Browsing by Author "Kiziltan, Gul"
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Item Assessment of Risk Factors of Obesity and Diet on Breast Cancer in Ankara, Turkey(2016) Kiziltan, Gul; Alim, Nural Erzurum; 28083060Objective: To determine the risk factors of obesity and diet on breast cancer in Ankara, Turkey. Methods: A case-controlled study was carried out on newly diagnosed 40 breast cancer patients [patient group (PC)] and 40 volunteer individuals [control group (CG)] with no diagnosis of cancer and history of cancer in the family with similar characteristics to the age and gender-matched patient group between March and July 2016. All the individuals were administered a questionnaire by face-to-face interview method. Results: The mean menarche age, age at first birth and menopause age were 13.0 +/- 1.17, 22.6 +/- 3.78 and 44.33 +/- 2.39 years in PG and 12.3 +/- 0.95, 21.6 +/- 2.99, 46.71 +/- 2.41 years in CG, respectively. The mean BMI values were determined as 28.1 +/- 6.75 kg/m(2) in PG and 30.1 +/- 6.18 kg/m(2) in CG (p>0.05). It was determined that intake of vitamin C and fiber decreases the risk of breast cancer. Also, eating quickly and smoking were risk factors for breast cancer (p<0.05). Conclusion: This study indicated that there are relationships between menarche age, menopause age, and age at first birth, eating quickly, smoking and breast cancer. Conversely, there are significant negative relationships between dietary fiber, vitamin C intake and breast cancer. As a result, it can be said that there is a link between breast cancer and lifestyle factors and a reduction in the risk of developing breast cancer can be achieved through changes in diet, one of the lifestyle factors.Item Association of the Relationship Between Nutritional Status and Certain Biochemical Parameters in Obese Children(2021) Ozcelik-Ersu, Dilek; Kiziltan, GulThe prevalence of childhood obesity is increasing globally. Adiposity is more concentrated in subcutaneous tissue in women and visceral fat tissue in men. Abdominal obesity is more commonly associated with metabolic diseases in men. The results showed that the mean BMIz scores of boys was higher than girls, but total body fat was lower than girls. Total body fat free mass, water and muscle mass were higher in boys than girls. It was determined that children aged 10-17 years consumed fatty and sugary snacks and sugary drinks at school. Food consumption containing the carbohydrate, fat, saturated fat and cholesterol were higher in boys than girls. As a result, it was thought that it would be more beneficial and reliable to use anthropometric methods showing body composition together with BMI zscore while evaluating body weight in adolescents. While nutritional counseling, it may be beneficial to consider that the energy and nutrient requirements of male adolescent individuals and their daily food consumption are higher than girls. When the results of the study are evaluated, we mention that it would be appropriate to evaluate girls more carefully in terms of iron deficiency anemia and diseases such as insulin resistance and diabetes.Item Challenges and needs of informal caregivers in elderly care: Qualitative research in four European countries, the TRACE project(2020) Akgun-Citak, Ebru; Attepe-Ozden, Seda; Kav, Sultan; Acar, Sema; Aksoydan, Emine; Altintas, Atahan; Aytar, Aydan; Baskici, Cigdem; Kiziltan, Gul; 0000-0003-0361-7498; 0000-0002-0484-4687; 31756568; V-9745-2019; ABD-7108-2020Background: Providing informal care may affects caregivers' life in different ways. Determining the needs of caregivers and supporting them can improve both the quality of life of the caregivers, as well as the elderly they take care of. Objective: To explore the experiences and needs of the informal caregivers in four countries. Design: Qualitative research method was used in the study. Methods: The qualitative data was collected through focus groups and individual interviews between December 2016-May 2017. In all countries interviews were conducted in the mother language of the informants. Informants of the qualitative research were adult people who take primary care of an individual with chronic diseases, aged 65 years or older. Data were collected from 72 informal caregivers from four European countries. Inductive content analysis was performed. Results: