Browsing by Author "Haciyev, Ceyhun"

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    Obsessive-Compulsive Disorder From Embodied Cognition Perspective
    (2022) Kocak, Orhan Murat; Kayipmaz, Selvi; Kutluturk Uney, Pelin; Haciyev, Ceyhun; https://orcid.org/0000-0002-7984-2440; AAK-3227-2021
    Obsessive Compulsive Disorder (OCD) is characterized by problems of control over behavior and cognition. Although almost all of the studies on pathogenesis of OCD point out fronto-striatal dysfunction, it is still not possible to reveal mechanisms to explain the entire clinical course of OCD through these circuits. A more holistic explanation can be given through the Embodied Cognition (EC) perspective, which suggests that the alteration/dysfunction of low-level sensory-motor process may appear as a multifarious extent of dysfunction of high-level cognitive processes. Fronto-striatal circuits play fundamental role in behavioral control. These circuits also have a central role for the feed-forward motor control (FFMC). In FFMC, the internal model of movement is driven by efference copies as templates for motor behavior, without being adjusted by sensory information. If impairment of low-level sensory-motor processing is crucial to occurrence of compulsions, one possible hypothesis about this impairment is the problem which emerges from occurrence of efference copy in FFMC. On the other hand, the efference copy has also pivotal role for subject's feeling of the agency of an action. Therefore, there may be role of failure in reproduction of the efference copy in the background of subjects' experience of losing control on compulsive behaviors. In this paper, we will discuss how the EC perspective which can be one of the biological bases of computationalism, which brings neuroscientific explanations on the functioning of nervous system to a more symbolic perspective, may contribute to our understanding of etiopathogenesis of OCD. In this perspective, our method will be to integrate the theoretical basis provided by EC perspective to the current models for OCD, rather than falsifying them.