Browsing by Author "Karadag, Ayse Serap"
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Item Dramatic response to colchicine treatment in acne fulminans patients with cytological hemophagocytosis: A case series of 12 patients(2022) Durdu, Murat; Tehci, Tugba; Karadag, Ayse Serap; https://orcid.org/0000-0003-1247-3932; 36156836Acne fulminans is a severe form of acne with a sudden onset, rapid ulceration of the lesions, and some systemic symptoms, with or without systemic symptoms. These papulopustular lesions, whose pathogenesis is not fully understood, may exacerbate with systemic isotretinoin or may be a component of some autoinflammatory syndromes. It is recommended to control these sudden pustular attacks with systemic steroids or anti-inflammatory drugs. Here, in 12 patients with acne fulminans who developed exacerbation during systemic isotretinoin treatment and whose cytological examination revealed hemophagocytosis, colchicine treatment was started in addition to low-dose isotretinoin treatment, and a very good response was obtained to this treatment approach that did not contain systemic corticosteroids.Item Effect of Informative Seminars During National Acne Week On Participants' Knowledge About Acne in Turkey(2021) Ozden, Hatice Kaya; Gunduz, Kamer; Ozcan, Hamdi; Akturk, Aysun Sikar; Demir, Filiz Topaloglu; Akbulut, Tugba Ozkok; Karadag, Ayse SerapBackground and Design: To investigate the contribution of informative presentations about acne vulgaris and questionnaires administered before and after informative meetings on patients' awareness and consciousness. Materials and Methods: Participants were asked to fill out a 20-question survey before and after informative seminars in hospitals and secondary and high schools as part of National Acne Week. The level of statistical significance was set as p <= 0.05. Results: A total of 466 participants completed the survey before and after the seminar, and the mean age of the participants was 17.4 +/- 6.9. Before the seminar, 31.1% of participants thought that acne is originated from the liver, whereas this figure decreased to 16.7% after the seminar. In all, 47.6% of participants consulted doctors and 23.9% consulted social media to seek information about acne; however, after receiving training, 77% preferred to consult a doctor. Of the participants, 51.1% were expecting to see the results of acne treatment in 1 or 2 weeks, whereas 83.3% stated that the effects would be seen in 2 or 3 months after the seminar. When the participants' educational background was grouped as "secondary-high school-other," a statistically significant difference was obtained (p<0.05). Conclusion: Our study features both patients' misconceptions and their incorrect attitudes about acne, and their level of knowledge improved significantly as a result of educational seminars. The relative benefit derived from educational seminars was positively related to the participants' highest level of education.Item Granulomatous Annular Diseases(2023) Uzuncakmak, Tugba Kevser; Durdu, Murat; Karadag, Ayse Serap; 37467899Granulomatous skin disorders comprise a large group of diseases that are typically characterized by granuloma formation both in the skin and in many other tissues. Cutaneous lesions are usually seen as erythematous papules and plaques that may occasionally be arranged in an annular, ringlike con-figuration. The etiopathogenesis is unclear in most cases, and granuloma formation may be associated with various systemic, infectious, and metabolic disorders, foreign bodies, environmental antigens, or malignancies. Treatment options are dependent on the etiology, extent, and severity of the lesions. This review includes the clinical, histopathologic, and dermatoscopy findings, differentials, and treatment op-tions for noninfectious granulomatous annular skin disorders.(c) 2023 Elsevier Inc. All rights reserved.