Browsing by Author "Soy, Ebru H. Ayvazoglu"

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Application of Ileobladder for Clinical Kidney Transplantation: Two Case Reports
(2018) Haberal, Mehmet; Kirnap, Mahir; Akdur, Aydincan; Soy, Ebru H. Ayvazoglu; Yildirim, Sedat; Moray, Gokhan; Kayhan, Zeynep; Torgay, Adnan; 0000-0002-3462-7632; 0000-0002-8726-3369; 0000-0002-0993-9917; 0000-0002-5735-4315; 0000-0003-2498-7287; 0000-0003-0579-1115; 0000-0002-6829-3300; AAJ-8097-2021; AAH-9198-2019; AAA-3068-2021; AAC-5566-2019; AAF-4610-2019; AAE-1041-2021; AAJ-4623-2021; AAJ-5221-2021
Assessment Of Long-Term Outcomes Of Pediatric Liver Transplant Recipients
(2022) Karakaya, Emre; Akdur, Aydincan; Soy, Ebru H. Ayvazoglu; Ozcay, Figen; Moray, Gokhan; Haberal, Mehmet; https://orcid.org/0000-0002-0993-9917; https://orcid.org/0000-0002-3462-7632; AAC-5566-2019; AAJ-8097-2021
ASSESSMENT OF MIDDLE EAR MECHANICS, INTERNAL EAR ACOUSTICAL EMISSION MEASUREMENTS AND HEARING IN RENAL TRANSPLANT RECIPIENTS
(2020) Oz, Isilay; Soy, Ebru H. Ayvazoglu; Sayin, Burak; Ozluoglu, Levent; Haberal, Mehmet
Candidaemia among Adult Solid Organ Transplant Recipients
(2018) Yesilkaya, Aysegul; Demirkaya, Melike H.; Ozalp, Onur; Soy, Ebru H. Ayvazoglu; Azap, Ozlem Kurt; Arslan, Hande; Haberal, Mehmet; https://orcid.org/0000-0003-0225-6416; https://orcid.org/0000-0003-4284-2225; https://orcid.org/0000-0002-0993-9917; https://orcid.org/0000-0002-3171-8926; https://orcid.org/0000-0002-5708-7915; https://orcid.org/0000-0002-3462-7632; A-8902-2013; GMW-6437-2022; AAC-5566-2019; AAK-4089-2021; ABG-7034-2021; AAJ-8097-2021
Changes in ocular biometric parameters after renal transplantation
(2020) Aksoy, Mustafa; Asena, Leyla; Gungor, Sirel Gur; Soy, Ebru H. Ayvazoglu; Akman, Ahmet; Haberal, Mehmet; 0000-0002-3462-7632; 0000-0002-0993-9917; 0000-0001-6178-8362; 0000-0002-6848-203X; 0000-0003-1513-7686; 32415655; AAJ-8097-2021; AAC-5566-2019; E-5914-2016; AAD-5967-2021
Purpose This study aimed to investigate the changes in postoperative ocular biometric parameters in end-stage renal disease patients who underwent renal transplantation. Material and methods This retrospective study included a total of 33 eyes of 33 patients. The ocular biometric measurements which were evaluated were axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), corneal keratometry (K1 and K2), degree of astigmatism, lens thickness (LT), and intraocular pressure (IOP). Refractive prediction error (RE) was calculated before and after renal transplantation using the same diopter (D) for intraocular lens (IOL) power calculation and evaluated for potential cataract surgery. Results The study included 15 male (45%) and 18 female (55%) patients. Mean patient age was 31.55 +/- 8.24 (range: 18-49 years). In the comparison of preoperative and 1-month postoperative measurements, there was a statistically significant difference in AL, LT, ACD, and CCT (p < 0.001). There was no statistically significant difference between K1, K2, and astigmatism measurements (p = 0.72; p = 0.35; p = 0.62, respectively). There was no statistically significant difference in RE (p = 0.61-Holladay 2). Conclusion While renal transplantation surgery does not lead to significant changes in astigmatism, predicted refractive error, corneal keratometry, or intraocular pressure, it causes significant decrease in axial length, lens thickness, and central corneal thickness and significant increase in anterior chamber depth. However, these changes do not result in significant changes in IOL power calculation in planned cataract surgery.
CHANGES IN OCULAR BIOMETRIC PARAMETERS AFTER RENAL TRANSPLANTATION
(2020) Aksoy, Mustafa; Asena, Leyla; Gungor, Sirel Gur; Soy, Ebru H. Ayvazoglu; Haberal, Mehmet A.
