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Browsing by Author "Gulsahi, Ayse"

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    Accuracy of high-resolution ultrasound (US) for gingival soft tissue thickness mesurement in edentulous patients prior to implant placement
    (2021) Sonmez, Gul; Kamburoglu, Kivanc; Gulsahi, Ayse; 33201732
    Objectives: To evaluate and compare the accuracy of high-resolution ultrasound (US) with two different cone beam CT (CBCT) units and clinical assessment for measuring gingival soft tissue thickness in edentulous patients prior to implant placement. Methods and materials: The study consisted of 40 maxillary implant sites of 40 healthy patients (20 females, 20 males; mean age, 47.88 years). We prospectively evaluated labial/buccal gingival thickness in 40 implant regions (16 anterior and 24 posterior) by using limited field of view (FOV) CBCT images and US images in comparison to gold standard transgingival probing measurements. One-way analysis of variance (ANOVA) was used to compare mean measurements obtained from CBCT (Morita and Planmeca), US, and transgingival probing. Interclass correlation coefficient (ICC) estimates were calculated based on means with two-way mixed and absolute-agreement model. Bland Altman plot was used to describe agreement between clinical vs US and CBCT measurements by constructing limits of agreement. Statistical significance was set at p < 0.05. Results: There was no significant difference between methods used according to mean gingival thickness measurements obtained from the top (p = 0.519) and bottom (p = 0.346) of the alveolar process. US and CBCT measurements highly correlated with clinical measurements for both top and bottom alveolar process gingival thickness (p < 0.001). Distribution of differences between clinical measurements and both CBCT measurements showed statistically significant differences according to 0 (p < 0.05). Distribution of differences between clinical measurements and US measurements did not show statistically significant difference (p > 0.05). Conclusion: High-resolution US provided accurate information for the measurement of gingival soft tissue thickness in edentulous patients prior to implant placement.
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    Accuracy of The Third Molar Index for Assessing the Legal Majority of 18 Years in Turkish Population
    (2016) Gulsahi, Ayse; De Luca, Stefano; Cehreli, S. Burcak; Tirali, R. Ebru; Cameriere, Roberto; https://orcid.org/0000-0001-6487-3984; 27344224; AAD-6138-2021; HZK-4947-2023
    In the last few years, forced and unregistered childmarriage has widely increased into Turkey. The aim of this study was to test the accuracy of cut-off value of 0.08 by measurement of third molar index (I-3M) in assessing legal adult age of 18 years. Digital panoramic images of 293 Turkish children and young adults (65 girls and 128 boys), aged between 14 and 22 years, were analysed. Age distribution gradually decreases as I-3M increases in both girls and boys. For girls, the sensitivity was 85.9% (95% CI 77.1-92.8%) and specificity was 100%. The proportion of correctly classified individuals was 92.7%. For boys, the sensitivity was 94.6% (95% CI 88.1-99.8%) and specificity was 100%. The proportion of correctly classified individuals was 97.6%. The cut-off value of 0.08 is a useful method to assess if a subject is older than 18 years of age or not. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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    Age estimation in Turkish children and young adolescents using fourth cervical vertebra
    (2020) Gulsahi, Ayse; Cehreli, Sevi Burcak; Galic, Ivan; Ferrante, Luigi; Cameriere, Roberto; 31915966
    This study aimed to test radiographic projections of the posterior and anterior sides of the C4 vertebral body for age estimation in a cross-sectional sample of Turkish children and adolescents from the Baskent University Faculty of Dentistry. A sample of 232 x-rays from individuals aged between 5 and 15 years (101 boys and 131 girls) was analysed to investigate the correlation of age and changes in the projection ratio of the anterior and posterior sides of the body of the fourth cervical vertebra (Vba) in lateral cephalograms. The Normal Bayesian Calibration (NBC) model for age estimation was used to assess the relationship between Vba and age. The intra-observer repeatability and inter-observer agreement were 0.95 and 0.94, respectively. Age distribution gradually increased as Vba increased up to 14 years in both sexes. The difference between chronological and estimated ages did not increase with the increase in age. Calibration distributions of the dataset by the evaluation of Vba suggested mean absolute errors (MAEs) of 0.879 years and 0.906 years (mean interquartile ranges (MIQRs) 1.290 and 1.435 years)) in boys and girls, respectively. The biases of the estimates (beta(ERR)) were 0.013 and 0.027 for boys and girls, respectively. In conclusion, the NBC method on Vba variable appears to be suitable for age estimation in Turkish children and adolescents.