Informal caregivers identified 2 themes, 5 subthemes, 19 categories and 7 subtcategories. The themes highlighted two major issues: informal caregiver's challenges and needs related to the management of care of elderly and caregivers' personal needs. Conclusion: The important and charming results of the present study are, difficulties of managing caregiver's own life, and coping with emotions are common in four countries. Identifying challenges and needs of informal caregivers enable healthcare professionals to develop care strategies and plan interventions focused to support and help to reduce the burden of care for elderly with chronic diseases.Item Combined Therapy with Probiotic VSL#3 and Omega-3 Fatty Acids Attenuates Colonic Injury and Inflammation in Chronic DNBS-induced Colitis in Mice(2021) Ilktac, Havvanur Yoldas; Kiziltan, Gul; Lanpir, Asli Devrim; Ozansoy, Mehmet; Gunal, Mehmet Y.; Togay, Sine Ozmen; Keskin, Ilknur; Ozdemir, Ekrem M.; Kilic, UlkanInflammatory bowel disease (IBD) is a progressive chronic inflammatory disease affecting the gastrointestinal tract with a chronic relapsing and remitting disease course. While there are a number of therapeutic strategies available to treat IBD, a definitive treatment still hasn't been defined, leading to alternative treatment options including nutritional support. Herein, we planned to investigate the combined impact of probiotics and omega-3 (omega-3) fatty acids on inflammatory response and intestinal epithelium in chronic colitis induced by 2,4-Dinitrobenzenesulfonic acid (DNBS). Fifty BALB/c mice were randomly divided into five groups: non-colitis control, colitis with no treatment applied (control colitis), colitis treated with probiotics (VSL#3), colitis treated with omega-3, and colitis treated with both VSL#3 and omega-3. Colitis was induced by intrarectal administration of 2,4-Dinitrobenzenesulfonic acid (DNBS) in all groups but the non-colitis control group. Ten days after the DNBS period, phosphate-buffered saline (for both the non-colitis control and colitis control groups), VSL#3, omega-3, or VSL#3 + omega-3 treatments were administered intragastrically to their respective groups for 10 days. By analyzing the colonic expression of interleukin IL-6, IL-10, and IL-17A, and interferon gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) levels, results revealed that levels of IFN-gamma IL-17, and TNF-alpha were significantly higher in the control colitis group when compared with the other groups. The control colitis, colitis +VSL#3, and colitis + omega-3 groups exhibited higher scores of microscopic damage compared to the non-colitis control and colitis + VSL#3 + omega-3 groups. The closest histological image to the non-colitis control group was presented in the colitis + VSL#3 + omega-3 group. The findings indicate that the combined effect of probiotics and omega-3 fatty acids might have a protective effect against colon injury and inflammation by creating synergistic effects. However, more research is needed to understand the exact mechanism of this synergistic effect and to examine how this therapeutic approach can be used in inflammatory bowel diseases.Item Combined Therapy with Probiotic VSL#3 and Omega-3 Fatty Acids Attenuates Colonic Injury and Inflammation in Chronic DNBS-induced Colitis in Mice (vol 69, pg 135, 2021)(2022) Ilktac, Havvanur Yoldas; Kiziltan, Gul; Lanpir, Asli Devrim; Ozansoy, Mehmet; Gunal, Mehmet Y.; Togay, Sine Ozmen; Keskin, Ilknur; Ozdemir, Ekrem M.; Kilic, UlkanItem Effect of adherence to carbohydrate counting on metabolic control in children and adolescents with type 1 diabetes mellitus(2020) Bayram, Sinem; Kiziltan, Gul; Akin, Onur; 0000-0003-1569-7747; 32871653Purpose: Carbohydrate counting provides better glycemic control and flexibility than other food planning methods. Consistent adherence to such a complex method is difficult, especially for youth. However, studies that determine adherence to this method and whether it alters metabolic control are limited. The aim of the current study was to determine adherence to this method and investigate its effect on metabolic control, anthropometric measurements, insulin dose, and energy intake. Methods: In this prospective cross-sectional study, 53 children and adolescents with type 1 diabetes mellitus aged 2 to18 years and receiving