CLINICAL IMPACT OF COMPLEMENT DEPOSITION FINDINGS ON BIOPSIES IN ACUTE REJECTION EPISODES OF PEDIATRIC RENAL TRANSPLANT PATIENTS
(2020) Gulleroglu, Kaan; Baskin, Esra; Ozdemir, B. Handan; Yilmaz, Aysun Caltik; Soy, Ebru H. Ayvazoglu; Moray, Gokhan; Haberal, Mehmet A.
Clinical Outcomes Of Liver Transplantation For Patients Over 60 Years Old; A Single Center Experience
(2021) Akdur, Aydincan; Karakaya, Emre; Soy, Ebru H. Ayvazoglu; Karakayali, Feza; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; 0000-0002-8726-3369; 0000-0002-3462-7632; AAC-5566-2019; AAA-3068-2021; AAJ-8097-2021
Comparision of Influenza and Covid-19 Infections in Solid Organ Transplant Recipients
(2022) Yalcin, Tugba Yanik; Yuce, Gulbahar Darilmaz; Soy, Ebru H. Ayvazoglu; Azap, Ozlem Kurt; Arslan, Hande; Haberal, Mehmet; 0000-0002-3462-7632; AAJ-8097-2021; JBS-4193-2023
Comparison of Mortality Rates in Patients Waiting for Liver Transplant and Patients With Colorectal Metastatic Tumors
(2022) Erkent, Murathan; Aydin, H. Onur; Tezcaner, Tugan; Avci, Tevfik; Kavasoglu, Lara; Soy, Ebru H. Ayvazoglu; Yildirim, Sedat; Haberal, Mehmet; 0000-0002-3592-5092; 0000-0002-0664-5147; 0000-0002-0993-9917; 0000-0002-3462-7632; 35352633; CAA-2756-2022; AAJ-8219-2021; AAC-5566-2019; AAJ-8097-2021
Objectives: We aimed to identify outcomes of liver surgery in patients with hepatocellular carcinoma and colorectal cancer, which result in primary and secondary liver tumors. Materials and Methods: Our study included 51 patients with colorectal cancer and liver metastases and 63 patients with hepatocellular carcinoma who were prepared for liver transplant due to cirrhosis who underwent hepatic resection or local ablation treatments; patients were seen between January 2011 and December 2021. Results: Most patients with colorectal cancer were men (58.8%). Mean age was 65.76 +/- 13.818 years (range, 27-88 y). Most patients had planned, elective surgery (86.3%). Neoadjuvant chemotherapy was administered to 58.8% of patients. The most common location of metastasis in the liver was in the right lobe (43.1%), and the most common surgery was low anterior resection (17 patients). During simultaneous liver surgery, 31 patients required metastasectomy and 7 patients required radiofrequency ablation plus metastasectomy. No deaths occurred in the early posttransplant period, and cumulative survival was 82.624 +/- 7.962 months. Disease-free survival was 45.2 +/- 7.495 months. Most patients with hepatocellular carcinoma were men (82.5%). Mean age was 58.73 +/- 17.428 years. Hepatocellular carcinoma lesions were mostly located in both the right and left lobes (23.8%). In the hepatocellular cancer group, 60.3% had transarterial chemoembolization and 42.9% had radiofrequency ablation. The primary surgical resection was metastasectomy (17.9%) because of multiple localized lesions. Median follow-up was 22 months (range, 1-126 mo). Overall survival was 101.898 +/- 7.169 months, with 10-year overall survival of 38%. Disease-free survival was 74.081 +/- 8.732 months, with 1-year and 5-year disease-free survival of 90.5% and 54%. Conclusions: Better survival was shown in patients with hepatocellular carcinoma than in patients with colorectal cancer. Therefore, more aggressive treatment options, as used in hepatocellular carcinoma, including liver transplant, may be options for patients with colorectal cancer.