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    Age of Majority Assessment in Dutch Individuals Based on Cameriere's Third Molar Maturity Index
    (2018) Dogru, Hatice Boyacioglu; Gulsahi, Ayse; Cehreli, Sevi Burcak; Galic, Ivan; van der Stelt, Paul; Cameriere, Roberto
    Radiological examination of the third molar is done in living individuals for estimation of chronological age, especially in the late adolescence. The aim of this study was to assess the application of Cameriere's third molar maturity index (I-3M) to determine whether an individual is 18 years or older (adult) or younger than 18 years (minor) in a sample of Dutch individuals. The sample consisted of panoramic images of 360 individuals aged between 14 and 22 years old. Three observers performed the measurements. Gender was not statistically significant in discriminating adults and minors. The highest value of the Youden index of the receiver operating curve analysis was for the value of I-3M < 0.08 in discriminating individuals as minor or adult. The specificity (Sp) and sensitivity (Se) results for females were 96.3% and 72.7% respectively. The Sp and Se for males were 95.0% and 84.0% respectively. The probabilities of correctly classified individuals were 83.3% and 88.9%, and Bayes post-test probability was 96.3% and 95.7% in females and males respectively. Obtained results showed that the specific cut-off point of I-3M < 0.08 may be a useful and reliable method for adult age assessment in a Dutch population. (c) 2017 Elsevier B.V. All rights reserved.
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    Change in Periapical Lesion and Adjacent Mucosal Thickening Dimensions One Year after Endodontic Treatment: Volumetric Cone-beam Computed Tomography Assessment
    (2017) Kamburoglu, Kivanc; Yilmaz, Funda; Gulsahi, Kamran; Gulen, Orhan; Gulsahi, Ayse; https://orcid.org/0000-0003-3510-7265; 28132708; AAX-5565-2021
    Introduction: Changes in periapical lesion dimensions along with mucosal thickening after endodontic treatment have not been studied yet. Therefo1e, the objectives of this study were (1) to obtain linear and volumetric measurements of lesion dimensions in maxillary first molars with periapical pathology and (2) to measure maxillary sinus mucosal thickening in the vicinity of periapical lesions before and 1 year after endodontic treatment by using cone-beam computed tomography (CBCT). Methods: Twenty-one maxillary first molar teeth of 21 patients (14 female and 7 male) with periapical lesion that had local mucosal thickening in the vicinity of the periapical lesion were endodontically treated. A total of 21 maxillary first molar roots (8 mesiobuccal roots, 6 distobuccal roots, and 7 palatal roots), each one from different patients, was included. Pretreatment and 1-year post-treatment CBCT images of each tooth were obtained by using Kodak CS 9300 3D CBCT unit. Width, height, surface area, and volume measurements of periapical lesions and mucosal thickening of the maxillary sinus mucosa in the vicinity of the periapical lesion were measured before and 1 year after endodontic treatment. General linear model (analysis of variance) was used for the comparisons between measurements, and significance was set at P <.05. Regression analysis was also used to test the correlation between different measurements. Results: We found statistically significant differences between mean pretreatment and mean post-treatment measurements conducted by using CBCT images (width, P =.002; height, P <.001; maximum mucosal thickening, P <.001; medium mucosal thickening, P <.001; minimum mucosal thickening, P <.001; surface area, P =.032; and volume, P =.034). Considering gender, age, and root type variables, no significant differences were found for all the measurements conducted (P >.05). There were 36%, 41%, 53%, 54%, 53%, 73%, and 75% mean reductions in lesion width, lesion height, maximum sinus mucosal thickness, medium sinus mucosal thickness, minimum sinus mucosal thickness, lesion surface area, and lesion volume, respectively, before and 1 year after endodontic treatment. Regression analysis of pretreatment lesion volume versus percentage of post-treatment lesion volume change revealed a low regression coefficient (R2 = 16.7%, P >.05), showing a weak linear relationship. Conclusions: CBCT assessment of changes in periapical lesion and mucosal thickening dimensions may reveal useful information regarding endodontic treatment success.
