Browsing by Author "Eker, H. Evren"

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The Efficacy of Intra-Articular Lidocaine Administration in Chronic Knee Pain Due To Osteoarthritis: A Randomized, Double-Blind, Controlled Study
(2017) Eker, H. Evren; Cok, Oya Yalcin; Aribogan, Anis; Arslan, Gulnaz; https://orcid.org/0000-0002-7901-0185; https://orcid.org/0000-0003-3004-2626; https://orcid.org/0000-0002-4419-5693; 27485803; AAI-8769-2021; AAI-7998-2021; S-8336-2019
Background: Intra-articular injections for the treatment of knee pain due to osteoarthritis are performed when conservative therapies have failed. The intra-articular injection of lidocaine may be an effective treatment modality due to its neuronal membrane-stabilizing effect and long-lasting anti-inflammatory action. In this study, we compared the efficacy of intra-articular 0.5% lidocaine versus saline injection on pain, stiffness and physical function in patients with osteoarthritis. Methods: Patients with osteoarthritis were randomly allocated to two groups. Group I (n = 26) received 7 mL 0.5% lidocaine and group II (n = 26) received 7 mL saline into the painful knee for a series of three injections spaced by 1 week intervals under ultrasound guidance. Knee pain was measured with a numeric rating score (NRS) at baseline and 3 months after the 3rd injection. WOMAC scales, including pain (WOMAC-P), stiffness (WOMAC-S) and physical function (WOMAC-F), were assessed and recorded at baseline, 30 minutes after the 1st injection, immediately prior to the 2nd and 3rd injections and 3 months after the 3rd injection. Results: Demographic data were comparable between groups. The NRS after 3 months was significantly lower in group I (P = 0.001). The WOMAC-P, immediately prior to the 3rd injection and 3 months afterwards, was significantly lower in group I (P = 0.006, P = 0.001, respectively). The WOMAC-S was improved prior to the 3rd injection and sustained until 3 months in group I (P = 0.035, P = 0.004, respectively). The WOMAC-F was improved after the 1st injection and sustained until 3 months in group I (P = 0.002, P < 0.0001 and P < 0.0001, respectively). Conclusions: Intra-articular 0.5% lidocaine injection under ultrasound guidance has a potential role in the management of chronic knee pain due to osteoarthritis for a 3-month period. (C) 2016 Societe francaise d'anesthesie et de reanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.
Management of Isolated Infraorbital Neuralgia by Ultrasound-Guided Infraorbital Nerve Block with Combination of Steroid and Local Anesthetic
(2017) Cok, Oya Y.; Deniz, Sinan; Eker, H. Evren; Oguzkurt, Levent; Aribogan, Anis; https://orcid.org/0000-0003-3004-2626; https://orcid.org/0000-0002-9887-2864; https://orcid.org/0000-0002-7901-0185; https://orcid.org/0000-0002-4419-5693; 28235509; AAI-7998-2021; AAA-1269-2022; AAI-8769-2021
Patients with isolated peripheral branch neuralgia of trigeminal nerve usually receive traditional treatment such as medical therapy and interventional procedures targeting the entire trigeminal nerve or related ganglions. However, if the intractable pain is limited to a certain branch, the patient may also benefit from a peripheral and nerve-targeted interventional approach. Here, we report the management of a patient with isolated infraorbital neuralgia by ultrasound-guided infraorbital nerve block with steroid and local anesthetic combination. 48 years-old male patient diagnosed with trigeminal neuralgia was resistant to medical therapy for 3 years. The pain site was isolated to the area of the right nasal wing, right lateral incisor, the upper right canine and the first premolar teeth. His pain was an electric shock-like, throbbing and stabbing with a pain score of 8-9 according to numeric rating scale (NRS) and 18 according to the Leeds Assessment of Neuropathic Symptoms and Signs Pain Scale (LANSS). Following a diagnostic ultrasound-guided infraorbital nerve block with 1% lidocaine, the block was repeated twice with 15 mg lidocaine and 1.5 mg dexamethasone in a total volume of 1.5 mL in a month. The patient's NRS and LANSS scores decreased to 2 and 8, for approximately 21 months until this report was written. We suggest that ultrasound-guided infraorbital nerve block with dexamethasone and lidocaine combination may present as an initial interventional treatment option in patients with isolated infraorbital neuralgia. (C) 2016 Elsevier Inc. All rights reserved.
