Browsing by Author "Deniz, Kagan"

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    Is The Incidence of Temporomandibular Disorder Increased in Polycystic Ovary Syndrome?
    (2014) Soydan, Sidika Sinem; Deniz, Kagan; Uckan, Sina; Unal, Asli Dogruk; Tutuncu, Neslihan Bascil; https://orcid.org/0000-0002-3798-7326; https://orcid.org/0000-0002-1816-3903; 25124832; ABG-5027-2020
    The prevalence of temporomandibular disorders is higher among women than men (ratio 3:1 -9:1). Polycystic ovary syndrome(PCOS) is the most common endocrine disorder in women, which is characterised by chronic low-grade inflammation and excess of androgenic hormones that lead to metabolic aberrations and ovarian dysfunction. Increased activities of various matrix metalloproteinases (particularly MMP-2 and 9) in the serum of these patients has been reported, and it has been hypothesised that high activities of MMP may contribute to loss of matrix and chronic inflammation of the fibrocartilage in temporomandibular disorders. Our aim was to evaluate the incidence of temopormandibular dysfunction in women with PCOS compared with an age-matched, disease-free, control group. We studied 50 patients with previously diagnosed PCOS and 50 volunteers who had normal menstrual cycles. We made a comprehensive clinical examination of the temporomandibular joint (TMJ) and muscles of mastication in both groups and recorded the Visual Analogue Scores (VAS) for pain. There were significant differences (p<0.001) in the incidence of temporomandibular disorders (n=43 (86%) in the PCOS group compared with n=12 24% in the control group), muscle tenderness(n=32 (64%) in the PCOS group compared with n=14 (28%) in the control group) and pain in the TMJ (mean (SD) VAS 2.9 (2.61) compared with 0.3 (1.56). We confirm the higher incidence and severity of disorders of the TMJ in patients with PCOS and suspect that chronic low-grade inflammation may play a part in the aetiology of the disease. Copyright (C) 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
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    Riga-Fede disease like ulcers in old age: A case report
    (2019) Mansur, Ayse Tulin; Deniz, Kagan; Ozdemir, Kerem
    Riga-Fede disease (RFD) is a traumatic, reactive benign disorder characterized by persistent ulceration on the tip or ventral surface of the tongue, seen mainly in infants and children. Lesions tend to develop after the eruption of natal or primary incisors, resulting from repetitive traumatic damage due to backward and forward movements of the tongue over the lower incisors. A literature survey has revealed a very limited number of reported cases of RFD in adults. Herein we reported a 70-year-old female patient who developed RFD-like ulcers on the tongue and buccal mucosa during the previous two months, while under treatment of dental implants. Histopathological examination and direct immunofluorescence of the ulcers and periulcer area did not yield a specific diagnosis. The lesions were resistant to systemic steroid treatment, however, after applying for a soft dental plate nightly for protection of the tongue and buccal mucosa, all ulcers completely healed in two months. With regard to the presented patient, we have reviewed the cases of RFD or RFD-like ulcers reported in adults and discussed the factors contributing to ulcer formation in our patient.