Browsing by Author "Kocum, I. C."

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    Antenna-Type Radiofrequency Generator in Nanoparticle-Mediated Hyperthermia
    (2016) Nasseri, B.; Yilmaz, M.; Turk, M.; Kocum, I. C.; Piskin, E.
    Induction of hyperthermia using nanoparticles with specific magnetic, electrical, acoustic, optical or thermal properties is a potential alternative to conventional thermal ablation in cancer therapy. In this study, for the first time we employed an antenna-type radiofrequency (RF) generator as the energy source and as a proof of concept the effects of nanoparticles of varying structures and sizes, such as super-paramagnetic iron oxide nanoparticles (SPIONs), gold-coated superparamagnetic iron oxide nanoparticles (Au@SPIONs), spherical gold nanoparticles (AuNPs), and gold nanorods (AuNRs) on RF hyperthermia were examined to determine hyperthermia efficiency of the antenna-type RF generator. In preliminary experiments, RF was applied at varying powers to various nanoparticle solutions. In all cases, temperature rises due to exposure of RF radiation to nanoparticles were captured by using an infrared thermal camera. This procedure was applied to in vitro tests of fibroblast (L-929) and breast cancer (MCF-7) cell lines. Cell viability, apoptosis and necrosis were evaluated in both cell lines to comprehensively determine cell toxicity. Due to their particle size and chemical nature, SPIONs, in the case of highest RF power and nanoparticle concentration, resulted in the lowest cell viability and highest levels of apoptosis and necrosis.
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    Peculiarities of The Dielectric Response of The Silver-Modified-Zeolite Porous Microstructure
    (2016) Bunyatova, U.; Koc, S. Ozturk; Orbukh, V. I.; Eyvazova, G. M.; Agamaliev, Z. A.; Lebedeva, N. N.; Kocum, I. C.; Salamov, B. G.; Ozer, M.; J-5194-2019
    The aim of this study was to characterize electrical conductivity and dielectrical properties of the silver-exchanged zeolite-natural clinoptilolite from Western part of Turkey and Azerbaijan in the range of frequencies from 200 Hz to 1 MHz and at room temperature. For a better understanding the effect of concentration and content of silver in the nanoporous zeolite volume on the conductivity, a study of the dielectric properties of an un-modified and silver-modified zeolite plates with different amounts of Ag ions and Ag nanoparticles is performed. Un-modified and three different types of the silver ion-exchanged modified clinoptilolite plates were prepared. It was found, that with increasing silver concentration, resistance of zeolite plate monotonically decreases at the same time a capacitance is increases. It is suggested an explanation of the observed frequency dependence of the capacitance and resistance of zeolite plates on the silver concentrations may be explain on the basis of an electrode-dielectric interface gap model. At the same time, the observed phenomenon can be explained by considering the fact that with increasing content of silver the conductivity increases. These results show that Ag nanoparticles play significant role for performance improvement in plasma electronic devices with zeolite cathode. (C) 2016 Elsevier Ltd. All rights reserved.