Browsing by Author "Gencoglu, Esra Arzu"

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Abdominopelvic Tumor Implants Detected with a Bone Scan in a Case of Borderline Ovarian Tumor
(2015) Gencoglu, Esra Arzu; Cinar, Alev; Aktas, Aysel; 0000-0002-3426-2987; 0000-0003-4631-1683; ABA-7670-2021; ABG-1864-2020
Diagnostic Significance of the Hepatic Parenchymal Retention Index as Determined by Hepatobiliary Scintigraphy in Liver Transplant Recipients
(2014) Gencoglu, Esra Arzu; Aktas, Ayse; Haberal, Mehmet; https://orcid.org/0000-0003-4631-1683; https://orcid.org/0000-0003-0149-2265; https://orcid.org/0000-0002-3462-7632; 24635801; ABG-1864-2020; AAI-8772-2021; AAJ-8097-2021
Objectives: The aim of this study was to evaluate the usefulness of the hepatic parenchymal retention index in the early diagnosis of parenchymal complications in liver transplant recipients as determined by hepatobiliary scintigraphy. Materials and Methods: This retrospective study reviewed 100 liver transplant recipients who had undergone orthotopic liver transplant. In all cases, hepatobiliary scintigraphy images recorded 7 to 10 days posttransplant were quantitatively reinterpreted according to hepatic parenchymal retention index. The hepatocyte extraction fraction value was also calculated. Scintigraphic findings as well as clinical, laboratory, and biopsy results were assessed. Results: Quantitative analysis showed normal hepatocyte extraction fraction value in all subjects. However, significant differences in hepatic parenchymal retention index were observed. Thus, subjects were divided into 3 groups: group 1 (n=75), normal; group 2 (n=15), severely elevated; group 3 (n=10), mildly-to-moderately elevated hepatic parenchymal retention index. Evaluation of histopathological, clinical, and laboratory findings showed normal grafts in all group 1 recipients, acute rejection in all group 2 recipients, and hepatocyte damage/intrahepatic cholestasis in all group 3 recipients. Conclusions: Based on these findings, we determined that hepatocyte extraction fraction value was not useful, whereas hepatic parenchymal retention index was beneficial for early and accurate diagnosis of parenchymal complications in liver transplant recipients.
The Efficacy of Low and High Dose 99mtc-MIBI Protocols for Intraoperative Identification of Hyperplastic Parathyroid Glands in Secondary Hyperparathyroidism
(2014) Gencoglu, Esra Arzu; Aktas, Ayse; https://orcid.org/0000-0003-4631-1683; https://orcid.org/0000-0003-0149-2265; 24703993; ABG-1864-2020; AAI-8772-2021
Objective: The aim of this study was to compare the efficacy of low- and high-dose Tc-99m-MIBI protocols for intraoperative identification of hyperplastic parathyroid glands via gamma probe in secondary hyperparathyroidism. Material and Methods: This retrospective study was conducted using a prospective database of 59 patients who had undergone radioguided subtotal parathyroidectomy between 2004-2012. The patients were studied in 2 groups. Group 1 (n=31) received 37 MBq Tc-99m-MIBI intravenously in the surgical room approximately 10 mm before the beginning of the intervention and surgery was performed under gamma probe guidance. Group 2 (n = 28) received 555 MBq Tc-99m- MIBI intravenously 2 h before surgery, which was also performed under gamma probe guidance. Intraoperative gamma probe findings, laboratory findings, and histopathological findings were evaluated together. Results: Using acceptance of the histopathological findings as gold standard, sensitivity and specificity of intraoperative gamma probe for identifying hyperplastic parathyroid glands was 98% and 100%, respectively, in both groups. Conclusions: In the light of these findings, it is concluded that the low-dose Tc-99m-MIBI protocol might be preferable for intraoperative identification of hyperplastic parathyroid glands in secondary hyperparathyroidism patients because it was observed to be as effective as the high-dose Tc-99m-MIBI protocol. Furthermore, the low-dose protocol does not have the disadvantages that are associated with the high-dose protocol. (C) 2014 Elsevier Espana, S.L. and SEMNIM. All rights reserved.
Evaluation of the Effects of Recipient/Donor Gender on Early/Late Postoperative Renal Graft Functions by Renal Scintigraphy
(2014) Ayaz, Sevin; Gencoglu, Esra Arzu; Moray, Gokhan; Gozukara, Mehmet Yavuz; Haberal, Mehmet; https://orcid.org/0000-0003-4631-1683; https://orcid.org/0000-0003-2498-7287; https://orcid.org/0000-0002-3462-7632; 24918693; ABG-1864-2020; AAE-1041-2021; AAJ-8097-2021
Objectives: We discuss the effects of recipient/donor gender on renal allograft functions using scintigraphic parameters obtained 3 days after renal transplant and 1 year after transplant. Materials and Methods: This retrospective study included 76 renal allograft recipients (group one, 38 males; group two, 38 females). Patients underwent scintigraphic imaging with Tc- 99m DTPA on postoperative day 3 and 1 year after transplant. We used the Hilson perfusion index, maximum renal activity/background activity, ratio of renal activity at 20 minutes to renal activity at 3 minutes, time- to- peak activity, and glomerular filtration rate to measure quantitative parameters. Results: On postoperative day 3, the Hilson perfusion index, maximum renal activity/background activity, the ratio of renal activity at 20 minutes to renal activity at 3 minutes, time- to- peak activity, and glomerular filtration rate values for male/female recipients were similar (P = .65, P = .77, P = .38, P = .10, P = .99). The gender of donors was compared with the above- mentioned scintigraphic parameters of the recipients, and no statistically significant differences were found (P = .24, P = .25, P = .44, P = .29, P = .13). At 1- year follow- up, values obtained from group 1 and group 2 recipients were similar. After 1 year, chronic rejection developed in 15.7% of group 1 recipients and in 10.5% of group 2 recipients; acute rejection developed in 21% of group 1 recipients and in 23.6% of group 2 recipients. There were no statistically significant differences between the occurrence of acute rejection and the gender of recipients or donors (P = 1.00, P = .45). Conclusions: We observed no statistically significant differences between renal graft functions and gender of the recipients/donors during the early/late posttransplant period.
A Novel Cause of False-Positive Iodine-131 Whole Body Scintigraphy: Eczema
(2015) Gencoglu, Esra Arzu; Aktas, Ayse; Aras, Murat; 0000-0003-4631-1683; ABG-1864-2020