intensive insulin therapy were trained and followed for 6 months. Demographics, anthropometrics, insulin requirements, hemoglobin A1c (HbA1c), fasting lipids, and food records at baseline and study conclusion were evaluated. At the end of the study patients were divided into adherer and nonadherer groups according to carbohydrate estimate deviations from standardized daily sample menus and calculations for accurate insulin doses. More than 10-g variation in daily consumed carbohydrate amount or failure to decide bolus insulin dose was defined as a nonadherer. Results: The mean HbA1c, low-density lipoprotein cholesterol, and body mass index standard deviation score changed after the carbohydrate counting training while the mean HbA1c between groups was significant (P<0.05). Total daily insulin doses increased, and the mean high-density lipoprotein cholesterol levels decreased in both groups. There were significant correlations between HbA1c and carbohydrate deviation scores as well as HbA1c and caregiver's education level. Conclusion: Since adherence to carbohydrate counting may affect metabolic control, health professionals should evaluate and monitor carbohydrate counting skills of caregivers and patients in order to improve efficiency.Item The Effect of Family Participation in Nutrition Education Intervention on the Nutritional Status of Preschool Age Children(2019) Aktac, Sule; Kiziltan, Gul; Avci, SuleymanTo evaluate the effectiveness of family participation in nutrition education intervention on the nutritional status of preschool age children, a 10-week nutrition education program was implemented in 74 children in a public kindergarten. Children were assigned to one of three groups, namely the family participation group (FPG), the education group (EG), and the control group (CG). Interventions included school-based nutrition education, family nutrition education documents and family-child take-home activities and monthly meetings with families in the FPG, school-based nutrition education in the EG, and no intervention in the CG. Anthropometric measurements and a 3-day food record and food group consumption assessment were completed before and after intervention. Intervention led to positive changes in food availability, offering and consumption patterns in FPG and EG, with greater changes in FPG, along with lower obesity prevalence (p < 0.05). Our results show that family participation in a preschool nutrition education program can increase the effectiveness of nutrition education.Item Effect of Nutrition Education on Diet Quality, Sustainable Nutrition and Eating Behaviors among University Students(2021) Yolcuoglu, Irem Zeynep; Kiziltan, Gul; 34330188Objective Nutrition information is provided by proper nutrition education and nutrition education programs have a direct impact on nutrition knowledge and behavior. This study aims to determine the effect of nutrition education on diet quality, sustainable nutrition and eating behavior. Design Cross-sectional survey. Participants The study was carried out on a total of 204 individuals, 21 males and 183 females, who were studying in the 3rd and 4th grades of Baskent University Faculty of Health Sciences. Main outcome measures Mean Adequacy Ratio (MAR) score calculated with the Nutrient Adequacy Ratio (NAR) was used to evaluate the diet quality. 'Sustainable and Healthy Eating Behaviors Scale' was applied to measure sustainable and healthy eating behaviors. Analysis A questionnaire including personal information and anthropometric measurements of the individuals and a 24-hour dietary recall was taken. Food consumption records were evaluated using the Nutrition Information System. In order to evaluate the quality of the diet, the Mean Adequacy Ratio (MAR) score calculated with the Nutrient Adequacy Ratio (NAR) was used. 