Browsing by Author "Tasci, Halil Ibrahim"

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Coexistence of Papillary Microcarcinoma and Hurthle Cell Adenoma: A Case of Thyroid Collision Tumor
(2022) Tasci, Halil Ibrahim; Erinanc, Hilal; Turk, Emin; Karagulle, Erdal; 0000-0003-2269-4798; AAJ-2989-2021
While thyroid cancers are usually present one type of cancer in the thyroid gland, rarely different thyroid cancers may found in one or two different lobes of the thyroid gland at the same time. A 70-years-old female patient presented with a long-standing neck swelling, especially on the left side, which was more prominent, recently increasing in size and causing shortness of breath. Due to tracheal compression and diagnosis of multi-nodular goiter, total thyroidectomy was performed. Histopathological examination revealed a thyroid collision tumor with papillary microcarcinoma on the right and hurtle cell adenoma on the left side. Due to its rarity, clinicians encountered difficulties in the diagnosis and treatment of thyroid collision tumors. We believe that to be aware of these rare entities by encouraging clinicians to report such cases enable to more solid conclusions to diagnosis and management of collision tumors.
Factors Affecting Recurrence of Idiopathic Granulomatous Mastitis
(2022) Tasci, Halil Ibrahim; Turk, Emin; Erinanc, Ozgur Hilal; Erkan, Serkan; Gundogdu, Ramazan; Karagulle, Erdal; https://orcid.org/0000-0003-2269-4798; 35108784; AAJ-2989-2021
Objective: To investigate factors that may have an effect on recurrence by retrospectively analysing the data of patients who were followed up and treated for idiopathic granulomatous mastitis in this clinic. Study Design: Analytic study. Place and Duration of Study: Department of General Surgery, Faculty of Medicine, Baskent University, Konya and Adana Practice and Research Hospitals between January 2010 and January 2021. Methodology: The data of patients who were histopathologically diagnosed with granulomatous mastitis were retrospectively analysed. The patients included in the study were divided into two groups: Recurrence (Group 1) and non-recurrence (Group 2). Patients with underlying etiological factors that may cause granulomatous inflammation such as infection, trauma, tuberculosis, sarcoidosis, and autoimmune disease were excluded from the study. The effects of other parameters (involvement area, followup duration, the time from the onset of complaints to diagnosis, side of involvement, breastfeeding, oral contraceptive use, redness, ulceration and/or discharge, preoperative histopathological diagnosis, diagnosis by any of the preoperative imaging techniques, preferred treatment method) on recurrence, were statistically analysed. Results: Furthermore, the analysis results showed no significant difference between the groups with and without recurrence with regard to any of the other variables such as follow-up period, size of the involvement area, presenting complaints, breast-feeding,preferred treatment alternative (steroid, steroid + surgery, surgery), and preferred surgical technique (p>0.05). The time from the onset of complaints to diagnosis was significantly longer in the recurrence group (p=0.001). In addition, the frequency of oral contraceptive use was statistically significantly higher in the recurrence group (Odds ratio=7.6, p=0.044). Conclusion: The results of this study suggest that early diagnosis could prevent recurrence in patients with idiopathic granulomatous mastitis. Prospective randomised controlled studies are needed to support this thought.
The Impact of COVID-19 Infection on Hemodialysis Patients vs Kidney Transplant Patients
(2023) Tasci, Halil Ibrahim; 38131360
AIM: AS in the whole world, there has been a decrease in the number of both cadaveric and living-donor kidney transplants in our country due to the COVID-19 pandemic. This study aimed at comparing the data of patients who previously underwent a kidney transplant in our clinic and patients on hemodialysis treatment and were diagnosed with COVID-19 during their follow-ups to find answer to the question "Should we postpone kidney transplants during the pandemic or perform transplants as soon as possible?". MATERIAL AND METHOD: Among those diagnosed with COVID-19 during follow-ups between March 2020 and March 2021 and treated on an inpatient or outpatient basis, the data of patients who previously underwent a kidney transplant in Baskent University Faculty of Medicine, Department of Transplantation, Konya Practice and Research Hospital and hemodialysis patients followed up by the Nephrology Clinic were retrospectively analyzed. RESULTS: In our study, intensive care stay (Group 1:48.8%, Group 2: 40.4%, P=.34), intubation requirement (Group 1: 35%, Group 2: 34.6%, P=.96) and mortality (Group 1: 36.3%, Group 2: 34%, P=.84) rate was higher in the hemodialysis group, although no statistically significant difference was found. CONCLUSION: All this literature information and our study suggests that mortality rates were statistically similar or lower for transplant group. So it is unnecessary to delay kidney transplantation in patients with appropriate indications.
