Browsing by Author "Ozkoc, Esma Erguner"

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Content-Based Search on Time-Series Microarray Databases Using Cluster-Based Fingerprints
(2017) Ozkoc, Esma Erguner; Ogul, Hasan; AAG-1506-2021
Background: The rapid growth of gene expression databases has created a need for content-based searches as an alternative to unstructured database queries using keyword- or metadata-based searches. Content-based searching is the ability to retrieve all experiments with similar gene expression patterns in a database regardless of the biological annotations provided for these experiments. Objective: While this concept is still in its infancy in a general context, in this study we focus on applying it to a specific subset of gene expression datasets, by only querying experiments involving time-series expression profiles. Method: To this end, we propose a novel experiment fingerprinting scheme obtained by clustering expression profiles, for content-based searching of time-series microarray experiments. To determine the retrieval ability of the proposed scheme, we performed a simulated information retrieval task on a large set of microarray experiments gathered from a public repository. The relevance between any two experiments was then defined using their commonalities based on annotated disease associations. Results and Conclusion: The results showed that relevant experiments can be more successfully retrieved using this new method compared with traditional differential expression-based methods.
The Intellectual Structure of the Information Systems Field: Research Styles and Publication Patterns of North American and European Paradigms
(2022) Ozkoc, Esma Erguner; Kefkir, Teoman Ahmet; Kirkbesoglu, Erdem; https://orcid.org/0000-0002-6781-9753; AAG-1506-2021; ABI-3973-2020
This paper identifies the researches that have had the greatest impact on the Information Systems (IS) discipline and analyses the changes that have taken place in the intellectual structure of this discipline within the ongoing paradigmatic debates between Europe and North America. The methodology applies citation analysis and social network analysis to the articles published in four European and North American journals with the highest impact factors in the IS field. The findings of the study reveal a significant difference between the research styles and publication patterns of European and North American research traditions.
Molecular Biology Inspired Mutual Authentication Schemes for Wireless Body Area Network
(2021) Ozkoc, Esma Erguner; Mannion, Mike
As the use of Wireless Body Area Network (WBAN) becomes widespread, concerns about the security of the data they produce and transmit are also increasing. One of the basic security requirement for WBAN communication include authentication. In this study, a certificate-less mutual authentication scheme is proposed. The scheme was developed using pseudo-DNA cryptography techniques (due to its features such as randomness and rule less, easily generated and accessible, similarity to the binary system and no need for high-tech laboratory conditions) in addition to modern cryptography techniques, to increases the level of security without adding additional computational costs to the system.