Browsing by Author "Ozbek, Namik"

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Cardiac Transplant in a Child with Recurrent Thrombosis Due to Congenital Thrombophilic Mutations
(Başkent Üniversitesi, 2009-09) Ozbek, Namik; Aslamaci, Sait; Ozkan, Suleyman; Atac, F. Belgin; Ozcobanoglu, Salih; Uguz, Emrah; Sezgin, Atilla; Verdi, Hasibe
A modified Blalock-Taussig shunt had been implanted 3 times to treat cyanosis to a patient who has uncorrectable congenital cardiac deformity. We repaired the entire pulmonary artery, from one hilus to the other, to prevent future stenosis while making cardiac transplant. Our patient was also heterozygous for 2 thrombophilic mutations: methylene tetrahydrofolate reductase C677T and Factor V A4070G. Congenital risk factors should be evaluated in patients who have experienced a thromboembolic event before cardiac surery.
Is there any association between thrombotic risk factors and veno-oclusive disease in childhood allogeneic hematopoietic stem cell transplantation?
(2019) Cihan, Meric Kaymak; Atac, Fatma Belgin; Bilir, Ozlem Arman; Aksu, Tekin; Kanbur, Serife Mehtap; Ozbek, Namik
Ophthalmologic Findings in Children with Leukemia: A Single-Center Study
(2016) Orhan, Betul; Malbora, Baris; Bayar, Sezin Akca; Avci, Zekai; Alioglu, Bulent; Ozbek, Namik; 27800262
Objectives: Ophthalmologic disease in patients with acute leukemia occurs due to primary leukemic infiltration (involvement), or secondary to the disease and its treatment. In recent years the life expectancy of acute leukemia patients has increased with the advent of modern therapies. The present study aimed to determine the incidence of ocular manifestations in children with acute leukemia. Materials and Methods: The study included 120 patients diagnosed with acute leukemia at Baskent University Hospital, Pediatric Hematology Department between 1995 and 2010. All the patients were examined by an ophthalmologist via direct and indirect ophthalmoscopy. Results: Among the patients, 83 (69.2%) were diagnosed with acute lymphoblastic leukemia, 35 (29.1%) with acute myeloblastic leukemia, and 2 (1.7%) with mixed-lineage leukemia. In all, 58 ophthalmic manifestations were noted in 41 patients (34.2%). In our patients, 12 ophthalmologic involvements were present at admission and 46 ocular findings occurred during follow-up. The incidence of these manifestations increased with age. Conclusion: Ophthalmologic manifestations were not correlated with gender, hematological parameters at disease onset, type of leukemia, or the frequency of relapse and survival. To more clearly determine the effect of ophthalmologic manifestations on the prognosis of leukemia, larger scale and multi-center studies are needed.
Severe Adenovirus Infection Associated with Hemophagocytic Lymphohistiocytosis
(2014) Hosnut, Ferda Ozbay; Ozcay, Figen; Malbora, Baris; Hizli, Samil; Ozbek, Namik; 24764742