Browsing by Author "Tekindal, Agah"

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Angiopoietin-1, Angiopoietin-2, and Periostin Levels in Children with Recurrent Wheeze
(2018) Koksal, Burcu Tahire; Aydin, Beril Ozdemir; Tekindal, Agah; Ozbek, Ozlem Yilmaz
Background: Recurrent wheeze (RW) is frequent in preschool children. Wheezing phenotypes, asthma predictive index (API), and modified API (mAPI) have been described for clinical purposes. Our aim was to examine whether inflammatory markers including serum angiopoietin (Ang)-1, Ang-2, and periostin levels differ according to wheezing phenotypes and mAPI. Materials and Methods: Ninety-eight children who were <4 years of age with history of at least 4 episodes of wheezing during the past 12 months and 51 age-matched healthy controls were included in the study. Children with RW were classified according to wheezing phenotypes as episodic viral wheeze or multitrigger wheeze, and positive or negative mAPI. Blood for Ang-1, Ang-2, and periostin levels was drawn during wheezing episode-free periods. Results: Atopic children with RW (31.4 +/- 34.4 ng/mL) demonstrated higher serum Ang-1 levels than nonatopic children (16.5 +/- 13.8 ng/mL) with RW (P = 0.03). When we compared children according to wheezing phenotypes, we could not find any difference in serum Ang-1, Ang-2, and periostin levels between groups. Children with positive mAPI showed similar Ang-1, Ang-2, and periostin levels with children having negative API and healthy children. Conclusions: We have found higher serum Ang-1 levels in atopic children with RW, and this result might be explained by increased inflammation. The evidence was not strong enough to associate serum Ang-1, Ang-2, or periostin and asthma in preschool children with RW. However, Ang-1 can be a candidate for investigating its role in predicting atopic children and diagnosing atopic childhood asthma.
Cross-Cultural Adaptation, Reliability and Validity of the Turkish Version of the Lower Limb Functional Index
(2015) Duruturk, Neslihan; Tonga, Eda; Gabel, Charles Philip; Acar, Manolya; Tekindal, Agah; 0000-0002-4060-7048; 25777549; AAD-3908-2020; ACK-5152-2022
Purpose: This study aims to adapt culturally a Turkish version of the Lower Limb Functional Index (LLFI) and to determine its validity, reliability, internal consistency, measurement sensitivity and factor structure in lower limb problems. Method: The LLFI was translated into Turkish and cross-culturally adapted with a double forward-backward protocol that determined face and content validity. Individuals (n = 120) with lower limb musculoskeletal disorders completed the LLFI and Short Form-36 questionnaires and the Timed Up and Go physical test. The psychometric properties were evaluated for the all participants from patient-reported outcome measures made at baseline and repeated at day 3 to determine criterion between scores (Pearson's r), internal consistency (Cronbachs alpha) and test-retest reliability (intraclass correlation coefficient - ICC2.1). Error was determined using standard error of the measurement (SEM) and minimal detectable change at the 90% level (MDC90), while factor structure was determined using exploratory factor analysis with maximum likelihood extraction and Varimax rotation. Results: The psychometric characteristics showed strong criterion validity (r = 0.74-0.76), high internal consistency (alpha = 0.82) and high test-retest reability (ICC2.1 = 0.97). The SEM of 3.2% gave an MDC90 = 5.8%. The factor structure was uni-dimensional. Conclusions: Turkish version of LLFI was found to be valid and reliable for the measurement of lower limb function in a Turkish population.
An Examination of the Relationship Between ABO Blood Groups and Hematological Parameters
(2017) Koctekin, Belkis; Kurtoglu, Aysegul; Tekindal, Agah; Kurtoglu, Erdal; Gundogan, Nimet Unay; 0000-0001-7784-9641; GVU-6849-2022; AAD-2048-2019; AAK-4338-2021
Examining Color Discrimination Ability and Depth Perception Relationship with Farnsworth Munsell 100 Hue Test, TNO Test and Titmus Test
(2017) Koctekin, Belkis; Coban, Deniz Turgut; Unal, Ayse Cengiz; Ozen, Mehmet; Tekindal, Agah; Altintas, Aysegul Kocak; Gundogan, Nimet Unay; https://orcid.org/0000-0001-7784-9641; AAK-4338-2021
Reliability and Validity of a Turkish Language Version of the Bates-Jensen Wound Assessment Tool
(2014) Karahan, Azize; Toruner, Ebru Kilicarslan; Ceylan, Aysun; Abbasoglu, Aysel; Tekindal, Agah; Buyukgonenc, Lale; https://orcid.org/0000-0001-6698-2121; https://orcid.org/0000-0002-4060-7048; 24988512; B-8478-2015
PURPOSE: The aim of this study was to evaluate content and construct validity of a Turkish language version of the Bates Wound Assessment Tool (BWAT) as well as its internal consistency and interrater reliability. SUBJECTS AND SETTING: The study was conducted in 13 intensive care units that included patients with pressure ulcers; the units were located in a university hospital in Central Anatolia, Turkey. The sample comprised 70 nurses and 20 patients who have stage II, III, and IV pressure ulcers. METHODS: Data were collected between January and April 2011. Content validity was measured using the Davis Technique. The BWAT was scored by 2 groups, nurses with expertise in wound care and staff nurses. An expert nurse and a ward nurse conducted pressure ulcer evaluation on the same patient consecutively in order to determine interrater reliability. We also measured internal consistency via the Cronbach a. RESULTS: The content validity agreement rate was 0.82. The interrater reliability of the instrument was 0.82; its internal consistency calculated via the Cronbach alpha was 0.85. CONCLUSION: The findings of this study support the Turkish language version of the BWAT as possessing content validity, interrater reliability and internal consistency.
Screening preschool children for fine motor skills: environmental influence
(2016) Comuk-Balci, Nilay; Bayoglu, Birgül; Tekindal, Agah; Kerem-Gunel, Mintaze; Anlar, Banu; 27134406
[Purpose] The aim of this study was to investigate the influence of gender and family factors on performance in the fine motor domain of the Denver II developmental screening test. [Subjects and Methods] Data were obtained from 2038 healthy children, 999 boys (49%) and 1039 girls (51%) in four age groups: 0-24 months (57%), 25-40 months (21.1%), 41-56 months (10.4%), and 57-82 months (11.5%). [Results] Female gender, higher maternal age, especially in children older than 24 months, and higher maternal education were associated with earlier accomplishment of fine motor items. Higher socioeconomic status was correlated with fine motor skills more noticeably at young ages. [Conclusion] The results of this study support the role of environmental factors in the interpretation of fine motor test results and point to target groups for intervention, such as infants in the low socioeconomic group and preschool children of less educated mothers. Studies in different populations may reveal particular patterns that affect child development.