Browsing by Author "Hur, Ender"

Filter results by typing the first few letters
Now showing 1 - 4 of 4
  • No Thumbnail Available
    Item
    A New Method to Predict Survival in Hemodialysis Patients Impedance Ratio
    (2017) Hur, Ender; Gokalp, Cenk; Kose, Sennur Budak; Duman, Elif; Magden, Kemal; Yildiz, Gursel; Zoka, Bilal; Sezer, Siren; Duman, Soner
  • No Thumbnail Available
    Item
    New Method to Predict Survival in Hemodialysis Patients Using the Impedance Ratio
    (2019) Hur, Ender; Gokalp, Cenk; Kose, Sennur; Duman, Elif; Magden, Kemal; Yildiz, Gursel; Toka, Bilal; Sezer, Siren; Duman, Soner
    Objective: Bioimpedance spectroscopy (BIS) can be used to determine hypervolemia and malnutrition in chronic hemodialysis (HD) patients. In this prospective observational study, we investigated the survival predictability of impedance ratio (IR) calculated by BIS in HD patients (Clinical Trials Gov Identifier: NCT01468363). Materials and Methods: A total of 430 chronic HD patients, out of 500 prevalent chronic HD patients from the city of Zonguldak who met the inclusion criteria, were included in the study. With a mean follow-up of 32.2 +/- 14.4 months, BIS was performed in all patients. The IR percentage (IR%) was calculated by dividing the resistance values using the 200 kHz and 5 kHz impulses. Student's t-test, Cox regression analysis, and Kaplan-Meier survival analysis were performed, and a p<0.05 was accepted as statistically significant. Results: The mean age of 430 patients was 59 +/- 15 (10-92) years, and 54% of patients were male. By the end of the study, 125 (29%) patients died. Diabetes mellitus was observed in 46% of patients. Sixty-seven percent of patients used erythropoietin, and 41% used diuretics. The mean systolic blood pressure of patients before the dyalisis was 133 +/- 26 mmHg, and diastolic blood pressure was 79 +/- 12 mmHg. The IR values ranged between 73.2% and 94.1%. A multi-regression analysis that used the IR and included diabetes mellitus, age, gender, and albumin and hemoglobin levels showed that the mortality risk increased 16% (p<0.001). Evaluation using the quartiles showed decreased survival. Survival in the first quartile group was 42.8 months compared to 30.6 months in the last quartile group. Conclusion: The IR calculated using BIS data is a useful tool that can be employed to predict the survival in chronic HD patients. An early awareness of this increased mortality risk is important in terms of a close follow-up and appropriate treatment of these patients.
  • No Thumbnail Available
    Item
    The Relationship Between Bioimpedance-Measured Volume and Nutritional Parameters and Mortality in Hemodialysis Patients
    (2017) Hur, Ender; Kose, Sennur Budak; Magden, Kemal; Yildiz, Gursel; Soyaltin, Utku; Toka, Bilal; Turan, Naki; Celikors, Saadet; Altundal, Bunyamin; Tunc, Ali; Yilmaz, Adil; Sivri, Ahmet; Sezer, Siren; Duman, Soner
    OBJECTIVE: Hypervolemia and malnutrition are often undiagnosed risk factors for hemodialysis (HD). Our aim was to investigate the long-term effects of hypervolemia and malnutrition evaluated by bioimpedance spectroscopy (BIS) on survival. (Clinical Trials.Gov Identifier:NCT01468363). MATERIAL and METHODS: A total of 431 Prevalent HD patients were followed for 32.2+/-14.4 months. The patients underwent BIS measurement, a medical history was obtained, and routine tests were analyzed at the baseline and at the end of the study. Hospitalizations and complications of HD were recorded. RESULTS: The mean age was 59.4+/-14.6 (10-92) years with a total of 431 (53.6% males) patients of which 125 died. The percentage of diabetics was 47%, erythropoietin use 67%, and diuretic use 40%. Predialysis systolic blood pressure (BP) was 133.4+/-n 25.8 and diastolic BP 79.2+/-12.4 mm Hg. The rate of diabetes, and the number of hospitalizations and blood transfusions were higher in the patients who died. Diastolic BP as a clinical hypervolemia finding, BIS hypervolemia indicator of over hydration (OH), and extracellular water (ECW) were all increased, and fat tissue index as a malnutrition finding was decreased in patients who died. There were significant rates of anemia and hypoalbuminemia in this group as well. The cumulative survival was lower in hypervolemic patients as assessed by relative hydration status OH/ECW. CONCLUSION: Hypervolemia and malnutrition are the long-term mortality indicators in hemodialysis. Early diagnosis and treatment is important. Clinical findings may not be sufficient and laboratory and BIS methods can be used for diagnosis.
  • No Thumbnail Available
    Item
    SCREENING THE FABRY DISEASE IN HEMODIALYSIS POPULATION: A MULTI-CENTERED STUDY
    (2019) Dinckal, Cigdem; Hur, Ender; Akin, Davut; Emekdas, Baris; Saglam, Funda; Gun, Yelda; Ozkan, Oguzcan; Mercan, Emine; Taskin, Huseyin; Yayar, Ozlem; Yildiz, Gursel; Kulah, Eyup; Sezer, Siren; Duman, Soner