lower in the patients with Alzheimer disease than in the control subjects. There were no significant differences in rCBV values between Alzheimer disease and the control group. rTTP values in all cortical areas and bilateral lentiform nucleus were significantly higher in the patients with Alzheimer disease than in the control subjects. Conclusion: PCT is a rapid and reliable imaging modality for evaluating brain perfusion in Alzheimer disease.
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    Evaluation of the Ophtalmic Artery Flow Pattern with Color-Doppler Ultrasonography in the Patients with Carotid Artery Stenosis
    (2015) Demir, Senay; Akgul, Erol; Aikimbaev, Kairgeldy; Tokmak, Naime; Inal, Mehmet; Aksungur, Erol
    Purpose: To assess whether ophtalmic artery flow patterns reflect the status of cerebral circulation in patients with carotid artery stenosis. Material and Method: Twenty-four patients including 14 men and 10 women, with varying degrees of monolateral or bilateral carotid artery stenosis were included in the study. Patients' ages ranged between 32 and 79 years (mean 60). The control group was composed of 12 subjects without carotid artery stenosis who had undergone digital substaction angiography for different purposes. Digital substraction angiography and color-Doppler ultrasonography were performed in all the patients and the control group. Degrees of carotid artery stenosis and flow patterns and velocities, pulsatility and resistance indices of ophtalmic arteries of two groups were compared. Results: Significant differences in ophtalmic artery flow patterns and velocities, pulsatility and resistance indices between those patients with carotid artery stenosis of more than 70% and the control group were recorded. Conclusion: Imaging of the ophtalmic artery with color-Doppler ultrasonography is a useful and cost-effective method that reflects the status of cerebral circulation in patients with carotid artery stenosis.
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    Value of Sonographic Anterior-Posterior Renal Pelvis Measurements Before and After Voiding for Predicting Vesicoureteral Reflux in Children
    (2015) Demir, Senay; Tokmak, Naime; Cengiz, Nurcan; Noyan, Aytul; 0000-0002-4209-9075; 25545034; GPX-7059-2022; AAD-5713-2021; AAK-9310-2021
    PurposeVoiding cystourethrography (VCUG) is the gold standard for diagnosing vesicoureteral reflux (VUR), but it is important to minimize the use of VCUG because of the urinary catheterization and radiation exposure required. Ultrasound (US) observations suggest that pelvicalyceal dilatation varies according to the degree of bladder fullness in children with urinary tract infection. The aim of this study was to assess whether anterior-posterior (AP) measurements of the renal pelvis on US before and after voiding can be used as a screening tool while predicting the presence of VUR in children. MethodsThe subjects were toilet-trained children older than 4 years who required VCUG. Two groups were established based on the VCUG results: a VUR group of 40 kidney units (each unit defined as calyces and ureter) that exhibited different severities of reflux, and a control group of 68 kidney units unaffected by VUR. Prior to VCUG, US AP measurements of the renal pelvis of each kidney unit were recorded when the urinary bladder was full and again after bladder emptying. The change in AP measurement from before to after voiding was compared between the two groups. ResultsThe mean change in AP measurements from before to after voiding in the VUR group was significantly greater than that in the control group (p=0.003). ConclusionsComparing US AP measurements of the renal pelvis before and after voiding is useful for identifying children who are suspected to have VUR and thus require immediate VCUG. (c) 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:490-494 2015