Comparison of Recipients with Early and Later Presentation Polyomavirus Nephropathy (PVN) with Regard to Histological Findings and Graft Survival: What is the Influence of CD4/CD8 Ration on the Presenting Time of PVN
(2018) Ozdemir, B. Handan; Ayva, Sebnem; Terzi, Aysen; Atilgan, Alev Ok; Akcay, Eda; Soy, Ebru H. Ayvazoglu; Acar, F. Nurhan Ozdemir; Haberal, Mehmet; 0000-0002-7528-3557; 0000-0002-2280-8778; 0000-0002-1225-1320; 0000-0001-8595-8880; 0000-0001-6831-9585; 0000-0002-0993-9917; 0000-0002-5682-0943; 0000-0002-3462-7632; X-8540-2019; AAK-1967-2021; F-7546-2013; AAK-3333-2021; AAK-1960-2021; AAC-5566-2019; AAK-1697-2021; AAJ-8097-2021
Coronavirus Disease (COVID-19) in Kidney and Liver Transplant Patients: A Single-Center Experience
(2020) Akdur, Aydincan; Karakaya, Emre; Soy, Ebru H. Ayvazoglu; Alshalabi, Omar; Kirnap, Mahir; Arslan, Hande; Ulubay, Gaye; Hekimoglu, Koray; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; 0000-0002-0805-0841; 0000-0002-3462-7632; 0000-0003-2478-9985; 0000-0003-2498-7287; 0000-0002-8726-3369; 0000-0002-4879-7974; 32519617; AAC-5566-2019; AAD-9097-2021; AAJ-8097-2021; AAB-5064-2021; AAE-1041-2021; AAA-3068-2021; AAD-5466-2021
Objectives: The novel 2019 coronavirus (COVID-19) was first described in December 2019 in Wuhan, China and subsequently announced as a pandemic on March 12, 2020. In several studies, solid-organ transplant recipients were reported to have higher risk for COVID-19. Here, we aimed to determine the frequency of COVID-19 in our kidney and liver transplant patients. Materials and Methods: Our study included 583 transplant patients who were admitted to our outpatient transplant clinics and emergency departments between March 1 and May 1, 2020. Seventy-four of them were liver transplant recipients (46 male, 28 female, of which 14 were pediatric and 60 were adult patients) and 509 of them were kidney transplant recipients (347 male, 162 female, of which 16 were pediatric and 493 were adult patients). We retrospectively evaluated demographic characteristics, currently used immunosuppressant treatment, present complaints, treatment and diagnosis of comorbid diseases, and results of COVID-19 tests. Results: Of 583 transplant recipients, 538 were seen in our outpatient transplant clinics and 45 were seen in our emergency departments. Of these, 18 patients who had had cough and fever were evaluated by respiratory clinic doctors, and nasopharyngeal swab samples were taken. One kidney transplant recipient had a positive COVID-19 test; he was followed with home isolation. He received treatment with hydroxychloroquine (400 mg/day). The other 17 patients had negative tests. There were no mortalities due to COVID-19. Conclusions: Transplant patients also got affected during the COVID-19 pandemic. According to the data of our centers, this effect is not much more different from the normal population. We recommend that transplant recipients should be warned in terms of personal hygiene and should be closely monitored by organ transplant centers. If there is an indication for hospitalization, they should be followed in an isolated unit, with no aggressive changes made to immunosuppressive doses unless necessary
CYTOMEGALOVIRUS (CMV) INFECTION INDUCES AN ANGIOGENIC RESPONSE THROUGH HEPATIC STELLATE CELLS (HSCS) AND LEADS TO EARLY POST-TRANSPLANT LIVER FIBROSIS (LF) AND POOR GRAFT SURVIVAL
(2019) Ozdemir, B. Handan; Ozgun, Gonca; Soy, Ebru H. Ayvazoglu; Haberal, Nihan; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; AAC-5566-2019
Cytomegalovirus Infection Induces an Angiogenic Response through Hepatic Stellate Cells and Leads to Early Post-Transplant Liver Fibrosis and Poor Graft Survival
(2019) Ozdemir, B. Handan; Ozgun, Gonca; Soy, Ebru H. Ayvazoglu; Haberal, Nihan; Moray, Gokhan; Haberal, Mehmet A.
DECEASED-DONOR TRANSPLANTATION ACTIVITIES IN TURKEY
(2020) Soy, Ebru H. Ayvazoglu; Akdur, Aydincan; Karakayali, Feza; Moray, Gokhan; Yildirim, Sedat; Haberal, Mehmet A.