Oral 30% Glucose Provides Sufficient Sedation in Newborns During
(2017) Eker, H. Evren; Cok, Oya Yalcin; Cetinkaya, Bilin; Aribogan, Anis; 0000-0003-0866-7339; 0000-0003-3004-2626; 0000-0002-7901-0185; 0000-0002-4419-5693; 27999970; AAF-1346-2021; AAI-7998-2021; AAI-8769-2021; S-8336-2019
Newborns are often sedated during MRI but sedation itself creates adverse events and management is more challenging in this environment. Oral glucose/sucrose administration has been studied in newborns during painful procedures; however, its effectiveness in keeping newborns sleepy and motionlessness during painless procedures has not been demonstrated. The objective of this study was to describe effectiveness of oral 30% glucose administration by comparing with intravenous midazolam sedation for newborns during MRI. One hundred twelve ASA II-III newborns who required care in the ICU and were scheduled for MRI with sedation were included. Group I received 30% glucose solution orally with 0.5-1 ml increments up to 2 ml/3 kg doses and group II received intravenous 0.1 mg/kg midazolam with 0.05 mg/kg repetition. The procedure was considered satisfactory when MRI images were not disturbed by patient movement after oral glucose or intravenous midazolam administration. The efficiency of the techniques, additional dose and rescue sedation requirements, blood glucose levels following oral 30% glucose suckling and presence of adverse events were recorded. Demographic data was similar between groups. The efficiency of the procedures were similar between groups (78.9%, in group I and 66.1%, in group II). The blood glucose levels were within normal range in group I whereas transient desaturation and apnea occurred in 8 neonates in group II (p = 0.006). Oral 30% glucose administration for newborns during MRI is as effective as standard sedation protocol with midazolam. Thereby, we recommend and support the integration of this safe and reliable technique into routine practice for newborns during MRI.
Postoperative Analgesic Efficacy of Fascia Iliaca Block Versus Periarticular Injection for Total Knee Arthroplasty
(2016) Bali, Cagla; Ozmete, Ozlem; Eker, H. Evren; Hersekli, Murat A.; Aribogan, Anis; 0000-0002-7901-0185; 0000-0003-2615-1918; 0000-0001-5845-699X; 0000-0002-4419-5693; 27871565; AAW-9940-2021; AAI-8769-2021; AAI-8790-2021; AAI-7779-2021; S-8336-2019
Study objective: This study evaluated the postoperative analgesic efficacies of fascia iliaca block and periarticular drug injection techniques after TKA (total knee arthroplasty) surgeries. Design: Prospective, randomized clinical trial. Setting: University Teaching and Research Center. Patients: Seventy-one American Society of Anesthesiologists (ASA) I-III patients between 48 and 70 years of age who underwent total knee arthroplasty were randomized. Interventions: Tenoxicam (20 mg) was administered intramuscularly to both groups of patients 30 minutes before surgery. Patients were randomized into two groups to receive fascia iliaca block before the induction of anesthesia (Group FI) or periarticular drug injection during the surgery (Group PI). All surgeries were performed under general anesthesia using standard techniques. Postoperative analgesia was provided with patient-controlled intravenous morphine. Measurements: Total morphine consumption was the primary outcome measure and was recorded postoperatively at 1, 2, 6,12 and 24 hours. Pain levels at rest and on movement (knee flexion) were evaluated using the Visual Analogue Scale (VAS) and recorded at the same time points. Patients' demographics, rescue analgesic demands, side effects, hemodynamics, and satisfaction scores were also recorded. Main results: The groups had similar VAS scores both at rest and on movement (P > .05). However, the amount of cumulative morphine and use at each follow-up period was higher in Group PI (P < .0001). The groups did not differ significantly in rescue analgesic use or side effects, such as nausea/vomiting, hemodynamic variables, and patient satisfaction scores (P > .05). Conclusions: Fascia iliaca block may be used as an alternative method to periarticular injection, and it effectively reduces the amount of morphine used to relieve post-TKA pain. (C) 2016 Elsevier Inc. All rights reserved.