Browsing by Author "Shaheen, Faissal A. M."

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Middle East Society for Organ Transplantation (MESOT) Transplant Registry
(Başkent Üniversitesi, 2004-12) Haberal, Mehmet A.; Shaheen, Faissal A. M.; Stephan, Antoine; Ghods, Ahad J.; Al-Rohani, Muhamed; Mousawi, Mustafa Al; Mohsin, Nabil; Ben, Taieb; Bakr, Adel; Rizvi, Adibul Hasan
During the seventies, sporadic renal transplants were performed in few MESOT-region countries, mainly Turkey, Iran, Egypt, and Lebanon. Since the introduction of cyclosporine in the early eighties, transplantation has become the preferred therapeutic modality for end-stage renal failure. In 1986, the Islamic theologians (Al Aloma) issued what became known as the Amman declaration, in which they accepted brain death and retrieval and transplantation of organs from living and cadaveric donors. Based on this and similar declarations, all Middle Eastern countries except Egypt passed laws that allow cadaveric transplantation and regulate live donations. Iran, Turkey, Saudi Arabia, Kuwait, Tunisia, Jordan, and Lebanon all have current active cadaveric programs and perform liver, heart, pancreas, and lung transplants. More than 5088 renal transplants/year are performed in the region with Iran leading with 1600. The cumulative number of renal transplant patients is now nearly 60,000. With a 2003 population of 600,682,175, the rate/million for renal transplantation in the MESOT region is a mere 9/million. Rates of renal transplantation range from 31/million in some countries to 0 in others. The major obstacle in establishing an accurate number of transplants is “tourist transplantation,” in which the same transplanted patients are registered in different countries. Although cadaveric programs have been active for more than 10 years, live-related and nonrelated transplants account for nearly 85% of the total transplants. The data presented were collected from MESOT representatives in the region and from publications. For proper compilation of the registry, a format is being proposed that will be presented at the Congress for review and adaptation. Even with the limited resources in the region, immunosuppressive drugs for induction and maintenance therapy are available and are used. Costs for transplantation and immunosuppressive therapy are either totally or heavily supported by governmental agencies.
Organ Donations from Deceased Persons in the Saudi Arabian Population
(Başkent Üniversitesi, 2005-06) Al Shehri, Saleh; Shaheen, Faissal A. M.; Al-Khader, Abdulla A.
Methods: We examined next-of-kin records of Saudi brain dead persons who had been approached for consent for donation during 1998. These same next of kin were approached in 2004 and asked to fill out a questionnaire examining demographics, awareness, and emotions regarding their decision to donate a family member’s organ(s). In addition, data related to the deceased persons also were recorded. Results: During 1998, 41 Saudi next of kin had been approached for permission to obtain organs from their deceased relatives. Of these, 16 consented and 25 did not. We obtained responses from all the consenters (group 1) and from 16 of the nonconsenters (group 2). The consenters were more educated; had positive feelings about donation and still do; and had keener knowledge regarding organ donation, religious standpoints about donation, and the results of transplantation. Conclusions: The results demonstrate that consent for donation depends on prior knowledge and awareness of the various aspects of organ donation. Public education methods used to encourage organ donation need review. We found no differences in economic status or age between consenters and nonconsenters. The relationship between the deceased person and the next of kin does not appear to play a role in determining consent or refusal. On the other hand, consent was less likely when death was caused by a motor vehicle accident than it when other factors led to death.
The Reality of Inadequate Patient Care and the Need for a Global Action Framework in Organ Donation and Transplantation
(2022) Dominguez-Gil, Beatriz; Ascher, Nancy L.; Fadhil, Riadh A. S.; Muller, Elmi; Cantarovich, Marcelo; Ahn, Curie; Berenguer, Marina; Egawa, Hiroto; Gondolesi, Gabriel E.; Haberal, Mehmet; Harris, David; Hirose, Ryutaro; Ilbawi, Andre; Jha, Vivekanand; Lopez-Fraga, Marta; Madera, Sergio Andres; Najafizadeh, Katayoun; O'Connell, Philip J.; Rahmel, Axel; Shaheen, Faissal A. M.; Twahir, Ahmed; Van Assche, Kristof; Wang, Haibo; Haraldsson, Boerje; Chatzixiros, Efstratios; Delmonico, Francis L.; Busic, Mirela; 36279558
Background. Transplant therapy is considered the best and often the only available treatment for thousands of patients with organ failure that results from communicable and noncommunicable diseases. The number of annual organ transplants is insufficient for the worldwide need. Methods. We elaborate the proceedings of the workshop entitled "The Role of Science in the Development of International Standards of Organ Donation and Transplantation," organized by the Pontifical Academy of Sciences and cosponsored by the World Health Organization in June 2021. Results. We detail the urgency and importance of achieving national self-sufficiency in organ transplantation as a public health priority and an important contributor to reaching relevant targets of the United Nations Agenda for Sustainable Development. It details the elements of a global action framework intended for countries at every level of economic development to facilitate either the establishment or enhancement of transplant activity. It sets forth a proposed plan, by addressing the technical considerations for developing and optimizing organ transplantation from both deceased and living organ donors and the regulatory oversight of practices. Conclusions. This document can be used in governmental and policy circles as a call to action and as a checklist for actions needed to enable organ transplantation as treatment for organ failure.