Browsing by Author "Simsek, Cem"

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Comparison of The Mechanical Properties of The Anterior Lens Capsule in Senile Cataract, Senile Cataract with Trypan Blue Application, and Pseudoexfoliation Syndrome
(2017) Simsek, Cem; Oto, Sibel; Yilmaz, Gursel; Altinors, Dilek Dursun; Akman, Ahmet; Gungor, Sirel Gur; https://orcid.org/0000-0001-8003-745X; https://orcid.org/0000-0003-0171-4200; https://orcid.org/0000-0002-2589-7294; https://orcid.org/0000-0001-5223-0279; https://orcid.org/0000-0001-6178-8362; 28917406; N-8970-2018; AAJ-4668-2021; AAK-6987-2021; AAK-8077-2021; AAD-5967-2021
Purpose: To evaluate the elastic modulus, hardness, and mechanical properties of the anterior lens capsule in different types of cataract and to assess the correlation with age. Setting: Baskent University Hospital, Department of Ophthalmology, Ankara, Turkey. Design: Prospective comparative study. Methods: Patients were divided into 3 groups. Group 1 comprised patients with senile cataract, Group 2 patients had pseudoexfoliation (PXF) syndrome, and Group 3 patients had dye-enhanced cataract surgery. The capsules were analyzed using a nanoindentation device. Young's modulus of elasticity was measured by the Oliver-Pharr method and capsule hardness by the Martens method. Results: The study comprised 72 patients, 24 per group. The mean Young's modulus was 7.53 GPa +/- 1.07 (SD) in Group 1, 6.01 +/- 1.25 GPa in Group 2, and 8.12 +/- 0.98 GPa in Group 3. The capsules in Group 2 were more elastic than in Group 1 and Group 3 (P < .001). The capsules in Group 3 had lower elasticity than in Group 1, although the difference was not significant (P = .94). The mean capsule stiffness was 326.41 +/- 98.40 MPa in Group 1, 210.5 +/- 52.32 MPa in Group 2, and 315.54 +/- 163.15 MPa in Group 3. The lens capsules in Group 2 were less stiff than those in Group 1 and Group 3 (P < .001). Conclusions: Capsule thickness was positively correlated with increasing age in all groups. The anterior lens capsules of patients with PXF had more elasticity and less stiffness than the other groups. Intracameral trypan blue application had no effect on capsule elasticity and stiffness. (C) 2017 ASCRS and ESCRS
Etiology of Cirrhosis in Turkey: A National Cohort Study
(2021) Yildirim, Abdullah Emre; Ucbilek, Enver; Oruncu, M. Berk; Turan, Ilker; Demir, Mehmet; Koksal, Aydin; Uyanikoglu, Ahmet; Yilmaz, Nimet; Akarsu, Mesut; Tozlu, Mukaddes; Avcioglu, Ufuk; Haktaniyan, Busra; Aladag, Murat; Yolacan, Ramazan; Toka, Bilal; Kefeli, Ayse; Ormeci, Asli Ciftcibasi; Haciyev, Ferid; Balci, Hatice Rizaoglu; Yurci, Mustafa Alper; Balaban, Hatice Yasemin; Fidan, Sami; Gunduz, Feyza; Gencdal, Genco; Simsek, Cem; Ebik, Berat; Cavus, Bilger; Karatay, Eylem; Sezgin, Gulten Can; Yaras, Serkan; Karabulut, Umit; Gokturk, Huseyin Savas; Uzel, Ali; Ekin, Nazim; Barutcu, Sezgin; Cosar, Arif Mansur; Keklikkiran, Caglayan; Batu, Kerim Deniz; Alkim, Huseyin; Acar, Sencan; Yogun, Yasar; Harputluoglu, Murat; Yalcin, Kendal; Gunsar, Fulya; Sezgin, Orhan; Akarca, Ulus; Kaymakoglu, Sabahattin; Karasu, Abdullah Zeki; Ozdogan, Osman Cavit; Idilman, Ramazan
Non-Contact and Contact Tonometry in Corneal Edema
(2016) Gungor, Sirel Gur; Akman, Ahmet; Kucukoduk, Ali; Asena, Leyla; Simsek, Cem; Yazici, Ayse Canan; https://orcid.org/0000-0001-6178-8362; https://orcid.org/0000-0001-8024-4758; https://orcid.org/0000-0002-6848-203X; https://orcid.org/0000-0001-8003-745X; https://orcid.org/0000-0002-3132-242X; 26583789; AAD-5967-2021; E-5914-2016; N-8970-2018; AAS-6810-2021
Purpose To compare the intraocular pressure (IOP) values by Goldmann applanation tonometry (GAT) and Reichert 7 CR noncontact tonometry (R7CR-NCT) in patients with postsurgical corneal edema and to examine the impact of postoperative corneal edema on these values. Methods Forty-six patients with grade 4 and 5 cataracts were included in this study. Intraocular pressure was measured using GAT and R7CR-NCT before and 1 day after phacoemulsification. Central corneal thickness (CCT) was determined before and after surgery to quantify postsurgical corneal edema. The R7CR-NCT provided a Goldmann-correlated IOP (IOPg) and corneal-compensated IOP (IOPcc). Results The CCT increased significantly 1 day after surgery (the mean preoperative CCT, 543.5 25.4 m; the mean postoperative CCT, 681.5 +/- 19.8 m; p < 0.001), a mean increase of 26.7%. The preoperative R7CR-NCT measurements (the mean IOPcc, 18.8 +/- 5.6 mm Hg; the mean IOPg, 17.8 +/- 4.5 mm Hg) were significantly higher than GAT measurements (the mean GAT-IOP, 16.0 +/- 3.4 mm Hg) (p < 0.001). On postoperative day 1, the R7CR-NCT measurement (the mean IOPcc, 27.0 +/- 9.8 mm Hg; the mean IOPg, 25.1 +/- 8.9 mm Hg) were significantly higher than GAT measurements (the mean GAT-IOP, 18.3 +/- 7.9 mm Hg) (p < 0.001). The difference between postoperative R7CR-NCT and GAT-IOP values were significantly higher than the difference between preoperative R7CR-NCT and GAT-IOP values (p < 0.001 for both IOPcc to GAT-IOP and IOPg to GAT-IOP). The difference between postoperative IOPcc and GAT-IOP was significantly correlated to the change in CCT (r = 0.526, p < 0.001). Similarly, the difference between postoperative IOPg and GAT-IOP was significantly correlated to the change in CCT (r = 0.536, p < 0.001). Conclusions The R7CR-NCT IOP values were high in patients with postsurgical intensive corneal edema. Consequently, the difference between R7CR-NCT IOP and GAT-IOP increased in edematous corneas.