'Sustainable and Healthy Eating Behaviors Scale' was applied to measure sustainable and healthy eating behaviors. SPSS 20.0 package program was applied to evaluate the data. Results In the study, 47.5% of the individuals were educated in Nutrition and Dietetics program and 52.5% were in other programs. The diet quality of 44.8% of the individuals studying in the Nutrition and Dietetics program and 56.4% of the individuals studying in the other programs were determined as 'good' according to the MAR levels classification. No significant difference was found in terms of MAR levels of individuals according to the departments they read (p > 0.05). The average score of the 'Healthy and Balanced Nutrition' factor in the scale of sustainable and healthy eating behaviors was higher in individuals who were studying in the Nutrition and Dietetics program. The average scores of 'Seasonal Food' and 'Low Fat' factor were found to be significantly higher in girls studying in the Nutrition and Dietetics program (p < 0.05). Conclusion It was determined that nutrition education is effective on sustainable and healthy eating behaviors. Considering the importance of nutrition education on the health of individuals and sustainable environment, it is of great importance in terms of public health to increase the awareness of the society on this issue.Item The effect of nutrition theraphy on oxidative stress, inflammation, glycemic control in type 2 diabetes patients(2019) Colak, Gozde Aritici; Kiziltan, GulAims: Type 2 diabetes mellitus is a metabolism disease which is seen frequently among adult population in Turkey. The aim of this study was to determine the medical nutrition theraphy effect on oxidative stress, inflammation, glycemic control in type 2 diabetes patients. Methods: An interventional study was carried on 35 type 2 diabetes ages between 20-65 years old at the Department of Endocrinology of Baskent University Istanbul Hospital in 2015. In 3 month period a personal nutrition theraphy was applied. Biochemical parameters, anthropometric measurements and body analysis were also determined. The three day food consumption and biochemical parameters were requested at the beginning and at the end of the study. Results: When the impact of the blood values of the new medical nutrition theraphy which the patients practiced during the first visit and the follow up visit were compared; it was seen that there was a significant decrease on fasting plasma glucose, fasting insulin, HbA1c, CRP, TG and MDA values (p<0.05). The mean diabetic age of the patients was 7.63 +/- 6.22 years. When diabetic age of the patients was increased, there was a positive correlation between the fasting plasma glucose and HbA1c values (p<0.05). Conclusions: Type 2 diabetes patients were evaluated 3 month of medical nutrition theraphy and it was seen that the personal medical nutritional theraphy contributed to providing glisemic control and decreasing oxidative stress and inflammation.Item The Effect of Probiotic and Omega-3 Supplements on Total Oxidant and Total Antioxidant Levels in Experimental Colitis(2021) IIlktac, Havvanur Yoldas; Kiziltan, Gul; Ozansoy, Mehmet; Kilic, Ulkan; Togay, Sine Ozmen; Keskin, Ilknur; Ozdemir, Ekrem Musa; Gunal, Mehmet YalcinObjective: Treatment of inflammatory bowel disease (IBD) usually involves medical therapy. For this reason, it is recommended to seek alternative treatment methods such as nutritional therapy. The aim of the study is to evaluate the effects of probiotics and omega-3 fatty acids on total oxidant and total antioxidant levels in an experimental colitis model. Methods: Mice were randomly divided into five groups (n= 10/group) as healthy group, colitis group, group treated with probiotics (VSL#3), group treated with omega-3 (w-3), and group treated with both probiotics and omega-3. To induce experimental colitis, 200 mg/kg dinitrobenzene sulfonic acid (DNBS) + 30% ethanol combination was rectally administered to anesthetized mice. Total oxidant (TOS) and total antioxidant (TAS) levels were measured at the tissue level. Results: Lower concentrations of TOS were observed in the probiotics groups (2.11 +/- 0.23 mmol H2O2 Eq/L), probiotics+omega-3 (2.56 +/- 1.18 mmol H2O2 Eq/L), and omega-3 (3.02 +/- 1.88 mmol H2O2 Eq/L) groups compared to the colitis group (3.11 +/- 0.91 mmol H2O2 Eq/L) (p>0.05). Higher TOS and TAS level were observed in the control colitis group compared to other groups; however, the differences were not statistically significant. Conclusion: Our findings showed that TAS and TOS levels were positively affected by the use of probiotic supplements in IBD. It was determined that using w-3 alone was ineffective in decreasing TOS levels. Studies with higher dosages and longer treatment periods are needed to better observe the effects of nutritional supplements on TOS and TAS parameters in