Browsing by Author "Okten, Sabri Berkem"

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Evaluation of pregnancy rates in infertile women after application of ovulation induction and intrauterine insemination
(2020) Okten, Sabri Berkem; Dolgun, Zehra Nihal; Ugurel, Vedat; Elter, Koray
Purpose: The aim of this studywas to investigate the effects of these factors on pregnancy rates in infertile patients following ovulation induction and intrauterine insemination. Materials and Methods: The study was performed retrospectively that investigated examination reports and laboratory results of 201 infertile patients with unexplained infertility, male factor and anovulation. Women were subdivided into two groups according to the ovary-stimulating agent used as gonadotropin or clomiphene citrate. A semen sample was obtained from all men participants. Results: There were 239 cycles of unexplained infertility (77.9%), 39 cycles in ovulatory dysfunction (12.7%) and 29 cycles in male factor (9.4%) groups. The clinical pregnancy rates per cycle according to infertility type were found as 18.4% (n:44) for unexplained infertility, 17.9% (n:7) for ovulatory dysfunction and 13.8% (n:4) for malefactor. In regression analyses, follicle (diameter>10mm) count on the day of hCG administration and inseminated total motile sperm count (ITMSC) were independently affected pregnancy rate. ITMSC area value under the curve (0.63) was significantly different from 0.5. Conclusion: Follicle count on the day of hCG administration and ITMSC independently affect the pregnancy rate. Additionally, the intrauterine insemination method should be attempted in appropriate cases that have an acceptable successful pregnancy rate.
Proteinuria in preeclampsia: is it important?
(2018) Okten, Sabri Berkem; Ozkara, Atilla; Kaya, Aski Ellibes; Basbug, Alper; Dogan, Ozan; Caglar, Mete; Kumru, Selahattin; 0000-0001-7473-761X; 30084477
Objectives: Our aim is to evaluate the laboratory results arid proteinuria levels of preeclamptic women arid their relationships to maternal and fetal outcomes. Material and methods: One hundred preeclamptic pregnant women who gave birth in our clinic between 2013 and 2015 were included in our study retrospectively. The data collected from the patients included gestational week, age, gravidity, parity, abortus history, blood pressure, biochemical parameters, delivery method, maternal hospitalization time, cesarean indication, complications, blood products required, plasmapheresis use and dialysis need. The details about the newborns were recorded retrospectively. The relationships between preeclampsia signs and maternal and neonatal outcomes were analyzed. The protein amounts were analyzed via 24-hour collected urine analyses and spot urine analyses. Results: A statistically significant positive correlation was observed between neonatal intensive care unit needs and proteinuria levels. Fetal growth restriction, respiratory distress syndrome and sepsis were observed as the level of proteinuria increased, but the result was not statistically significant. Eclampsia was observed only in patients with massive proteinuria, and it was statistically significant. An increase in cesarean sections, placental abruptions, antihypertensive drug needs and blood product replacement rates was observed as the amount of proteinuria increased in preeclamptic women, but the results were not statistically significant. Conclusions: The severity of preeclampsia cannot be determined by the level of proteinuria. However, when massive proteinuria is detected, the clinician should be more cautious about maternal and fetal complications.
The Role of Personality Traits on Mode of Delivery
(2021) Okten, Sabri Berkem; Gunduz, Anil; Sencelikel, Tugce; Desteli, Guldeniz; Gunduz, Elvan Basak Usta; Bildaci, Tevfik Berk; 0000-0001-7473-761X; 0000-0002-5159-238X; 0000-0002-3883-1964; 33541178
Purpose The aim of this study is to understand the motives behind CS requests in nulliparous women in their late pregnancy better and to investigate if specific personality traits affect the maternal decision on mode of delivery. Material and Method This prospective study was conducted with 70 healthy, nulliparous parturient with singleton pregnancies. Women at their 28-32. weeks of gestation were asked to fill a socio-demographic data form and the questionnaires; Personality Belief Questionnaire - Short Form (PBQ-SF) and The Childbirth Attitudes Questionnaire (CAQ). After delivery, all the results of pre-filled questionnaires and women's mode of delivery were analyzed and compared. Results There were significant differences in personality types; dependent (p = 0.033), passive-aggressive (p = 0.031), obsessive-compulsive (p = 0.001), antisocial (p = 0.014), narcissistic (p = 0.014) and borderline (p = 0.014) between vaginal delivery and CS groups. The CAQ scores of the mothers who requested CS were significantly higher (p:0.007). Weak but significant positive relation was found between total CAQ scores and avoidant (p = 0.022), dependent (p = 0.034), passive-aggressive (p = 0.040), narcissistic (p = 0,006), schizoid (p = 0.007), paranoid (p = 0.007) and borderline (p = 0.007) personality types. Conclusion This is the first study that investigates the relationship between mode of delivery and personality traits according to the Diagnostic and Statistical Manual of Mental Disorders (DSM) and cognitive behavioral perspective in the literature. These personality traits can be carried at a level that is not clinically significant to create an obvious pathology, yet they might play a role as the motives behind the apparent reasons for women who request CS. Understanding women's motives and attitudes for childbirth during their pregnancy may help healthcare providers to tailor women's approach to childbirth to avoid unnecessary CS.
Salivary Leptin and Chemerin; a novel way of gestational diabetes screening
(2020) Okten, Sabri Berkem; Bildaci, Tevfik Berk; 0000-0001-7473-761X; 32274942
Introduction: Oral glucose tolerance testing (OGTT) is the recommended approach for the diagnosis of gestational diabetes mellitus (GDM). Leptin and chemerin are two examples of hormones from adipokine family, which mostly takes part in glucose metabolism and inflammatory processes. We aim to find a possible new and tolerable screening technique for GDM using salivary levels of leptin and chemerin. Material and method: Saliva samples of pregnant patients, on their 24-28th weeks of gestation, are collected via saliva collection kit. Leptin and chemerin ELISA tests were run from serum samples being hold at -80 degrees C following their thawing session. Patients are divided into two groups depending on their GDM status. OGTT results of patients are compared with their ELISA results. Results: ELISA study for leptin showed an insignificant difference between patients with GDM and patients without where the values were 0.44 +/- 0.33 and 0.34 +/- 0.24 respectively (p: 0.155). Chemerin study revealed a significant difference between patients with GDM and without 631.06 +/- 344.42, 334.81 +/- 244.91 respectively (p < .001). Conclusion: Leptin and chemerin can be detected in saliva. Chemerin levels are significantly higher in patients with GDM, thus this knowledge can be used to develop a new screening method for OGTT.