Browsing by Author "Otgun, Ibrahim"

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The Effect of Intraperitoneal N-Acetylcysteine on Postoperative Adhesions in Rat Models
(2017) Asian, Gizem Inal; Otgun, Ibrahim; Acer, Tugba; Tepeoglu, Merih; Hicsonmez, Akgun; https://orcid.org/0000-0002-9894-8005; 28874629; AAK-5222-2021
ATM: In this study, we researched the effect of local administration of N-acetylcysteine (NAC) on postoperative intra-abdominal adhesion formation in the rat models. METHODS: 20 female Wistar Albino rats which were 5-7 months old are used for the study. The rats were divided into two equal groups. Group one was administered saline solution (n=10) while group two was administered NAC (n=10) after caecal abrasion. They were dissected on postoperative tenth day and were examined macroscopically and microscopically for the adhesion formation. Intraperitoneal adhesion formation was scored blinded with Evans model. The most adherent bowel section was excised for histopathologic examination. Mann Whitney U test were used for statistical analysis. RESULTS: In Group one, all rats have had adhesions. None of the rats in Group two had either severe inflammatory cell reaction or dense interstitial fibrosis. Macroscopic adhesion formation and microscopic inflammatory cell reaction and interstitial fibrosis formation after surgery were less at the group two (NAC applied) (p<0.05, p<0.05, p<0.05). CONCLUSION: We believe that the intraperitoneal single dose usage of NAC may be promising for decreasing the postoperative intraabdominal adhesions.
Effectiveness of the Gamma Probe in Childhood Parathyroidectomy: Retrospective Study
(2020) Caglar, Ozgur; Otgun, Ibrahim; Comert, Hatice Yalcin; Gencoglu, Arzu; Baskin, Esra; 0000-0003-4631-1683; 0000-0003-4361-8508; 31966944; ABG-1864-2020; B-5785-2018
Background There are few reports about parathyroidectomy due to secondary hyperparathyroidism in patients with end-stage renal failure in the literature. We aimed to evaluate the surgical treatment methods and the results of patients who were operated for secondary hyperparathyroidism with end-stage renal disease in our center. Method Sixteen patients with the diagnosis of secondary hyperparathyroidism were treated surgically in our center. Demographical data, laboratory findings, and imagining methods were all examined. The effect of the Technetium 99m methoxyisobutylisonitrile (Tc-99m-MIBI) probe sensitive to gamma rays detection was also evaluated to locate and identify all the parathyroid glands during the operation. Results Eleven of the patients underwent intravenous (IV) Tc-99m MIBI preoperatively and a gamma probe was detected during surgery. The gamma probe was not used in five patients. Four parathyroid glands were removed in eight (72.7%) out of 11 patients with gamma probes and three parathyroid glands were found in three patients. Total parathyroidectomy and parathyroid autoimplantation were made to eight patients who had removed four glands, subtotal parathyroidectomy was done for the other patients. On a comparison of laboratory findings before and after the surgery, there was a significant relationship between the decrease of serum parathyroid hormone and calcium levels (p<0.05). Conclusion Total parathyroidectomy and parathyroid autoimplantation is the most efficient and safe mode of management for secondary parathyroidism patients. During the surgery, using a probe sensitive to gamma rays detection may also help the surgeon. Thus, unnecessary dissections to prevent the presence of atypical parathyroid glands are prevented.
Foreign body punctured the spleen: An incidental diagnosis
(2017) Guney, Lutfi Hakan; Inal-Aslan, Gizem; Otgun, Ibrahim; Hicsonmez, Akgun; 000-0002-2500-5401; 29168374; AAK-6241-2021
A foreign body can enter the body via penetration through the skin. In the presented case, a broken syringe needle was found and removed from the splenic parenchyma. In order to prevent such iatrogenic injuries, which could have fatal consequences, the hospital staff must give particular care in the handling of sharp FBs.
Primary Ovarian Malignant Melanoma Arising in Teratomatous Component of Mixed- Germ Cell Tumor in a Child: Case report
(2014) Ozyoruk, Derya; Demir, Haci Ahmet; Emir, Suna; Haberal, Asuman Nihan; Bugdayci, Meral; Otgun, Ibrahim; https://orcid.org/0000-0001-9852-9911; 24499012; AAK-4587-2021
Primary ovarian malignant melanoma arising in teratomatous component of germ cell tumors is seen extremely rare with most reports being only of single cases and small series in reproductive aged woman and mostly from cystic teratoma, whereas information on pediatric presentation is sparse. This case is reported for being extremely rare tumor.