Browsing by Author "Onay, Emel Olga"

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Assessment of alternative emergency treatments for symptomatic irreversible pulpitis: a randomized clinical trial
(2018) Birgul, Eren; Onay, Emel Olga; Ungor, Mete; 0000-0002-3276-0843; 0000-0001-5800-8871; 28857203; B-4134-2008; ABE-9724-2021
Aim To evaluate three emergency procedures for their ability to alleviate clinical symptoms associated with symptomatic teeth having signs of (at least) partial irreversible pulpitis. Methodology Sixty-six maxillary and mandibular molars were randomly assigned to a total pulpectomy group (TP; n = 22), partial pulpectomy group (PP; n = 22) or pulpotomy group (P; n = 22). Procedure durations were recorded. Patients answered a questionnaire on daily analgesic requirements and about clinical symptoms (pain intensity, chewing sensitivity and thermal sensitivity) after the anaesthetic effect had disappeared (Day 0) and on Days 1, 3 and 7 post-treatment. Results The total pulpectomy group was associated with the longest procedures (median, 24 min), followed by the partial pulpectomy and pulpotomy groups (P < 0.001 for all). In all three groups, pain intensity, thermal sensitivity and chewing sensitivity decreased significantly from the preoperative time-point to Day 7 (P < 0.001 for all). The total pulpectomy group reported greater reductions in pain intensity than the pulpotomy group between Days 0 and 7, Days 1 and 3, and Days 1 and 7 (P < 0.001 for all). No other intergroup differences were noted regarding reductions in pain intensity, and none were observed with respect to changes in prevalence of thermal sensitivity and chewing sensitivity. There were also no significant intergroup differences regarding the analgesic requirements throughout the 7days. Conclusion As emergency treatments for teeth having signs of irreversible pulpitis, pulpotomy, partial pulpectomy and total pulpectomy were comparable with respect to relieving clinical symptoms. Pulpotomy may be preferred because it requires significantly less time and is a simple technique that relieves symptoms quickly and effectively.
Comparison of Three Final Irrigation Activation Techniques: Effects on Canal Cleanness, Smear Layer Removal, and Dentinal Tubule Penetration of Two Root Canal Sealers
(2017) Turkel, Elmas; Onay, Emel Olga; Ungor, Mete; 0000-0001-5800-8871; 28437194; B-4134-2008
Objective: The aim of this study was to compare three final irrigation activation techniques with respect to their effects on debridement efficacy, smear layer removal, and dentinal tubule penetration of two different root canal sealers. Background data: Different applications to improve the delivery of irrigating solutions within the root canal system are currently being investigated, as not all of the mechanisms and effects of these techniques have been clearly identified. Materials and methods: One hundred forty-two single-rooted teeth were randomly divided into a control group and three experimental groups based on the irrigant activation technique used: EndoVac (EV) system, photon-induced photoacoustic streaming (PIPS), and conventional syringe irrigation (CSI). Thirteen specimens from each experimental group were evaluated for debris and smear layer removal using scanning electron microscopy. The remaining 30 specimens per group were divided into two subgroups according to the root canal sealer used: AH Plus and TotalFill BC. The maximum depth and total percentage of sealer penetration were measured using confocal laser scanning microscopy. Results: PIPS resulted in significantly less debris in the middle third of the root canal compared with CSI (p<0.01). There were no significant differences among CSI, EV, and PIPS concerning debris removal at coronal and apical levels or smear layer removal at all levels (p>0.05). TotalFill BC use after final irrigation with EV and CSI at 2mm or PIPS at 5mm exhibited a significantly higher percentage of sealer penetration than that with AH Plus (p<0.05). When AH Plus was used, PIPS allowed deeper sealer penetration than CSI at 2mm (p<0.05). Conclusions: The effects of EV, PIPS, and CSI on debridement efficacy, smear layer removal, and dentinal tubule penetration were almost comparable. TotalFill BC showed superior tubular penetration than AH Plus.
Effect of Er,Cr:YSGG laser irradiation on apical sealing ability of calcium silicate-containing endodontic materials in root-end cavities
(2014) Onay, Emel Olga; Gogos, Christos; Ungor, Mete; Economides, Nikolaos; Lyssaris, Vasileios; Ogus, Ersin; Lambrianidis, Theodoros; 25087664
The aim of this research was to evaluate the apical sealing abilities of 60 root-end cavities filled with mineral trioxide aggregate (MTA) and iRoot BP cements after treated with either 17% EDTA solution or Er,Cr:YSGG laser irradiation. After the filling procedure, apical leakage quantity was measured at 4 weeks using a fluid filtration method. One root from each group was processed for scanning electron microscopy and energy dispersive X-ray spectroscopy analyses. Both EDTA/MTA and laser irradiation/MTA combinations showed significantly lower microleakage than EDTA/iRoot BP and laser irradiation/iRoot BP combinations (p<0.05). Between groups of the same filling material, there were no significant differences among specimens treated with EDTA or laser (p>0.05). Both MTA and iRoot-BP demonstrated tag-like structures within the dentinal tubules when used in conjunction with EDTA.
