Browsing by Author "Tierney, Claire"

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    A Comparison between Mygind and Kaiteki positions in administration of drops to the olfactory cleft
    (2021) Milk, Dafna G.; Khong, Grace C.; Cam, Osman H.; Alfaro-Iraheta, Fernando; Tierney, Claire; Kassem, Firas; Leong, Samuel C.; https://orcid.org/0000-0002-2785-4474; 33326692
    Objectives Topical nasal steroids are a common treatment intervention for olfactory dysfunction. Penetration of topic treatment to the olfactory cleft (OC), such as nasal drops, is greatly dependent on the position of the head when the treatment is administered. We aimed to examine the penetrance of nasal drops to the OC in two different head positions: the Mygind (lying head back) position and the Kaiteki position. Design and Setting The specimens were firstly positioned in Mygind, and thereafter in Kaiteki positions. Nasal drops mixed with blue food dye were administered into the nostrils in each of the head position. Endoscopic videos were recorded, and two blinded observers scored the extent of olfactory cleft penetration (OCP) using a 4-point scale (0 = none, 3 = heavy). Participants Twelve fresh-frozen cadaver specimens. Main outcome measures Penetration of the dye into the OC. Results The mean score of nasal drops penetrance to the OC in the Mygind position was 1.34 (standard deviation, SD = 0.92), as compared to 1.76 (SD = 0.65) in the Kaiteki position. The difference in the OCP score between the two groups was not statistically significant (P > .05). Conclusion Both Mygind and Kaiteki head positions are reasonable options for patients considering topical nasal drops for olfaction impairment. The preference of one position over the other should be determined by patient's preference and comfort.
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    Endoscopic balloon dilatation of the olfactory cleft - a feasibility study of a novel technique in cadavers
    (2021) Cam, Osman H.; Milk, Dafna Gershnabel; Alfaro Iraheta, Fernando; Khong, Grace C.; Tierney, Claire; Leong, Samuel C.; 34028462
    Objective. Smell dysfunctions are common with almost 20% percent of the population affected. There are no interventional solutions for these patients. The aim of this study is to investigate the feasibility and security of the balloon dilatation technique. Methods. This paper describes interventional steps and determines the feasibility and safety of endoscopic olfactory cleft dilatation via balloon device. We included 10 nasal cavities in the study and dilated olfactory cleft areas via balloon device. Results. We could smoothly perform the procedure and did not observe any fractures on the skull base or olfactory cleft of the cadavers after dilatation. Conclusions. A combination of this intervention with medical treatments can be promising for smell dysfunctions.