inflammatory bowel diseases.Item Effect of weight loss diets on biochemical parameters and anthropometric measurements in prolactinoma patients(2019) Yesil, Esen; Kiziltan, Gul; Anil, Cuneyd; Ok, Mehtap Akcil; Bayraktar, Nilufer; AAZ-8170-2020Background: The aims of this study were to determine the effect of weight loss on biochemical parameters and anthropometric measurements in prolactinoma patients and to evaluate the effectiveness of weight loss diet along with medical treatment. Methods: Twenty-two patients with prolactinoma were divided into two groups and one of the groups was applied weight loss diet (diet group) while the other group was diet free (control group). Each participant was interviewed using a structured questionnaire. The biochemical parameters (fasting plasma glucose, fasting plasma insulin, prolactin, leptin, TSH, T4, cortisol, HbA1c, AST, ALT and blood lipids) of participants were analyzed and anthropometric measurements were taken. Results: There was a significant change in mean BMI after treatment in diet group (p=0.000). The mean level of serum prolactin decreased from 45.1 +/- 31.63 ng/dL at baseline to 12.6 +/- 8.19 ng/dL after three months in diet group (p=0.006). Despite there being no statistically significant difference between diet and control group in terms of baseline level of prolactin measurement (p=0.800), statistically significant difference between the two groups in terms of final level of prolactin measurement (p=0.027) was observed. There was a significant change in mean level of leptin after treatment in diet group (p=0.001). Conclusions: In addition to medical treatment, weight loss diets sped up the healing process for hyperprolactinemia and the reduction in body weight had positive effects on the metabolic profiles of prolactinoma patients.Item The Effects of Glucose and Fructose on Body Weight and Some Biochemical Parameters in Rats(2018) Koseler, Esra; Kiziltan, Gul; Turker, Perim Fatma; Saka, Mendane; Ok, Mehtap Akcil; Bacanli, Didem; Aydos, Tolga Resat; Bayraktar, Nilufer; Ozdemir, Handan; 0000-0002-4254-3711; 0000-0002-1832-9336; 0000-0002-7886-3688; AAZ-8170-2020; AAJ-7279-2020; Y-8758-2018Objective: Dietary fructose from added sugar as high fructose corn syrup may causes major risks in obesity, hyperlipidemia, cardiovascular diseases, hyperuricemia and fatty liver. The aim of this study was to investigate and compare the effects of high fructose and high glucose intake on body weight and some biochemical parameters in rats. Subject and methods: The study was conducted on adult, 32 Wistar albino male rats (300-350 g weeks) which fed with standard laboratory chow. In each group, 8 rats was selected randomly and which was be composed four groups. The rats in each group, in addition to standard meal, different amount of glucose and fructose containing solutions (10% and 30% glucose-fed group, 10% and 30% fructose-fed group) was given by oral gavage for 6 weeks. At baseline and after 6 weeks total cholesterol, VLDL-cholesterol, triglycerides, uric acid, AST and ALT as biochemical parameters and liver histopathological examination of rats were determined. Body weight of the rats was evaluated every week. Results: The 30% fructose group caused higher AST levels according to 10% glucose group, 30% glucose group and 10% fructose group. At the end of 6 weeks, the mean body weight in the fructose-fed groups was higher than the glucose-fed groups (p>0.05). No statistically significant difference between rat groups' portal inflammation rates were found and the moderate and severe ballooning were observed in 30% fructose rats (p<0.05). Conclusions: As a result, dietary fructose from added sugar as high fructose corn syrup may causes major metabolic disorders.Item Effects of Nutritional Knowledge of Informal Caregivers on Depression and Metabolic Outcomes of Hemodialysis Patients(2021) Kiziltan, Gul; Turker, Perim Fatma; Beyaz, Esra Koseler; Saka, Mendane; Sayin, Cihat Burak; 0000-0001-8287-6572; 34459351; J-3707-2015Chronic renal failure (CRF) makes significant changes in the life of patients and their families. A good family support has a positive effect on successful patients' adaptation to the treatment and compliance with dietary regimen. This study aimed to examine the effects of nutritional knowledge of informal caregivers on depression and metabolic