Browsing by Author "Dellen, David van"

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Hand-Assisted Laparoscopic Donor Nephrectomy in Patients With Aberrant Inferior Vena Caval Anatomy
(Başkent Üniversitesi, 2010-09) Dellen, David van; Inston, Nicholas G.; Ready, Andrew R.
Objectives: Hand-assisted laparoscopic donor nephrectomy has become an established technique for live-donor organ retrieval. In most cases, the left kidney is removed because of its more favorable anatomic relations, particularly with the major abdominal vessels. Materials and Methods: We present 2 cases of live donation in which a hand-assisted laparoscopic approach was used to remove the right kidney as indicated by the presence of aberrant vascular anatomy, 1 being situs inversus totalis, the other a left-sided inferior vena cava. Results: A 41-year-old woman and a 51-year-old man underwent assessment for live-kidney donation. During preoperative investigation, they underwent magnetic resonance imaging that demonstrated situs inversus totalis and a left-sided inferior vena cava. No contraindications to live donation were found during the investigation. In both cases, a right donor nephrectomy was performed owing to an anatomically longer right renal vein. Living donation proceeded without complication in both cases, and both patients had uneventful recoveries. Conclusions: Abnormalities in vascular anatomy should not be considered an absolute contraindication to donation, even by the hand-assisted laparoscopic donor approach. The use of magnetic resonance scanning preoperatively allows detailed planning of the approach required.
Intraoperative Hyperkaliemia Complicating Hand-assisted Live-donor Nephrectomy
(Başkent Üniversitesi, 2011-12) Dellen, David van; Augustine, Titus; Wadsworth, Richard; Tavakoli, Afshin
Objectives: Live donation has become increasingly valuable as a potential source of kidneys for transplant with hand-assisted laparoscopic donation is an important method of organ procurement. An important consideration is adequate preoperative and intraoperative planning, and precautions to minimize potential risks in the donor while providing a graft with good primary function. Materials and Methods: We present a case of live donation in which a hand-assisted laparoscopic approach was used to facilitate kidney donation. The process was complicated by a period of profound intraoperative hyperkalaemia, subsequently ascribed to rhabdomyolysis owing to muscle necrosis. Results: A 46-year-old man underwent assessment for live kidney donation for his brother. Preoperative investigations revealed normal renal function with no contraindications to donation. However, at the time of donation, a period of unexplained hyperkalaemia occurred that resolved spontaneously with fluid resuscitation and aggressive diuresis. After surgery, he was demonstrated to have an elevated creatine kinase level associated with unilateral gluteal pain and bruising. There were no long-term complications, and the donor made a full recovery with normal renal function. Hyperkalaemia was ascribed to extensive rhabdomyolysis owing to positioning on the operating table at the time of surgery. Conclusions: Rhabdomyolysis associated with laparoscopic renal surgery requires prompt recognition and treatment while unexplained hyperkalaemia may herald its onset. It is important that an increased sense of vigilance is given to patients with increased muscularity or body mass, especially in donor nephrectomy patients, because of its effect on the remaining solitary kidney.