Browsing by Author "Gulsun, S."

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    Healthcare-Associated Gram-Negative Bloodstream Infections: Antibiotic Resistance and Predictors Of Mortality
    (2016) Ergonul, O.; Aydin, M.; Azap, A.; Basaran, S.; Tekin, S.; Kaya, S.; Gulsun, S.; Yoruk, G.; Kursun, E.; Yesilkaya, A.; Simsek, F.; Yilmaz, E.; Bilgin, H.; Hatipoglu, C.; Cabadak, H.; Tezer, Y.; Togan, T.; Karaoglan, I.; Inan, A.; Engin, A.; Aliskan, H. E.; Yavuz, S. S.; Erdinc, S.; Mulazimoglu, L.; Azap, O.; Can, F.; Akalin, H.; Timurkaynak, F.; https://orcid.org/0000-0003-4044-9366; https://orcid.org/0000-0001-9060-3195; 27717604; HLX-0937-2023; AAE-2282-2021
    This article describes the prevalence of antibiotic resistance and predictors of mortality for healthcare-associated (HA) Gram-negative bloodstream infections (GN-BSI). In total, 831 cases of HA GN-BSI from 17 intensive care units in different centres in Turkey were included; the all-cause mortality rate was 44%. Carbapenem resistance in Klebsiella pneumoniae was 38%, and the colistin resistance rate was 6%. Multi-variate analysis showed that age > 70 years [odds ratio (OR) 2, 95% confidence interval (CI) 1.22-3.51], central venous catheter use (OR 2.1, 95% CI 1.09-4.07), ventilator- associated pneumonia (OR 1.9, 95% CI 1.1-3.16), carbapenem resistance (OR 1.8, 95% CI 1.11-2.95) and APACHE II score (OR 1.1, 95% CI 1.07-1.13) were significantly associated with mortality. (C) 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.