outcomes of hemodialysis patients. This was a cross-sectional study conducted at Baskent University Hemodialysis Center with 116 hemodialysis patients and their informal caregivers. Findings revealed that the caregivers who were the couple of the patients had the highest nutritional knowledge level than the other caregivers (p < .05). The postgraduate caregivers were more likely to have high nutritional knowledge level than the others (p < .05). The inflammation marker of the patients was significantly lower in the group of caregivers with higher level (T3 group) of nutritional knowledge than the others (p < .05). The mean CES-D scores were also more likely to be low in T3 group than in the others (p < .05). These findings highlight that the nutritional knowledge of caregivers of hemodialysis patients may have an additional benefit on patients' nutritional management and metabolic outcomes.Item The Effects of Oral Nutritional Formula Enriched With Arginine, Omega-3 Fatty Acids And Nucleotides on Methotrexate-Induced Experimental Intestinal Mucositis(2018) Akyuz, Elvan Yilmaz; Akyuz, Cebrail; Kiziltan, Gul; Sehirli, Ahmet Ozer; Cetinel, SuleThe aim of this study to investigate the effect of an immunonutritional (IN) oral formula enriched with arginine, omega-3 fatty acids and nucleotides in methotrexate (MTX)-induced experimental intestinal mucositis model. In the study, 32 rats were divided into four groups consisting eight animals in each. Control group fed for 5 days with only saline with gavage, IN group fed for 5 days with an oral IN formula three times a day, MTX group with an intraperitoneal single dose MTX (20 mg/kg), followed by saline with gavage, MTX-IN group with a single dose of MTX, followed by an oral IN formula three times a day. The blood and jejunal tissue sample were collected and then the rats were sacrificed on the sixth day of the study. The level of TNF-alpha, IL-1 beta in serum, luminol, lusigenin, glutathione, myeloperoxidase, malondialdehyde and Na-K+ ATPase in the jejunal tissue samples were analyzed. Histopathological examination was performed in the jejunal tissue samples. In the MTX group, TNF-alpha, IL-1 beta levels in serum, and luminol, lusigenin, malondialdehyde levels, and myeloperoxidase activity in tissue samples were found significantly higher than the control group. Glutathione and Na-K+ ATPase levels were lower in the jejunal tissue of the MTX group compared to control group. However, the supplementation of IN with the MTX resulted in a significant increase in glutathione and Na-K+ ATPase levels. Severe epithelium loss and inflammatory cell increase were observed in the MTX group on histological examination, whereas these parameters were regressed in the MTX-IN group. Increasing in the mitosis rate of enterocytes and inflammatory cell density decreased with the IN. In conclusion, this study shows that chemotherapy has adverse effects on intestinal mucosa and the IN formula has a protective effect of on MTX-associated intestinal damage.Item Effects of reproductive and sociodemographic factors on obesity in Turkish women: a pilot study(2019) Bayram, Sinem; Koseler, Esra; Kiziltan, Gul; Ok, Mebtap Akcil; Yesil, Esen; Kose, Beril; Ozdemir, Merve; Muftuoglu, Selen; Saka, Mendane; Aksoydan, Emine; Tayfur, Muhittin; Turker, Perim Fatma; Ercan, Aydan; 0000-0003-1569-7747; 0000-0002-4254-3711; AAF-4491-2021; AAG-6763-2020Background and aim: Obesity has become a global epidemic. The current research aimed to determine sociodemographic and reproductive predictors of obesity among Turkish women. Materials and methods: Eligible subjects (n:833) were 40-64 years-old women living in Turkey. A questionnaire consisted of questions about sociodemographic and reproductive factors and the International Physical Activity Questionnaire were applied to participants by face to face interviews. Multivariate logistic regression examined the risk of being obese with a range of sociodemographic and reproductive factors. All analyses were performed with SPSS software (version 17.0; SPSS, Chicago, Ill., USA). Results: The mean BMI of women aged 51-64 years was 30.59 +/- 6.35 kg/m(2). After adjustments for all other variables, increased obesity risk remained significant in women who had two children, housewifes, minimum active ones, ex smokers and had less than high school