Browsing by Author "Gedizlioglu, Muhtesem"

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    Comparison of conventional and modern methods in determining ischemic stroke etiology by general and stroke neurologists
    (2019) Kunt, Refik; Kutluk, Mustafa Kursad; Tiftikcioglu, Bedile Irem; Afsar, Nazire; Erdemoglu, Ali Kemal; Gedizlioglu, Muhtesem; Ozturk, Vesile; 0000-0002-4573-3844; 30764594; I-7963-2019
    Background/aim: This study aimed to investigate the consistency between stroke and general neurologists in subtype assignment using the Trial of ORG-10172 in Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems. Materials and methods: Fifty consecutive acute ischemic stroke patients admitted to the stroke unit were recruited. Patients were classified by two stroke and two general neurologists, each from different medical centers, according to TOAST followed by the CCS. Each neurologist was assessed for consistency and compliance in pairs. Concordance among all four neurologists was investigated and evaluated using the kappa (kappa) value. Results: The kappa (kappa) value of diagnostic compliance between stroke neurologists was 0.61 (95% CI: 0.45-0.77) for TOAST and 0.78 (95% CI: 0.62-0.94) for CSS-5. The kappa (kappa) value was 0.64 (95% CI: 0.48-0.80) for TOAST and 0.75 (95% CI: 0.60-0.91) for CCS-5 for general neurologists. Compliance was moderate [kappa: 0.59 (95% CI: 0.52-0.65)] for TOAST and was strong [kappa: 0.75 (95% CI: 0.68-0.81)] for CCS-5 for all 4 neurologists. 'Cardioembolism' (91.04%) had the highest compliance in both systems. The frequency of the group with 'undetermined etiologies' was less in the CCS (26%) compared to TOAST. Conclusion: The CCS system improved compliance in both stroke and general neurologists compared with TOAST. This suggests that the automatic, evidence-based, easily reproducible CCS system was superior to the TOAST system.
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    Neurologic Complications of Renal Transplant
    (Başkent Üniversitesi, 2012-06) Ce, Pinar; Uslu, Adam; Nart, Ahmet; Gedizlioglu, Muhtesem; Coban, Gokmen; Koskderelioglu, Asli
    Objectives: Neurologic problems have a major effect on the survival and quality of life in renal transplant recipients. This study sought to review the incidence and character of neurologic complications after renal transplant. Materials and Methods: Medical records of 319 renal transplant recipients admitted to the Transplant Outpatient Clinic were reviewed retrospectively for neurologic complications. Results: Of the 319 transplant recipient patients reviewed, 124 patients (39%) were women and 193 patients (61%) were men. The mean patient age was 41 ± 11 years, and the transplanted kidney was received from deceased donors in 161 patients (51%) and living donors in 158 patients (49%). There were 50 patients (16%) who had neurologic complications, most commonly herpes zoster infection associated with immunosuppressive medication. Only 1 patient, who had glioblastoma multiforme, died. Treatment included corticosteroids in 296 patients (93%) and calcineurin inhibitors (including tacrolimus) in 111 patients (35%). Conclusions: Neurologic complications are common after renal transplant. Most complications are associated with immunosuppressive medications.