Browsing by Author "Gulleroglu, Aykan"

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CLINICAL OUTCOMES OF INFLUENZA INFECTION AMONG SOLID ORGAN TRANSPLANT RECIPIENTS IN ICU
(2020) Gulleroglu, Aykan; Kandemir, Tunay; Yalcin, Tugba; Gedik, Ender; Zeyneloglu, Pinar; Haberal, Mehmet A.
Outcome of Patients Admitted to Intensive Care Units due to Influenza-Related Severe Acute Respiratory Illness in 2017-2018 Flu Season: A Multicenter Study from Turkey
(2020) Ortac Ersoy, Ebru; Er, Berrin; Ciftci, Fatma; Gulleroglu, Aykan; Suner, Kezban; Arpinar, Burcu; Aygencel, Gulbin; Bacakoglu, Feza; Akpinar, Serdar; Comert, Bilgin; Sungurtekin, Hulya; Altintas, Defne; Rollas, Kazim; Turan, Sema; Topeli, Arzu; 0000-0002-6091-9065; 33271560; AAJ-4188-2021
Background: Influenza can cause severe acute respiratory illness (SARI), which occurs as local outbreaks or seasonal epidemics with high intensive care unit (ICU) admission and mortality rates. Mortality is mainly due to SARI. Objective: The aim of this study was to evaluate the outcome of patients admitted to ICU due to influenza-related SARI in 2017-2018 flu season in Turkey. Methods: A retrospective multicenter study was conducted in 13 ICUs with a total of 216 beds from 6 cities in Turkey. All adult patients (over 18 years) admitted to the ICUs in 2017-2018 flu season (between September 1, 2017, and April 30, 2018) because of SARI and with a positive nasopharyngeal swab for influenza were included in the study. Results: A total of 123 cases were included in the study. The mean age of patients was 64.5 +/- 17.5 years, and 66 (53.7%) patients were older than 65 years. The ICU mortality was 33.9%, and hospital mortality was 35.6%. Invasive mechanical ventilation (IMV), acute kidney injury (AKI), hematologic malignancy, and >65 years of age were the factors affecting mortality in influenza. Conclusion: SARI due to influenza carries a high mortality rate, and IMV, AKI, presence of hematologic malignancy, and older age are independent risk factors for mortality.
Post-operative Respiratory Distress Due to Laryngeal Granuloma and Subglottic Stenosis in a Patient Undergoing Open Heart Surgery
(2021) Yazar, Cagla; Aitakhanova, Manat; Gulleroglu, Aykan; Firat, Aynur Camkiran; Zeyneloglu, Pinar; 0000-0002-3887-0314; 0000-0002-6091-9065; AAJ-4188-2021
The cause of impairment in respiratory functions after open heart surgery is multifactorial. A 67-year-old female patient admitted to the intensive care unit (ICU) was intubated after mitral valve replacement and tricuspid annuloplasty. She was extubated on the first post-operative (post-op) day. On post-op day 5, the patient was re-admitted to the ICU due to respiratory distress and tachypnea. Non-invasive mechanical ventilation (NIMV) support and dobutamine 5 mcg/kg/min were started. Prior to diagnosis of septic shock, tazocin 3x4.5 grams was administered. The patient was intubated on the post-op day 6 because of the increase in respiratory distress. She was extubated on the post-op day 7, and NIMV commenced. On the 8th post-op day, she was consulted to the ear, nose and throat (ENT) department because of sore throat. Widespread mucosal aphthous lesions were observed in the uvula, soft and hard palate, mandible inner mucosa and alveolar process. Galactomannan was detected positive in bronchoalveolar lavage and treatment with fluconozole started. On post-op day 15, the patient was discharged. That same night, she was admitted to the ICU again due to sudden respiratory distress and was placed on NIMV support, but the patient whose respiratory distress increased and was unconscious was intubated. The next day, direct laryngoscopy was performed by the ENT department under operating room conditions, and a 3x4 cm polypoid lesion was removed from the vocal cord level. However, after 2 days, the patient was re-examined by direct laryngoscopy, necrotic crusts were removed under the cricoid cartilage posteriorly in the subglottic region. The patient recovered from post-op respiratory distress, was extubated on the 18th post-op day and his support with NIMV continued. The patient was discharged on the 33rd post-op day. Laryngeal granuloma and subglottic strictures should be considered in patients with post-op respiratory distress, no matter how short the intubation period is.
SAPS III or APACHE IV: Which score to choose for acute trauma patients in intensive care unit?
(2019) Toker, Melike Korkmaz; Gulleroglu, Aykan; Karabay, Ayse Gul; Bıcer, Ilhan Guncey; Demiraran, Yavuz; 31135940
BACKGROUND: The aim of the present study was to evaluate the effectiveness of the Simplified Acute Physiology Score (SAPS) III and the Acute Physiology and Chronic Health Evaluation (APACHE) IV in the prediction of in-hospital mortality in surviving multi-trauma patients. METHODS: This study was conducted in the 13-bed intensive care unit (ICU) of a tertiary hospital. A retrospective review of multi-trauma patients whose care was managed in the ICU was performed. Data collection included details of age, gender, ICU admission, and outcome. APACHE IV and SAPS III scores, as well as the predicted mortality rate (PMR), were calculated using web-based calculators. RESULTS: Of the 90 patients 20% (n= 18) were female and 80% (n= 72) were male. The overall mortality rate was 25.6%. The mean APACHE IV, Acute Physiology Score (APS) and SAPS III score was 69.27 +/- 34.51, 66.42 +/- 33.72, and 26.36 +/- 27.14, respectively. The mean PMR according to the APACHE IV and the SAPS III was 26.36 +/- 27.14 and 17.07 +/- 24.88, respectively. The area under the curve result of receiver operating characteristic curve analysis was 0.87 for the APACHE IV and 0.93 for the SAPS III. CONCLUSION: The performance of the SAPS III was more sensitive and discriminative than the APACHE IV scoring system for multi-trauma ICU patients.