Browsing by Author "Demiroglu, Y. Z."

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A Case of Developing Rhino-Cerebral Mucormycosis After Liver Transplantation
(2017) Turunc, T.; Kursun, E.; Demiroglu, Y. Z.; Aras, F.; Arlier, I.; Haberal, M.; 0000-0002-9866-2197; 0000-0002-3462-7632; 0000-0001-7956-7306; AAZ-9711-2021; AAJ-8097-2021; AAG-5020-2020
How hematopoietic stem cell transplantation activity was affected during the pandemic? JACIE accredited center reflex
(2022) Kozanoglu, I.; Tepebasi, S.; Kursun, E.; Sen, N.; Unsal, Z. E.; Kis, C.; Boga, C.; Yesilagac, H.; Demiroglu, Y. Z.; Pocan, G.
Rapid Emergence of Colistin Resistance and Its Impact on Fatality Among Healthcare-Associated Infections
(2018) Aydin, M.; Ergonul, O.; Azap, A.; Bilgin, H.; Aydin, G.; Cavus, S. A.; Demiroglu, Y. Z.; Aliskan, H. E.; Memikoglu, O.; Menekse, S.; Kaya, S.; Demir, N. A.; Karaoglan, I.; Basaran, S.; Hatipoglu, C.; Erdinc, S.; Yilmaz, E.; Tumturk, A.; Tezer, Y.; Demirkaya, H.; Cakar, S. E.; Keske, S.; Tekin, S.; Yardimci, C.; Karakoc, C.; Ergen, P.; Azap, O.; Mulazimoglu, L.; Ural, O.; Can, F.; Akalin, H.; https://orcid.org/0000-0003-4044-9366; 29248504; HLX-0937-2023
This article describes the emergence of resistance and predictors of fatality for 1556 cases of healthcare-associated Gram-negative bloodstream infection in 2014 and 2015. The colistin resistance rate in Klebsiella pneumoniae was 16.1%, compared with 6% in 2013. In total, 660 (42.4%) cases were fatal. The highest fatality rate was among patients with Acinetobacter baumannii bacteraemia (58%), followed by Pseudomonas aeruginosa (45%), Klebsiella pneumoniae (41%), Enterobacter cloacae (32%) and Escherichia coli (28%). On multi-variate analysis, the minimum inhibitory concentrations for carbapenems [odds ratio (OR) 1.02, 95% confidence interval (CI) 1.01-1.04; P = 0.002] and colistin (OR 1.1, 95% CI 1.03-1.17; P = 0.001) were found to be significantly associated with fatality. (C) 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
Scoring System Evaluation For Orbital Exenteration In Patients With Rhino-Orbito-Cerebral Mucormycosis
(2022) Ulas, B.; Kursun, E.; Turunc, T.; Demiroglu, Y. Z.; Pelit, A.; https://orcid.org/0000-0002-0722-6964; https://orcid.org/0000-0002-0662-2033; 34823889; F-2809-2015
Purpose. - To evaluate our patients with rhino-orbito-cerebral mucormycosis according to a new scoring system and to compare those who underwent orbital exenteration persuant to a new threshhold. Methods. - Mucormycosis is a fungal disease that can be of acute onset, aggressive, and angioinvasive. Aggressive surgical debridement, long-term systemic antifungal therapy, and treatment of underlying predisposing factors are essential to the treatment. However, orbital exenteration is a very difficult decision to make, particularly in patients with orbital involvement, because there is little information in the literature, resulting in limited support for making this aggressive surgical decision. In this study, our 43 cases of mucormycosis were evaluated in terms of orbital exenteration using a scoring system (including clinical signs and symptoms, ophthalmoscopic findings, and radiologic results) developed by Shah et al., which establishes indications for orbital exenteration in mucormycosis. Results. - According to our study, if the threshold score for exenteration is 19.0, the sensitivity was 100% and specificity was 97%, providing better results than the 23.0 threshold score determined by the reference study for exenteration. When these two score thresholds were compared, there was a statistically significant difference. Conclusion. - We believe that this scoring system may be beneficial to use for orbital exenteration in patients with mucormycosis. Prospective studies in large case series are required to determine the most appropriate threshold score. (C) 2021 Elsevier Masson SAS. All rights reserved.