Browsing by Author "Kurt, Bahar"

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Effect of Pulmonary Functions on Survival in Patients with Operable Non-small Cell Lung Cancer
    (2022) Cihanbeylerden, Melek; Yumrukuz, Merve; Kurt, Bahar; Tuccar, Cise; Safak, Cagla; 35546696
    Objective: To investigate the prognostic importance of pulmonary functions and their effect on survival in patients with operable non-small cell lung cancer (NSCLC), who underwent surgical resection and/or received medical treatment. Study Design: Cohort study. Study Design: Cohort study. Place and Duration of Study: University of Health Sciences, Diskapi Training and Research Hospital, Ankara, Turkey, between June 2013 and March 2020. Methodology: The study included a total of 70 patients diagnosed with non-small cell lung cancer (NSCLC), comprising 35 who underwent surgical treatment and 35 who were treated medically. The effects of age, gender, additional comorbidities, smoking status, complications after surgery and/or radiotherapy, and pulmonary function test values on survival were investigated. Results: The median overall survival time of the patients was 1973 +/- 769.1 (466-3.480) days. According to the univariate Cox regression analysis, the preoperative and postoperative values of the forced expiratory volume in 1 second were not important risk factors affecting survival (p=0.752 and p=0.878) respectively. A statistically significant difference was observed in survival probability between the patients with and without coronary artery disease (CAD) (p=0.005). There was also a statistically significant difference between the Eastern Cooperative Oncology Group (ECOG) performance groups in terms of survival probability (p<0.001). Conclusion: There was no relationship between pulmonary functions and survival in patients with operable NSCLC, but this evaluation should be undertaken in larger patient groups. This study demonstrated the importance of patients' performance status and comorbidities, such as CAD in survival.
  • No Thumbnail Available
    Item
    Frequency of Direct Oral Anticoagulants Usage in Acute Pulmonary Thromboembolism Treatment in Turkey (TUPEDO)
    (2022) Tanriverdi, Elif; Tutar, Nuri; Senturk, Aysegul; Bahadir, Ayse; Aksel, Nimet; Yetkin, Nur Aleyna; Karadeniz, Gulistan; Cetin, Nazli; Tabaru, Ali; Yildirim, Binnaz Zeynep; Sen, Hatice Selimoglu; Ozcelik, Neslihan; Ozsari, Emine; Uzer, Fatih; Cicek, Tugba; Esendagli, Dorina; Hocanli, Iclal; Kocak, Nagihan Durmus; Tapan, Utku; Kurt, Bahar; Arinc, Sibel; Kavas, Murat; Sahin, Fusun; Ergun, Dilek; Ucar, Elif Yilmazel; Kilic, Talat; Gulmez, Inci; Emre, Julide Celdir; Dogan, Deniz; Ozdemir, Fatma; Duger, Mustafa; Alzafer, Suha; Yarar, Esra; Unat, Damla Serce; Salik, Bilge; 35330566
    Background: Direct oral anticoagulants (DOACs) have been used in acute pulmonary thromboembolism as an alternative to warfarin due to drug interactions, narrow therapeutic range, and necessary close International Normalized Ratio (INR) monitoring. Phase 3 study results have reported that these drugs are at least as effective as warfarin and beneficial in terms of bleeding; however, studies that present up-to-date life data are necessary. Aims: To evaluate the frequency of using DOACs, which are prescribed with a limited number of indications in our country, and real-life data results. Study Design: Cross-sectional study Methods: This cross-sectional survey collected the clinical data (history, current treatment, treatment duration, etc.) of patients with pulmonary thromboembolism and who applied to the physician for follow-up between October 15, 2019, and March 15, 2020. The researchers kept the patient records sequentially. Results: Data from 836 patients with acute pulmonary thromboembolism from 25 centers were collected, and DOAC was used in 320 (38.5%) of them. The most preferred DOAC was rivaroxaban (n = 294, 91.9%). DOAC was mostly preferred because it could not provide an effective INR level with warfarin (n=133, 41.6%). Bleeding was observed in 13 (4%) patients. Conclusion: The use of direct oral anticoagulants is becoming almost as widespread as conventional therapy. Real-life data results are important for their contribution to clinical practice.