The evaluation of endodontic flare-ups and their relationship to various risk factors
(2015) Onay, Emel Olga; Ungor, Mete; Yazici, A.Canan; 26577095
Background: To evaluate the incidence of flare-ups and identify the risk factors including age, gender, tooth type, number of root canals, initial diagnosis, the type of irrigation regimen, treatment modality and the number of visits, in patients who received root canal treatment from January 2002 to January 2008. Methods: Records of 1819 teeth belonging to 1410 patients treated by 1 endodontics specialist during 6-year period were kept. Patient, tooth, and treatment characteristics were evaluated and the relationships between these characteristics and flare-ups were studied. Statistical analysis was carried out by using Pearson Chi-square test, Fisher's Exact test, and Binary Logistic regression analyses. Results: The incidence of flare-ups was 59 (3.2 %) out of 1819 teeth that received endodontic therapy. Pulpal necrosis without periapical pathosis was the most common indication for flare-up (6 %) (p < 0.01). Teeth undergoing multiple visits had a higher risk of developing flare-ups compared to those with single appointments (OR: 3.14, CI: 1.414-7.009, p < 0.01). There were also no statistically significant differences in the incidence of flare-ups regarding to age, gender, tooth type, number of root canals, treatment modality, and the irrigation solutions that used during the treatment. Conclusions: The incidence of flare-up is minimal when teeth are treated in one visit. Absence of a periapical lesion in necrotic teeth is a significant risk factor for flare-ups.
Incidence of root canal treatment of second molars following adjacent impacted third molar extraction
(2016) Oguz, Yener; Soydan, Sidika Sinem; Onay, Emel Olga; Cubuk, Secil; 30894952
Background/purpose: The aim of this study was to evaluate the incidence of requirement for root canal treatment of adjacent second molars following the surgical extraction of an impacted third molar. Materials and methods: The dental records of 6323 consecutive patients who had impacted third molars removed surgically were evaluated and the incidence of postoperative root canal treatment requirement of adjacent second molars was determined. Patients who required root canal treatment of neighboring second molars were accepted as the study group, while the remaining patients were accepted as a control group. Sex, age at the time of the operation, localization of third molar, the depth of impaction, angulation of the tooth, and the professional experience of the surgeon performing the operation were evaluated from patient records. Results: The incidence of requirement of root canal treatment for second molars following a neighboring impacted third molar extraction was 0.17% (11/6323) and invariably occurred in the mandible. The mean age of the study group was found to be significantly higher than the control group (31 years vs. 23 years). The years of professional experience of the surgeons was significantly lower in the study group than in the control group. Conclusion: Although the incidence is minimal, iatrogenic subluxation injuries occurring during the surgical removal of impacted third molars can lead to pulpal complications and a requirement for root canal treatment of adjacent second molars. Copyright (C) 2015, Association for Dental Sciences of the Republic of China. Published by Elsevier Taiwan LLC.
Odontogenic effects of two calcium silicate-based biomaterials in human dental pulp cells
(2018) Onay, Emel Olga; Yurtcu, Erkan; Terzi, Yunus Kasim; Ungor, Mete; Oguz, Yener; Sahin, Feride İffet; 30070078
Background. The goal of treating exposed pulp with an appropriate pulp capping material is to promote the dentinogenic potential of the pulpal cells. There have been recent attempts to develop more effective pulp-capping materials. Objectives. The aim of this study was to evaluate the effect of newly developed calcium silicate-based material on odontogenic differentiation of primary human dental pulp cells (HDPCs), in comparison with a contemporary calcium silicate-based material. Material and methods. Human dental pulp cells isolated from dental pulps were cultured in standard culture conditions in Dulbecco's Modified Eagle's Medium (DMEM) and then the effects of Micro-Mega mineral trioxide aggregate (MM-MTA) (Micro-Mega, Besancon, France) and ProRoot MTA (MTA) (Dentsply Sirona, Tulsa, USA) (positive control) were evaluated on HDPCs at 1, 7 and 14 days. Untreated cells were used as a negative control. Odontoblastic differentiation was assessed by alkaline phosphatase (ALP) activity. Runtrelated transcription factor 2 (RUNX2), alkaline phosphatase liver/bone/kidney (ALPL), bone morphogenetic protein 2 (BMP2), dentin sialophosphoprotein (DSPP), and Distal-less homeobox 3 (DLX3), as odontoblastic/ osteoblastic expression markers, were evaluated by semi-quantitative real-time polymerase chain reaction (RT-PCR) analysis. Calcium levels of culture media were also determined. Results. The MM-MTA group significantly increased the expression of BMP2 compared with that of the MTA group at 3 different time periods (p < 0.05). The up-regulation of ALPL between day 1 and 14 and the up-regulation of DSPP between day 7 and 14 were significant in both groups (p < 0.05). Micro-Mega MTA and MTA exhibited similar messenger RNA (mRNA) expression levels of ALPL, DSPP, RUNX2, DLX3, and ALP activities, as well as calcium levels. Conclusions. Based on the cell responses observed in this study, MM-MTA might be used efficiently in dental pulp therapy as a potential alternative to MTA.