education. For multiple regression analysis sociodemographic factors from the bivariate analyses were entered, controlling for menarch age, menopausal age, hormone RT, parity, number of stillbirth, abortion. There was significant association between family income, occupation, education and BMI. Conclusion. In summary these findings showed comparable patterns of association of sociodemographic and reproductive factors with obesity in Turkey. Specific healthy lifestyle counseling is important for decreasing obesity in childbearing age women.Item Is neck circumference measurement an indicator for abdominal obesity? A pilot study on Turkish Adults(2014) Saka, Mendane; Turker, Perim; Ercan, Aydan; Kiziltan, Gul; Bas, Murat; 25352874Background: Neck circumference (NC) measurement is one of the simple screening measurements which can be used as an index of upper body fat distribution to identify obesity. Objectives: The aim of this study was to determine the relationship between neck circumferences and obesity. Methods: A total 411 volunteer adults participated in this study (174 men, 237 women). A questionnaire which consisted of anthropometric measurements and demographic features was used. Patients with NC >= 37 cm for men and >= 34 cm for women require evaluation of overweight status. Results: The percentages of the men and women with BMI >= 25kg/m(2) were 55.2% and 27.0% respectively and with high neck circumferences were 85.1% and 38.8%, respectively. The percentages of the men and women with high waist circumference were 31.6% and 79.3%, respectively. In both gender there were positive significant correlations between neck circumference, body weight (men, r=0.576; women, r=0.702; p=0.000), waist circumferences (men, r=0.593; women r=0.667; p=0.000), hip circumferences (men, r=0.568; women, r=0.617; p=0.000) and BMI (men, r=0.587; women, r=0.688; p=0.000). Conclusions: This study indicates that NC was associated with body weight, BMI, waist and hip circumferences and waist/hip ratio for men and women. A significant association was found between NC and conventional overweight and obesity indexes. NC was associated with waist/hip ratio for men and women.Item Is training for informal caregivers and their older persons helpful? A systematic review(2019) Aksoydana, Emine; Aytar, Aydan; Blazeviciene, Aurelija; van Bruchem-Visser, Rozermarijn L.; Veskelyte, Alina; Mattace-Raso, Francesco; Acar, Sema; Altintas, Atahan; Akgun-Citak, Ebru; Attepe-Ozden, Seda; Baskici, Cigdem; Kava, Sultan; Kiziltan, Gul; 0000-0003-0361-7498; 30953963; ABD-7108-2020; AAI-6607-2020; V-9745-2019Background: The steady increase in the number of people suffering from chronic diseases and increasing life expectancy raises new demands on health care. At the same time, the need for informal caregivers is increasing. This study aims to perform a systematic review of the methodologies used to identify effect of different types of training on informal caregivers and their older persons. Methods: MEDLINE (PubMed), CINAHL and Ovid were searched from December 2016 and April 2017. The following keywords were used; "informal caregiver", "training" "elderly", older persons". Identified publications were screened by using the following inclusion criteria; systematic reviews, randomized controlled trials, prospective cohort and multicentre studies, English language full text journals, samples or interventions that included caregivers of older persons and published in last 10 years. Results: Twenty four studies (12 randomised control trials, 8 intervention studies and 4 systematic reviews) were included. Most of the randomized controlled trials involved both caregivers and elderly. Pretests and post-tests were used in intervention studies (5 out of the 8 studies). ICT-based, psychosocial interventions on family caregivers' education program for caregivers were applied. Caregivers following a supportive educative learning had a significantly better quality of life. Conclusions: The findings of this systematic review suggest that support interventions for caregivers can be effective in reducing caregivers' stress, with a consequent improvement of the quality of care. However, results are based on relatively small studies, reporting somewhat controversial findings supporting the need to perform further research in this field.Item Kitchen