Browsing by Author "Gurbuz, Zafer Gokhan"

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    Comparison of Ho:Yag laser and pneumatic lithotripsy combined with transurethral prostatectomy in high burden bladder stones with benign prostatic hyperplasia
    (2016) Goren, Mehemet Resit; Ercil, Hakan; Altunkol, Adem; Alma, Ergun; Sener, Nevzat Can; Kuyucu, Faruk; Karakoyunlu, Ahmet Nihat; Vuruskan, Ediz; Ortoglu, Ferhat; Gurbuz, Zafer Gokhan; 0000-0002-2001-1386; 25937584; 2-s2.0-84928795122; Y-6143-2019
    Objectives: To compare the efficacy and reliability of Ho:YAG laser lithotripsy (FILL) and pneumatic lithotripsy (PL) in the treatment of bladder stones in patients with benign prostatic hyperplasia and stones >= 20 mm who were transurethrally treated in the same surgical session. Methods: We studied the data of patients with benign prostatic hyperplasia and >= 20 mm bladder stones who were treated with transurethral resection of the prostate and cystolithotripsy in the same session, obtained between January 2010 and February 2014 from three urology clinics. All patients underwent bipolar plasmakinetic (PK) transurethral resection of the prostate. For treatment of the bladder stone, either HLL or PL was applied. A total of 62 patients were divided into two groups: PK-PL (Group 1, n = 29) and PK-HLL (Group 2, n = 33). The data of both groups were analyzed for stone dimensions, stone fragmentation time, total operating time, hospitalization duration, prostate dimensions, success rates, and complications. Results: Group 1 included 29 patients with a mean age of 70 +/- 7.6 (range, 57-85) years, whereas Group 2 included 33 patients with a mean age of 67.5 +/- 10.5 (range, 45-84) years. In Group 1, five patients had mucosa injury, one patient had residual stone, and one patient had bladder perforation. In Group 2, three patients had mucosa injury, three patients had postoperative fever, and one patient had residual stone. Total operation time and stone fragmentation time were significantly lower in Group 2(p < 0.05). The remaining analyzed data were similar (p > 0.05). Conclusion: PK-HLL using a single shaft without the need for repeated access has the advantages of shorter fragmentation and operatidn time. Copyright (C) 2015, Asian Surgical Association. Published by Elsevier Taiwan LLC. All rights reserved.
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    Relationship Between Plasma Melatonin Levels and The Efficacy of Selective Serotonin Reuptake Inhibitors Treatment on Premature Ejaculation
    (2014) Kirecci, Sinan Levent; Simsek, Abdulmuttalip; Gurbuz, Zafer Gokhan; Mimaroglu, Saban; Yuksel, Alpaslan; Vural, Pervin; Degirmencioglu, Suzan; 24712716; JTT-5991-2023
    Objectives: To examine the relationship between premature ejaculation and plasma melatonin levels, and assess the efficacy of selective serotonin reuptake inhibitors in treating premature ejaculation. Methods: A total of 60 men with lifelong premature ejaculation and 40 healthy male controls were included in the present study. For each participant, a medical history was obtained, a physical examination was carried out, and intravaginal ejaculation latency time and melatonin levels were measured. Premature ejaculation patients were randomly categorized into three treatment groups: group 1 received fluoxetine (20 mg/day), group 2 received paroxetine (20 mg/day) and group 3 received sertraline (50 mg/day). Results: The mean baseline plasma melatonin levels in men with premature ejaculation were significantly lower than in the healthy controls (5.34 vs 14.84 pg/mL). After 4 weeks of treatment, the mean intravaginal ejaculation latency time scores for all of the premature ejaculation treatment groups showed a significant improvement from the baseline values. The plasma melatonin levels were also significantly increased (P < 0.05) from baseline (5.34 pg/mL) to 9.50 pg/mL, 10.24 pg/mL or 13.30 pg/mL for groups 1, 2 and 3, respectively. Conclusions: Our findings show that premature ejaculation is associated with decreased plasma melatonin levels. After treatment with selective serotonin reuptake inhibitors, an increased plasma melatonin level can retard ejaculation, presumably by both central and peripheral mechanisms. This is the first study to evaluate the possible role of serotoninergic interactions on the melatoninergic system in premature ejaculation.
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    Response to Editorial Comments to Relationship Between Plasma Melatonin Levels and The Efficacy of Selective Serotonin Reuptake Inhibitors Treatment on Premature Ejaculation
    (2014) Kirecci, Sinan Levent; Simsek, Abdulmuttalip; Gurbuz, Zafer Gokhan; Mimaroglu, Saban; Yuksel, Alpaslan; Vural, Pervin; Degirmencioglu, Sevgin; 24824946; JTT-5991-2023