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    Comparison of mandibular index values determined from standard panoramic versus cone beam computed tomography reconstructed images
    (2019) Secgin, Cansu Koseoglu; Gulsahi, Ayse; Yavuz, Yasemin; Kamburoglu, Kivanc; 30497908
    Objective. The aim of this study was to compare mandibular index values, including the mandibular cortical index (MCI), mental index (MI), and panoramic mandibular index (PMI), determined on the basis of cone beam computed tomography (CBCT) and panoramic reconstructed (PR) images. Study Design. PR and CBCT images of 182 patients were retrospectively analyzed. Cross-sectional (CS) and PR images were obtained from CBCT data. The MCI, MI, and PMI were assessed on CS, PR, and panoramic images and evaluated for intra- and interobserver agreements by kappa-value or intraclass correlation coefficient (ICC) analysis. Agreement among measurement methods was assessed by using the Bland-Altman method, with CS images as the gold standard for linear measurements. Results. Measurements from PR and CS images agreed with those from panoramic images in 66.7% and 53.8% of C3 classifications of MCI (porous cortices forming many endosteal residues), respectively. Panoramic and CBCT images exhibited good agreement in MI findings (ICC 0.91) and moderate (PR and panoramic images: ICC 0.79) to good (CS and panoramic images: ICC 0.87) agreement in PMI findings. Conclusions. Because of the overlapping of buccal and lingual cortices, panoramic images are especially inadequate for determining the C3 category of MCI. However, CS images obtained from available CBCT data provide better visibility compared with panoramic images and, therefore, can be used for evaluating mandibular indices.
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    Dental Anxiety and Fear: Relationship with Oral Health Behavior in a Turkish Population
    (2014) Yozugullu, Bulem; Gulsahi, Ayse; Celik, Cigdem; Bulut, Sule
    The aim of this study was to assess fear and anxiety in dental patients. Five hundred patients were evaluated using the Modified Dental Anxiety Scale and the Dental Fear Scale, along with a questionnaire. Oral health status was assessed using the Decayed, Missing, and Filled Teeth (DMFT)/Decayed, Missing, and Filled Surfaces (DMFS) index. Statistic al analysis was performed (P <.05). Sex significantly affected dental anxiety (P <.05), and sex, marital status, having children, and time elapsed since last visit to clinician affected dental fear (P <.05). DMFT/DMFS scores were not related to dental anxiety or fear (P >.05). Female sex alone was a significant predictor of dental anxiety; female sex, adulthood, marriage, having children, and time passed since last visit to a clinician are significant predictors of fear.
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    Dental Anxiety and Fear: Relationship with Oral Health Behavior in a Turkish Population
    (2014) Yozugullu, Bulem; Gulsahi, Ayse; Celik, Cigdem; Bulut, Sule; https://orcid.org/0000-0002-5936-0196; 24392477; AAA-1576-2021; AAC-5448-2020
    The aim of this study was to assess fear and anxiety in dental patients. Five hundred patients were evaluated using the Modified Dental Anxiety Scale and the Dental Fear Scale, along with a questionnaire. Oral health status was assessed using the Decayed, Missing, and Filled Teeth (DMFT)/Decayed, Missing, and Filled Surfaces (DMFS) index. Statistic al analysis was performed (P <.05). Sex significantly affected dental anxiety (P <.05), and sex, marital status, having children, and time elapsed since last visit to clinician affected dental fear (P <.05). DMFT/DMFS scores were not related to dental anxiety or fear (P >.05). Female sex alone was a significant predictor of dental anxiety; female sex, adulthood, marriage, having children, and time passed since last visit to a clinician are significant predictors of fear.
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    Does Radiopacity of Restorative Materials Change with Aging?
