Browsing by Author "Soames, Roger"

Now showing 1 - 3 of 3

The effect of alendronate sodium on trabecular bone structure in an osteoporotic rat model
(2017) Ozsahin, Esin Tokmak; Cam, Burcu; Dere, Fahri; Kurkcu, Mehmet; Evruke, Cuneyt; Soames, Roger; Oguz, Ozkan; 31453446
Objectives: This study aims to investigate the effect of alendronate sodium on trabecular bone structure in an osteoporotic rat model. Materials and methods: Between May 2006 and July 2006, 60 female Wistar Albino rats aged three months were randomly allocated to three groups: sham operated receiving no treatment (Shm); ovariectomized-alendronate receiving 1 mg/kg/day alendronate sodium (Ovx-A), and ovariectomized-vehicle receiving 1 mL/kg/day physiological saline (Ovx-PS). Both Ovx groups received treatment through gastric gavage for 56 days. Results: Densitometric measurements showed that bone mineral density decreased in the Ovx-PS and increased in Ovx-A groups (p<0.05). Biomechanical measurements showed a decrease in the breaking force in the Ovx-PS group and an increase in the Ovx-A group (p<0.05). Histomorphometric measurements showed that the Shm group had normal trabecular structure, while the Ovx-PS group had a less well-formed trabecular structure with a loss in the trabecular number and thickness and a corresponding increase in the trabecular spacing (p<0.05). In the Ovx-A group, there was an improvement in the trabecular structure with an increase in the trabecular number and thickness and a loss in the trabecular space (p<0.05). Conclusion: Our study results suggest that alendronate sodium is a valuable treatment agent for osteoporosis in postmenopausal women.
Evaluation of Face Shape in Turkish Individuals
(2016) Ozsahin, Esin; Kizilkanat, Emine; Boyan, Neslihan; Soames, Roger; Oguz, Ozkan
The aim of this study was to determine the types of face shape in the Turkish population. Knowledge on face shape is important in anthropology and for planning medical procedures such as in aesthetic, maxillofacial and orthodontic surgery. The study group consisted of 1003 healthy subjects (470 male, 533 female) aged 18-68 years. Mean height, weight and body mass index (BMI) were 1.74 m, 78.65 Kg, 25.80 +/- 3.50 kg/m(2) and 1.62 m, 60.55 kg, 22.87 +/- 3.49 kg/m(2) in males and females, respectively. Face length (FL; the distance from nasion to gnathion) and face width (FW; bizygomatic breadth) were measured, from which a Prosopic Index (PI) was determined using the following formula: (PI=FL/FW x 100). The types of face shape were classified according to Banister's classification Type I (hypereuryprosopic), Type II (euryprosopic), Type III (mesoprosopic), Type IV (leptoprosopic), Type V (hyperleptoprosopic) in both males and females. PI was 84.31 (FL: 12.07 cm; FW: 14.34 cm) in males and 85.25 (FL: 11.30 cm; FW: 13.28 cm) in females. In males and females Type I face shape was observed in 18.1 % and 15.6 %; Type II in 35.3 % and 34.3 %; Type III in 33.2 % and 34.3 %; Type IV in 8.7 % and 11.8 %; and Type V in 4.7 % and 3.9 %, respectively. The determination of types of face shape as presented in this study may be useful for aesthetic surgical procedures as well as medical and anthropological investigations.
Morphometric Measurement and Types of Articular Facets on the Talus and Calcaneus in an Anatolian Population
(2016) Boyan, Neslihan; Ozsahin, Esin; Kizilkanat, Emine; Soames, Roger; Oguz, Ozkan
Anatomical variations in terms of ligamentous attachments, articulations and bony morphology are common in the subtalar region. The shape of the articular facets of the talus and calcaneus and their relationship to each other are important for joint function and surgical procedures. In this study an assessment of the morphology of the articular facets of the talus and calcaneus, in an Anatolian population, was undertaken. 49 tali and 57 calcanei from Anatolian adults of unknown gender were examined. The types of articular facets on the talus and calcaneus were determined using the following classification: Type A1, the distance between the anterior and middle facets was less than 2 mm; Type A2, the distance between the anterior and middle facets was 2-5 mm; Type A3, the distance between the anterior and middle facets was more than 5 mm; Type A4, there was only one articular facet; Type B1, the separation between the anterior and middle facets was not complete; Type B2, separation of the anterior and middle facets was present; Type C, no separation between the anterior, middle and posterior facets was present, i.e. there was one articular facet. In addition, the anteroposterior length and width of the talus and calcaneus, together with the width, length and depth of sulcus tali and sulcus calcanei were determined. Left and right tali, respectively, displayed the folowing types of articular facet: A1, 0 %, 0 %; A2, 0 %, 3,4 %; A3, 0 %, 0 %; A4, 0 %, 0 %; B1, 60 %, 51,8 %; and B2, 40 %, 44.8 %. Articular facets on left and right calcanei, respectively, were: A1, 10 %, 7.4 %; A2, 10 %, 14.8 %; A3, 16.7 %, 11.1 %; A4, 3.3 %, 3.7 %; B1, 30 %, 22.2 %; B2, 30 %, 40.8 %. The length and width of left and right tali were 50.5 +/- 3.81 mm and 39.5 +/- 2.97 mm, and 53.1 +/- 4.38 mm and 39.3 +/- 3.66 mm, respectively. The width, length and depth of left and right sulcus tali were: 5.2 +/- 1.09 mm, 21.7 +/- 2.73 mm and 5.7 +/- 0.84 mm, and 6.1 +/- 2.05 mm, 21.1 +/- 3.66 mm and 5.7 +/- 1.52 mm, respectively. For left and right calcanei length and width were; 76.1 +/- 5.44 mm 44.0 +/- 3.97 mm, and 75.7 +/- 6.76 mm and 45.9 +/- 4.21 mm, respectively. The width, length and depth of left and right sulcus calcanei were: 6.4 +/- 1.19 mm, 31.9 +/- 2.76 mm and 4.0 +/- 0.81 mm, and 5.5 +/- 1.00 mm, 32.4 +/- 3.23 mm and 4.4 +/- 1.05 mm, respectively. The articular facets on both the talus and calcaneus in the Anatolian population studied was predominantly type B. This observations is similar to previous reports conducted in America, India and Africa, but differ from those undertaken in Europe. A knowledge of variations of the articular facets of the talus and calcaneus provides a valuable road map for orthopaedic surgeons, as well as others involved in foot rehabilitation.