Browsing by Author "Sancakli, O."

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Effects Of Elimination Diets And Clinical Findings On Mothers' Anxiety In Infants With Food Allergy With Non-Life-Threatening Reactions
(2022) Sancakli, O.; Aslan, A.Akin; 34797040
Background. In food allergies (FA), the current treatment is eliminating the responsible food from the diet until tolerance develops. We aimed to determine the effects of the mother's elimination diets and clinical findings on the mothers' anxiety in infants with food allergy (FA) with non-lift-threatening reactions. Methods. Our study included 100 infants with FA and 35 healthy infants as control. A data form was prepared to collect information about the infants' and their mothers' socio-demographic characteristics, clinical findings, features of the mother's elimination diet, and FA-related internet search. State-Trait Anxiety Inventory (STAI) was applied to all mothers. Results. The STAI (state anxiety and trait anxiety) scores of the mothers of the infants with FA were higher than the control group (p < 0.001, p = 0.001, respectively). Of the infants with FA, 51% had food protein-induced allergic proctocolitis (FPIAP), 29% had atopic dermatitis (AD), 20% had urticaria-angioedema (U/AE). It was found that state anxiety scores were higher in mothers whose child had FPIAP, who had multiple food eliminations, who followed the allergy groups on social media, and who made the elimination diet herself (p = 0.008, p = 0.048, p < 0.001, p = 0.001, respectively). Conclusions. The state anxiety and trait anxiety of the mothers of the infants with FA were higher than the control group, and the state anxiety scores were higher especially in the mothers of infants with FPIAP and multiple food elimination.
A novel mutation c.2010delG of CLCN5 gene associated with Dent disease-1 in an 11-year-old male with nephrolithiasis and nephrocalcinosis
(2018) Kulu, B.; Sancakli, O.; Sakallioglu, O.
Dent's disease-1 (CLCN5 gene) is a rare X-linked recessive tubulopathy characterized by low molecular weight proteinuria, hypercalciuria, nephrolcalcinosis or nephrolithiasis, proximal tubular dysfunction and renal failure in adulthood. Females are carriers and usually mildly affected. We present an 11-year-old child with nephrocalcinosis and nephrolithiasis with c.2010delG (or p.Asp671fs) mutation in CLCN5 gene which had not previously been reported in the Dent's disease-1. © 2018 National Academy of Pediatric Science and Innovation. All rights reserved.
A novel mutation of Dent's disease in an 11-year-old male with nephrolithiasis and nephrocalcinosis
(2018) Sancakli, O.; Kulu, B.; Sakallioglu, O.; 0000-0003-2489-4021; 29756720; AAD-5613-2021
Dent's disease is a rare X-linked recessive tubulopathy characterized by low molecular weight (LMW) proteinuria, hypercalciuria, nephrolcalcinosis or nephrolithiasis, proximal tubular dysfunction and renal failure in adulthood. Females are carriers and usually mildly affected. Progression to end-stage renal failure are at the 3rd-5th decades of life in 30-80% of affected males. In the absence of therapy targeting for the molecular defect, the current care of patients with Dent’s disease is supportive, focusing on the prevention of nephrolithiasis and nephrocalcinosis. We present an 11-year-old child with nephrocalcinosis and nephrolithiasis caused by a new mutation at CLCN5 gene. © 2018 Sociedad Argentina de Pediatria. All rights reserved.