    (2017) Tuncer, Duygu; Gulsahi, Ayse; Cehreli, Sevi Burcak; Arhun, Neslihan; AAD-6138-2021; R-2536-2019
    Background: Dental materials should be radiopaque enough to be identified from enamel and dentin and enable the detection of secondary caries, marginal defects. The aim was to evaluate the radiopacity of restorative materials after 6 months of aging in distilled water. Material and Methods: Twenty-two restorative materials were used and the radiopacity them were first evaluated after setting and after 6-months of storage in distilled water. Human primary and permanent tooth slices were also used in the study. Restorative material specimens were prepared by using Teflon molds. Twelve specimens were prepared for each material group. All specimens were exposed together with an aluminum stepwedge using a phosphor plate. The analysis was made with Digora system. Results: Filtek-Silorane, Aelite-LSPosterior, Theracal-LC, Biodentine, Ionofil-U, Vitrebond and GCP-Glass-Seal exhibited lower radiopacity values at the initial setting and after 6-months of aging with respect to permanent enamel. When compared with deciduous enamel, Filtek-Z550, Charisma, Riva-Light Cure and Equia-Fil exhibited lower radiopacity values at both readings. Spectrum-TPH, Filtek-Ultimate, Clearfil-Majesty Flow, Sultan-Versa, IRM and Adhesor exhibited statistically significant higher values of radiopacity at the 6-month evaluation. Conclusion: The radiopacity of restorative materials is dependent on the material type exerting different radiopacity values after 6-months.
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    EVALUATION OF DENTAL AND PERIODONTAL HEALTH OF RENAL TRANSPLANT AND HEMODIALYSIS PATIENTS
    (2020) Oduncuoglu, Bahar; Gulsahi, Ayse; Arhun, Neslihan; Colak, Turan; Haberal, Mehmet A.
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    Evaluation of maxillary trabecular microstructure as an indicator of implant stability by using 2 cone beam computed tomography systems and micro-computed tomography
    (2019) Kulah, Kivanc; Gulsahi, Ayse; Kamburoglu, Kivanc; Geneci, Ferhat; Ocak, Mert; Celik, H. Hamdi; Ozen, Tuncer; 30595501
    Objective. The aim of this study was to assess the trabecular microarchitecture of the maxilla by using cone beam computed tomography (CBCT) and micro-computed tomography (micro-CT) ex vivo. Study Design. Seventeen maxillary cadaver specimens were scanned by using micro-CT and CBCT devices. Samples were scanned with 2 CBCT devices at different voxel sizes (0.08, 0.125, and 0.160 mm for 3-D Accuitomo 170; 0.75 and 0.200 mm for Planmeca Promax 3-D Max). Morphometric parameters, such as bone volume/total volume (BV/TV) ratio, trabecular thickness (Tb.Th), trabecular separation (Tb.Sp), trabecular number (Tb.N), and degree of anisotropy (DA) were assessed by using CTAnalyzer software. Bland-Altman limits of agreement and intraclass correlation coefficient (ICC) were performed to evaluate agreement between CBCT and micro-CT in consideration of measured morphometric parameters. Statistical significance was set at P < .05. Results. The BV/TV, Tb.Th, Tb.Sp, and DA values were higher for CBCT images compared with micro-CT images, whereas the Tb. N value was lower with CBCT images than with micro-CT images. The BV/TV and DA parameters showed the highest agreement between CBCT and micro-CT devices (ICC = 0.421 for BV/TV and ICC = 0.439 for DA; P < .01). Conclusions. The BV/TV and DA parameters measured on CBCT obtained at the smallest voxel size were found to be useful for the assessment of maxillary trabecular microstructure.