Safety in Hospitals Practices and Knowledge of Food Handlers in Istanbul, Turkey(2014) Ercan, Aydan; Kiziltan, Gul; 25207588This study was designed to identify the practices and knowledge of food handlers about workplace safety in hospital kitchens (four on-premises and eight off-premises) in Istanbul. A kitchen safety knowledge questionnaire was administered and a kitchen safety checklist was completed by dietitians. The mean total scores of the on-premise and off-premise hospital kitchens were 32.7 +/- 8.73 and 37.0 +/- 9.87, respectively. The mean scores for the items about machinery tools, electricity, gas, and fire were lower in off-premise than on-premise hospital kitchen workers. The kitchen safety knowledge questionnaire had five subsections; 43.7% of the food handlers achieved a perfect score. Significant differences were found in the knowledge of food handlers working in both settings about preventing slips and falls (p<.05). Significant relationships were found between marital status, education level, and kitchen safety knowledge of the food handlers (p<.05).Item The Relation Between Meal Frequency and Obesity in Adults(2018) Muftuoglu, Selen; Ozdemir, Merve; Saka, Mendane; Ok, Mehtap Akcil; Koseler, Esra; Bayram, Sinem; Yesil, Esen; Kose, Beril; Turker, Perim; Ercan, Aydan; Aksoydan, Emine; Tayfur, Muhittin; Kiziltan, Gul; 0000-0003-1569-7747; AAF-4491-2021; AAX-4714-2021; AAG-6763-2020; AAZ-8170-2020Objective: To determine the relation between meal frequency and obesity in adults. Methods: A cross-sectional study was done among 1829 volunteer (520 men, 1309 women) selected through a multi-stage stratified random sampling method during 2015/2016. A standardized, confidential data collection sheet was used. It included socio-demographic factors, dietary behaviors, anthropometric measurements and energy-macro and micronutrient intakes. Results: The median meal frequency of women and men were 4 and 3, respectively. Approximately 57% of men and 61% of women have skipped meals and 76.8% of them were skipped their lunch. In addition, the individuals whose BMI were under and over 25 kg/m(2) (72.4%, 78.3%, respectively) often skipped lunch. The meal frequency positively correlated with waist to hip ratio in women (p<0.05). Additionally, there were positively significant correlations between meal frequency and saturated fatty acids, fiber, vitamin A, vitamin C, calcium and iron intake (p<0.05). Conclusion: This study indicated that increased meal frequency may have a beneficial effect on micronutrients intakes and some anthropometric measurements among adults.Item The Relationship Between Dietary Intakes and Total Kidney Volume in Patients with Autosomal Dominant Polycystic Kidney Disease Dietary Intake and Polycystic Kidney Volume(2022) Sevim, Yonca; Cebeci, Egemen; Ozkan, Ozlem Persil; Savas, Yildiray; Ozturk, Savas; Kiziltan, GulAim: There is a need to understand autosomal dominant polycystic kidney disease (ADPKD) patients' dietary habits since dietary interventions may have potential effects on ADPKD. In this study, we aimed to analyze the relationship between dietary nutrient intake and total kidney volume (TKV).Methods: This cross-sectional study was conducted on 54 ADPKD patients recruited from the Nephrology outpatient clinic between June and July 2014. TKV was determined by magnetic-resonance imaging and general characteristics, biochemical and urinary parameters were determined. The nutrient intakes of patients were calculated using the three-day dietary records obtained on three consecutive days.Results: The total kidney-volume median was found to be 1407 mL. Patients' total dietary energy and protein intakes were 25.8 +/- 9.4 kcal/kg, 0.9 +/- 0.3 g/kg, respectively. The percentage of carbohydrates, protein, and fat in energy was 49 +/- 7%, 14 +/- 3%, 37 +/- 7%, respectively. The mean intakes of thiamin, riboflavin, B6, calcium, magnesium, and zinc were sufficient, the mean dietary potassium intake was insufficient; and sodium intake was excessive in both sexes. In females, there was a negative but weak correlation between dietary vitamin C intake and TKV. In males, a negative but weak correlation was found between TKV and dietary intake of fiber, water, vitamin B6, vitamin K, magnesium, and iron. Conclusions: Dietary micronutrient intake may affect TKV according to sex.