Neuroendocrine Tumour of the Gallbladder Diagnosed after Cholecystectomy
(2022) Tasci, Halil Ibrahim; Coskunoglu, Esra Zeynep; Turk, Emin; Karagulle, Erdal; 0000-0003-2269-4798; AAJ-2989-2021
Gallbladder cancer is a rare but aggressive malignancy. Neuroendocrine tumour of the gallbladder make up 2-3% of all the gallbladder tumour. A 67-year female patient underwent laparoscopic cholecystectomy because of symptomatic cholelithiasis and the histopathology revealed a neuroendocrine tumour of the gallbladder, stage pT2a. The patient's imaging study for metastasis workup were normal. A radical cholecystectomy procedure was planned as the tumour stage was pT2a. Postoperative chemotherapy and/ or radiotherapy were recommended. The patient, who had comorbidities, was refused both surgery and other treatment alternatives. The patient's one-year clinical, laboratory, and radiological follow-up did not reveal any findings of recurrence or metastasis. There is no standardised staging system for neuroendocrine tumours of the gallbladder since the number of such cases is quite limited. Guidelines are also insufficient. Multi-centred and large studies are needed in order to develop standardisation in treatment, prognosis, and factors affecting survival.
A Rare Case: Primary Mucinous Cystic Neoplasm Of The Gallbladder
(2021) Tasci, Halil Ibrahim; Erinanc, Ozgur Hilal; Turk, Emin; Karagulle, Erdal
Cystic lesions originating from the gallbladder are very rare. Mucinous cystic neoplasms of the liver and biliary system principally occur in the liver, followed by the extrahepatic biliary system. Only a few case reports were reported primarily in the gallbladder. A 63-year-old woman was admitted to our hospital with complaints of pain in the right upper abdomen, increasing after meals, and abdominal discomfort. A laparoscopic cholecystectomy was performed. Macroscopically, the cyst was localized in the serosa of the fundus. Based on immunohistochemical examination, the cyst was diagnosed as primary mucinous cystic neoplasia of the gallbladder. Although it is very rare, mucinous cystic neoplasia should be kept in mind when dealing with cystic lesions of the gallbladder. Due to serious associated problems such as the risk of malignant transformation or bile duct obstruction, particularly in larger cysts, a cholecystectomy is mandatory.
The role of neutrophil-to-lymphocyte ratio in predicting disease progression and emergency surgery indication in benign intestinal obstructions
(2022) Tasci, Halil Ibrahim; 36043932
BACKGROUND: The physiological response of the immune system to various stress factors results in an increase in neutrophil count and a decrease in lymphocyte count. In the light of this information, some studies have suggested using the ratio of these two parameters as an infection marker. The aim of this study was to investigate the role of neutrophil-to-lymphocyte ratio (NLR) derived from complete blood count, a very cost-effective and rapidly measurable parameter, in predicting the urgency of the surgical indication and disease progression in intestinal obstructions secondary to benign causes. METHODS: The data of patients who were admitted with the diagnosis of intestinal obstruction secondary to benign causes and underwent surgical intervention between January 2010 and January 2021 in Baskent University, Faculty of Medicine, Department of General Surgery, Konya Practice and Research Hospital were retrospectively analyzed. The data of 109 patients who met the study criteria and were included in the study were statistically analyzed. The correlation of admission NLR with factors indicating the severity of the disease such as intraoperatively detected ischemia, perforation, resection requirement, post-operative morbidity and mortality, and length of hospital stay was examined. Moreover, the diagnostic value of the NLR was compared with that of other infection mark-ers (such as C-reactive protein [CRP] and leukocyte). RESULTS: It was observed that the high NLR during admission to the hospital due to benign intestinal obstruction causes signif-icantly increased the risk of ischemia, resection requirement, post-operative complications, and mortality during surgery (p<0.05). Furthermore, increased NLR was found to be associated with prolonged hospitalization. In correlation analysis, consistent with the literature, a positive correlation was found between NLR and hospitalization time (p=0.03), CRP value (p<0.001), ischemia (p<0.001), perforation (p=0.007), presence of post-operative complications (p=0.009), and mortality (p=0.002). CONCLUSION: Our results show that the NLR has a very important role in predicting the course of the disease and surgical in-dication in benign intestinal obstructions.