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    External apical root resorption after nonextraction orthodontic treatment with labial vs. lingual fixed appliances
    (2019) Pamukcu, Hande; Polat-Ozsoy, Omur; Gulsahi, Ayse; Ozemre, Mehmet Ozgur; 31792608
    Objectives The aim of this retrospective study is to compare external apical root resorption (EARR) after labial and lingual fixed orthodontic treatment, as detected with panoramic radiographs. Materials and methods Sixty subjects were divided into two groups according to the treatment type: lingual (30 patients) and labial (30 patients) fixed orthodontic treatment. Panoramic radiographs which were obtained at the beginning of treatment (T0) and at the end of the treatment (T1) were evaluated. The maxillary and mandibular central and lateral incisors, as well as canine crown and root lengths were measured for T0 and T1. Crown to root ratios were used to determine EARR. Data were evaluated using analysis of variance and chi(2) analysis. Results In all, 5 patients (16.7%) in the lingual group and 7 patients (23.3%) in the labial group had a minimum of one tooth with severe EARR, while 9 patients (30%) in the lingual group and 14 patients (46.7%) in the labial group had no EARR. A total of 26 teeth (7.2%) in the lingual group and 34 teeth (9.4%) in the labial group developed severe EARR; however, 184 teeth (51.1%) in the lingual group and 202 teeth (56.1%) in the labial group did not reveal any EARR. No statistically significant difference was found for the resorption rates between the treatment groups (p> 0.05). Although not statistically significant, there was a higher percentage of severe EARR in the mandible within the labial group. Conclusions Both lingual and labial orthodontic techniques showed statistically similar root resorption rates. EARR is a multifactorial issue and individual predispositions must also be taken into consideration.
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    Factors That May Increase The Risk of External Apical Root Resorption During Orthodontic Treatment Retrospective Clinical Investigation
    (2024) Kaya, Burcak; Gulsahi, Ayse; Turkyilmaz, Gizem
    PurposeTo determine the correlation between external apical root resorption and malocclusion-related variables in patients treated with fixed orthodontic appliances.MethodsIn all, 103 patients aged 12-15 years and treated with edge-wise appliances either without extractions or with four premolar extractions were included in this retrospective cohort study. External apical root resorption was assessed in the pre- and posttreatment panoramic radiographs of these patients for incisors, canines, premolars, and first molars. A total of 2332 teeth were evaluated in 206 panoramic radiographs obtained from 103 patients. The gender of the patients, duration of orthodontic treatments, presence of premolar extractions, Angle classification, overbite, overjet and amount of crowding were assessed. Wilcoxon signed-rank test, Mann-Whitney U test, and Kruskal-Wallis test were used for statistical analysis of the data.ResultsStatistically significant (p < 0.001) root resorption occurred in all examined teeth during orthodontic treatment. The degree of root resorption observed in the premolars was significantly greater in premolar extraction cases than in nonextraction cases. Statistically significant negative correlations were found between the degree of root resorption of the maxillary lateral teeth and between the maxillary first premolar teeth and the amount of maxillary crowding.ConclusionsThe orthodontic treatment protocols and the amount of tooth movements achieved were shown to be dependent on the severity of dental malocclusions and they have an influence on the amount of external apical root resorption that occurs during the course of orthodontic treatment.
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    Osteoporosis and jawbones in women
    (2015) Gulsahi, Ayse; 26312225
    Osteoporosis is a major health problem affecting one in three women over the age of 50 and may not be detected until fractures occur. Since osteoporotic fractures are a health burden worldwide, identifying subjects with a high risk of osteoporosis and preventing osteoporosis-related mortality and morbidity are a very important health strategy. Women show an estrogen-related bone loss starting at menopause, predominantly occurring in trabecular bone. Diagnosis of osteoporosis is usually based on the bone mineral density measurement, but this is not a practical and economical technique for early detection. Therefore, investigators are interested in the possibility of detecting osteoporosis from the panoramic radiographs. Mandibular cortical bone undergoes resorptive activity in osteoporotic patients, leading to a decreased thickness and more porous inferior border. Therefore, studies have demonstrated the usefulness of cortical width and shape, determined from panoramic radiographs, in identifying elderly individuals with undetected osteoporosis, especially postmenopausal women. In conclusion, postmenopausal women with C3 category, Mental Index (MI) < 3 mm, and panoramic mandibular index (PMI) < 0.3 may be considered for further osteoporosis investigation.