Early post-transplant blood transfusions and graft outcome in pediatric renal transplant recipients
(2019) Baskin, Esra; Kazanci, Ozlem; Uslu, Nihal; Gulleroglu, Kaan; Soy, Ebru H. Ayvazoglu; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; 0000-0003-4361-8508; AAC-5566-2019; ABC-5258-2020; B-5785-2018
EARLY POST-TRANSPLANT BLOOD TRANSFUSIONS AND GRAFT OUTCOME IN PEDIATRIC RENAL TRANSPLANT RECIPIENTS
(2019) Baskin, Esra; Kazanci, Ozlem; Uslu, Nihal; Gulleroglu, Kaan; Soy, Ebru H. Ayvazoglu; Moray, Gokhan; Haberal, Mehmet; 0000-0002-0993-9917; AAC-5566-2019
Early Postoperative Infections After Liver Transplant
(2018) Soy, Ebru H. Ayvazoglu; Akdur, Aydincan; Yildirim, Sedat; Arslan, Hande; Haberal, Mehmet; 0000-0002-0993-9917; 0000-0002-8726-3369; 0000-0002-5735-4315; 0000-0002-5708-7915; 0000-0002-3462-7632; 29528013; AAC-5566-2019; AAA-3068-2021; AAF-4610-2019; ABG-7034-2021; AAJ-8097-2021
Objectives: Despite surgical advances and effective prophylactic strategies in liver transplant, infection is still a major cause of morbidity and mortality. Up to 80% of liver recipients will develop at least 1 infection during the first year after liver transplant. The spectrum and manifestations of these infections are broad and variable. Their diagnosis and treatment are often delayed because immunosuppressive therapy diminishes inflammatory responses. However, if an infection is not identified early enough and treated properly, it can have devastating consequences. In addition, prophylactic approaches remain controversial. Our aim was to review our early postoperative infection management after liver transplant. Materials and Methods: We retrospectively evaluated infections that occurred during the first hospital stay of transplant patients. Infections were grouped as surgical site and nonsurgical site infections. Consequences and treatment protocols of infections were stratified according to the Clavien scale. Results: Between December 1988 and January 2017, we performed 561 liver transplants at our center (patient age range, 6 months to 64 years), which included 401 living-donor (72%) and 160 deceased-donor (28%) liver transplants. Early postoperative infections were detected in 131 patients (23.3%), comprising 67 surgical site (51%), 56 nonsurgical site (43%), and 8 combined surgical and nonsurgical site infections (6%). Although no mortalities occurred in patients with single nonsurgical or surgical site infections, there were 4 mortalities in patients with combined surgical and nonsurgical site infections. In the 4 other patients with combined infections, 3 patients required endoscopic or radiologic intervention and 1 recovered from single-organ dysfunction. Conclusions: Initiation of appropriate prophylactic and therapeutic protocols at the right time decreases morbidity and mortality due to infection in liver transplant recipients. Increased understanding and effective approaches to prevent infection are essential to improving both graft and recipient survival.
EFFECT OF LIVER TRANSPLANTATION ON NEUROLOGICAL MANIFESTATIONS AND BRAIN MAGNETIC RESONANCE IMAGING FINDINGS IN WILSON DISEASE
(2019) Soy, Ebru H. Ayvazoglu; Ocal, Ruhsen; Benli, Sibel; Donmez, Fuldem; Agildere, Muhtesem; Ocal, Serkan; Haberal, Mehmet; 0000-0002-0993-9917; AAC-5566-2019; AAB-5802-2020
The effect of static magnetic field on partial thickness burn wound healing
(2019) Soy, Ebru H. Ayvazoglu; Aydin, Huseyin Onur; Terzi, Aysen; Ekici, Yahya; Moray, Gokhan
Aim: During the past decades, there has been a substantial and growing evidence that static magnetic fields (SMF) and pulsed electromagnetic fields (EMF) can both produce satisfying therapeutic effects on various disorders. There have been researches about the efficacy of SMF in wound healing. However, there is no any investigation about the efficacy of SMF in burn wound healing. In this experimental study, we aimed to investigate the efficacy of SMF in partial thickness burn wound in rats. Material and Method: Forty male Sprague-Dawley male rats were used in the experiment. The modification of Sawada's bum model was applied. In Group1 magnets, in Group2 non-magnetic bars were placed vertically to the burn wound. In Group3 magnets, in Group4 non-magnetic bars were placed horizontally to the burn wound. The wound heating is evaluated by gross wound healing rate and histopathological examination. Results: In study groups, wound healing was faster, granulation with fibroblast migration was earlier, collagen production and neovascularisation were more than control groups. We found no relationship between wound healing and vector direction. Discussion: According to these results static magnetic field can be used in clinic to promote the healing in patients with burns. Especially, in cases that have no chance for grafting, to decrease complications and increase the survival, the static magnetic field can be an alternative.