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    Pre-eruptive Intracoronal Resorption of Permanent Dentition: A New Classification and a Multidisciplinary Study
    (2023) Yuksel, Halil Tolga; Turkmenoglu, Aysegul; Celikkol, Berk; Evirgen, Sehrazat; Gulsahi, Kamran; Gulsahi, Ayse; https://orcid.org/0000-0003-3510-7265; 36317538
    The aims of this study were to develop a new classification for pre-eruptive intracoronal resorption(PIR) with different resorption areas and sizes and to compare the new classification scores among observers from different specialities and professional experience. The PIR was evaluated according to the new classification by two dentomaxillofacial radiologists and two endodontists. Information regarding the patient's age, gender, systemic diseases, the number of PIR, the affected tooth area and the size of the PIR was recorded. The new classification system showed that PIR six and seven defects were the most detected. Regarding jaw regions, the highest reliability was seen in the maxillary central teeth between observers I and IV, and maxillary premolar-molar teeth between observers II and III. This study revealed that PIR can be found in both root and crown dentine. Professional experience and specialty and awareness of the PIR defect may affect the diagnosis.
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    Relationship Between Maxillary Sinus Pathologies and Maxillary Posterior Tooth Periapical Pathologies
    (2016) Kasikcioglu, Ahmet; Gulsahi, Ayse
    To determine the prevalence of odontogenic maxillary sinus pathologies and their relationship with periapical pathologies in the maxillary posterior teeth using cone-beam computed tomography (CBCT). Maxillary posterior CBCT scans of consecutive patients aged 20-77 years were evaluated retrospectively. Patients with at least one maxillary posterior tooth were included. Patients with edentulous maxillae or having one or more maxillary implants were excluded. Finally, 461 CBCT images were evaluated. Demographic data, such as age and sex, and pathologic findings of the right and left maxillary sinuses and adjacent teeth were recorded. Statistical analyses were performed using the Chi square test and binary logistic regression. The prevalence of right and left odontogenic maxillary sinusitis was 59.5 and 64 %, respectively. Maxillary sinus pathology was more common in males, and there was no relationship with age. Regarding the maxillary sinus pathology, 64 % had mucosal thickening, 19 % had partial opacification, 5 % had total opacification, and 12 % had polypoidal mucosal thickening. Right and left maxillary sinus pathologies were approximately twice as prevalent in patients with periapical pathology in at least one maxillary posterior tooth. Periapical pathologies in the right maxillary first molar and left maxillary first and second molars significantly increased the risk of maxillary sinus pathology with odds ratios of 2.53, 1.83, and 3.12, respectively. Odontogenic maxillary sinus pathologies were present in > 50 % of the study population. Periapical pathologies in the maxillary first and second molar teeth significantly increased maxillary sinus pathologies.
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    THE RELATIONSHIP BETWEEN SKELETAL AND MANDIBULAR/ALVEOLAR BONE QUALITY AFTER SOLID ORGAN TRANSPLANTATION
    (2020) Oduncuoglu, Bahar; Gulsahi, Ayse; Arhun, Neslihan; Colak, Turan; Haberal, Mehmet A.
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    Third Molar Maturity Index (I-3M) Assessment According to Different Geographical Zones: A Large Multi-Ethnic Study Sample
    (2022) Angelakopoulos, Nikolaos; De Luca, Stefano; Oliveira-Santos, Ines; Ribeiro, Isabella Lima Arrais; Bianchi, Ilenia; Balla, Sudheer B.; Kis, Hatice Cansu; Jimenez, Lourdes Gomez; Zolotenkova, Galina; Yusof, Mohd Yusmiaidil Putera; Selmanagic, Aida Hadzic; Pandey, Hemlata; Pereira, Palmela C.; da Nobrega, Johnys Berton Medeiros; Kalani, Hettiarachchi; Mieke, Sylvia M.; Kumagai, Akiko; Gulsahi, Ayse; Zelic, Ksenija; Marinkovic, Nemanja; Kelmendi, Jeta; Galic, Ivan; Vazquez, Israel Soriano; Spinas, Enrico; Velezmoro-Montes, Ymelda Wendy; Moukarzel, Maria; Toledo, Jorge Pinares; El-Bakary, Amal Abd El-Salam; Cameriere, Roberto; 36520207
    Identification of living undocumented individuals highlights the need for accurate, precise, and reproducible age estimation methods, especially in those cases involving minors. However, when their country of origin is unknown, or it can be only roughly estimated, it is extremely difficult to apply assessment policies, procedures, and practices that are accurate and child-sensitive. The main aim of this research is to optimize the correct classification of adults and minors by establishing new cut-off values for four different continents (Africa, America, Asia, and Europe). For this purpose, a vast sample of 10,701 orthopantomographs (OPTs) from four continents was evaluated. For determination and subsequent validation of the new third molar maturity index (I-3M) cut-off values by world regions, a cross-validation by holdout method was used and contingency tables (confusion matrices) were generated. The lower third molar maturity indexes, from both left and right side (I3ML and I3MR) and the combination of both sides (I3ML_I3MR) were calculated. The new cut-off values, that aim to differentiate between a minor and an adult, with more than 74.00% accuracy for all populations were as follows (I3ML; I3MR; I3ML_I3MR, respectively): Africa = (0.10; 0.10; 0.10), America = (0.10; 0.09; 0.09), Asia = (0.15; 0.17; 0.14), and Europe = (0.09; 0.09; 0.09). The higher sensitivity (Se) was detected for the I3ML for male African people (91%) and the higher specificity (Sp) of all the parameters (I3ML; I3MR; I3ML_I3MR) for Europeans both male and female (> 91%). The original cut-off value (0.08) is still useful, especially in discriminating individuals younger than 18 years old which is the goal of the forensic methods used for justice.
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    Use of Cone-Beam Computed Tomography in Diagnosis of An Otherwise Undetected Periapical Lesion in An Anomalous Tooth
    (2014) Gulsahi, Ayse; Ates, Ufuk; Tirali, Resmiye Ebru; Cehreli, Sevi Burcak; https://orcid.org/0000-0001-6487-3984; HGA-3970-2022; AAD-2907-2020; AAD-6138-2021
    Fusion is a developmental anomaly of dental hard tissues. Since dental fusion is characterized by irregular coronal morphology and a complex endodontic anatomy, endodontic therapy of such teeth may present a serious clinical challenge. Cone-beam computed tomography (CBCT) is a useful tool for the management of complex endodontic problems and dental anomalies. In the case presented here, a CBCT scan revealed morphological details as well as the severity of periapical infection that had not been visualized with conventional imaging techniques. The results obtained with detailed imaging led to a change in the treatment plan.
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    Volatile Sulphur Compound Levels and Related Factors in Patients with Chronic Renal Failure
    (2014) Gulsahi, Ayse; Evirgen, Sehrazat; Oztas, Bengi; Genc, Yasemin; Cetinel, Yasemin; 24923904
    Aims: To analyse specific volatile sulphur compound(VSC) levels in a group of chronic renal failure (CRF) patients and determine the relationship between these VSC levels and organoleptic measurements, blood urea nitrogen (BUN) levels, dental and periodontal conditions, salivary flow rate, and tongue coating scores. Materials and Methods: One examiner performed organoleptic and VSC measurements on fifty patients with CRF before and after haemodialysis (HD) and controls. DMFT and CPITN indexes, tongue coating scores, salivary flow rates were measured. Comparisons were performed using the Mann-Whitney U, Wilcoxon signed-ranks, and chi-square tests. Spearman correlation coefficient was used to analyse correlations. Results: Before HD, the mean dimethyl sulphide level was 1.04 +/- 1.20 in the CRF patients and 0.51 +/- 0.65 in controls, with a significant difference. The mean hydrogen sulphide, methyl mercaptan and dimethyl sulphide levels in CRF patients were 1.47 +/- 3.04, 1.03 +/- 1.85, and 1.04 +/- 1.20, respectively, before HD; and 0.53 +/- 1.65, 0.48 +/- 1.27, and 0.56 +/- 0.85, respectively, after HD; with the differences being significant. Methyl mercaptan levels increased with an increase in HD duration. Tongue coating and organoleptic measurements were significantly correlated with methyl mercaptan. Conclusions: Dimethyl sulphide is the main VSC in extraoral blood-borne halitosis; but methyl mercaptan may also contribute to this type of halitosis. A decreased salivary flow rate and an increased pH of the biofilm matrix may be a significant parameter for VSC levels in CRF patients.

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